Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0344232 (blurred vision)
 2,072 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

The Creutzfeldt-Jakob disease (CJD) is rare spongiform encephalopathy. Its main symptoms are rapidly progressing dementia, myoclonic jerks, visual disturbances, ataxia, and pyramidal and extrapyramidal signs. A case of sporadic form of the CJD is reported, with blurred vision as one of the first symptoms. This symptom occurred shortly after vaccination against influenza, and was accompanied by other signs suggesting postvaccinal encephalitis. However, at a later stage of the disease typical changes were found in EEG recording and in magnetic resonance imaging (MRI). The presence of the 14-3-3 protein was detected in the patient's cerebrospinal fluid. The diagnosis of sporadic Creutzfeldt-Jakob disease was verified neuropathologically.
Neurol Neurochir Pol
PMID:[Diagnostic difficulties in Creutzfeldt-Jakob disease--case report]. 1517 42

Nasolacrimal duct obstruction is a common condition in patients who visit otolaryngologists and ophtalmologists. The patients complain of epiphora and blurred vision. Reconstruction of lacrimal drainage provides great improvement in a patient's quality of life. On the base of the world literature and the own experience, several surgical techniques of the lacrimal system are presented and analyzed regarding indications and results: dacryocystorhinostomy (DCR), canaliculodacryocystorhinostomy (CanDCR), con-junctivodacryocystorhinostomy (ConDCR) and intubation. External DCR usually involves extensive removal of bone at the lacrimal fossa and hence risks disruption of the lacrimal pump mechanism. The development of endonasal microsurgery (endoscope, microscope) have awakened interest in an internal DCR in treatment nasolacrimal obstruction. Endonasal microscopic dacryocystorhinostomy become an important alternative to the classical external DCR. This method preserves intact the normal function of the lacrimal pump, yields cosmetic excellent results and allows at the same time management of the concomitant sino-nasal pathology.
Otolaryngol Pol 2006
PMID:[Review of the basic methods of surgical treatment of lacrimal duct stenosis]. 1690 44

Posterior reversible encephalopathy syndrome (PRES) is a set of neurological symptoms including impaired consciousness, cognitive disorders, seizures, blurred vision, dizziness and headache. The symptoms are closely related to the location of pathological changes in the brain; bilateral occipitto-parietal region is most often affected. Both focal neurological symptoms and encephalopathy are usually transient. We present the case of 64-year-old woman with PRES. She suffered from many internal diseases and was admitted to the hospital due to impaired consciousness, speech disorders, balance disorders. Significant neurological deterioration was observed within several days from the onset. Differential diagnosis included stroke and viral neuroinfection (cytosis 23 cells /ul, protein level of 93 mg/dl); magnetic resonance examination revealed lesions typical for posterior reversible encephalopathy.After 6 weeks of hospitalization patient condition improved, but did not restore to the premorbid state. The patient was discharged with generalized cognitive impairment.
Pol Merkur Lekarski 2016 Apr
PMID:Posterior reversible encephalopathy syndrome with neurological sequelae - a case report. 2713 27