Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0344307 (analgesia)
 28,200 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

The Wolff-Parkinson-White syndrome can complicate the anesthetic management of the pregnant patient. These patients are prone to arrhythmia that can be accompanied by hypotension. Maintenance of a stable heart rhythm is necessary for both maternal and fetal well-being. An optimal anesthetic regimen that provides minimal cardiac and hemodynamic changes has not been determined. Intrathecal administration of opiates for obstetric analgesia has been found to provide hemodynamic stability because no motor or sympathetic blockade occurs. The authors report the successful use of intrathecal injection of morphine for labor analgesia in a patient with Wolff-Parkinson-White syndrome.
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PMID:Hyperbaric intrathecal morphine analgesia during labor in a patient with Wolff-Parkinson-White syndrome. 654 3

The rare congenital heart defect of Ebstein's anomaly is characterized by downward displacement and elongation of the septal cusp of tricuspid valve. As a result, it is often associated with a thin-walled and poorly contractile right ventricle, an enlarged atrium, tricuspid regurgitation, atrial septal defect with intracardiac shunt, pulmonary hypertension and tachyarrhythmia. Published reports or studies on analgesic and/or anesthetic management of laboring parturients with Ebstein's anomaly are limited. We present an evidence-based case report of the successful management of an obese laboring parturient with Ebstein's anomaly and Wolff-Parkinson-White syndrome under epidural analgesia. We reviewed the literature and present the best evidence available or its lack of, and the reasoning in supporting the choice of the analgesic and anesthetic management.
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PMID:Evidence-based case report for analgesic and anesthetic management of a parturient with Ebstein's Anomaly and Wolff-Parkinson-White syndrome. 1712 99

The most common arrhythmia seen during pregnancy is paroxysmal supraventricular tachycardia and Wolff-Parkinson-White syndrome accounts for majority of this in such population. The presence of pre-disposing factors may facilitate the onset of tachyarrhythmias in previously asymptomatic parturients with the WPW syndrome such as increased hemodynamic, hormonal, autonomic, and emotional changes. Therefore, meticulous monitoring is essential perioperatively. Epidural anesthesia providing added advantage of hemodynamic stability and post-operative analgesia is preferred in such pregnant patients undergoing emergency cesarean section.
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PMID:Anesthetic management of Wolff-Parkinson-White syndrome in a pregnant patient posted for emergency caesarean section. 2588 95