Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0344232 (blurred vision)
 2,072 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Twenty persons with chronic low back pain participated in a clinical study to evaluate the effects of gravity traction. Each subject was instructed in the use of three devices, two for inversion and one for upright suspension traction. Baseline pulse and rate blood pressure were recorded before and after traction. Periods of traction did not exceed 20 minutes. The order of use of the devices was randomized. Each participant was monitored for significant side effects and was questioned to determine which device was best tolerated, easiest to use, or caused changes in back symptoms. Lateral lumbar spine radiographs were taken with the subject in the standing position and after varying periods of inversion. Observations included the following: An average increase in blood pressure of 17.2 systolic (range 4-34) and 16.4 diastolic (range 2-50) while in the inverted position. An average decrease in heart rate of 16.4 beats per minute (range, 4-32). No significant physiologic changes of blood pressure or pulse were observed in patients using GLR suspension traction; distraction of the lower lumbar intervertebral spaces (range, 0.3 to 4.0 mm) with inverted traction in all cases; side effects including periorbital and pharyngeal petechiae (one patient), persistent headaches (three patients), persistent blurred vision (three patients), and contact lense discomfort (one patient); and improvement of low back symptoms in 13 of the 16 symptomatic patients. Although these devices make lumbar traction practical in a home setting, their use should be under medical supervision because of possible side effects.
 ...
PMID:Inversion devices: their role in producing lumbar distraction. 315 39

Fluoroquinolone medications have been shown to contribute to tendinopathies, cardiotoxicity, and neurotoxicity. Low back pain is a common musculoskeletal condition for which chiropractic treatment is most often sought. This case report details a patient presenting with low back pain and a history of fluoroquinolone toxicity. The patient was initially treated with chiropractic manipulation, which increased her symptoms. She was then referred to an osteopathic physician who treated the patient with intravenous antioxidants and amino acids, an elimination diet, and probiotic supplementation. Within 4 months of therapy, the patient reported a decrease in pain, a resolution of her dizziness, shortness of breath, panic attacks, tachycardia, and blurred vision. After an additional 8 weeks of antioxidant therapy, she reported further reductions in pain and improved disability. People susceptible to fluoroquinolone toxicity may present with common musculoskeletal symptoms. A past medical history and medication history may help to identify this population of patients. People presenting with fluoroquinolone toxicity may have unidentified contributing factors that predispose them to this anomaly. This patient reported improvements in pain and disability following antioxidant amino acid therapy for a total of 6 months. The natural history of fluoroquinolone toxicity is unknown and may account for the observed improvements.
...
PMID:Fluoroquinolone toxicity symptoms in a patient presenting with low back pain. 2476 86

The case reported is of a 47-year-old man with an undetected ferromagnetic metallic intraocular foreign body in the right eye who underwent elective MR examinations for chronic neck and low back pain. The patient underwent the MR scans and subsequently developed blurred vision in his right eye caused by a hyphema associated with an anterior chamber metallic foreign body. Case reports of orbital injuries in patients with intraocular metallic foreign bodies undergoing MRI are rare, with only one prior report in the radiology literature. While the incidence of intraocular foreign bodies causing injury in patients undergoing MRI is likely rare even among patients with foreign bodies, this case demonstrates that complications from an IMFB can potentially have a subtle presentation. Our case also illustrates potential limitations of pre-MRI safety questionnaires, particularly pertaining to a patient's understanding of the thoroughness of foreign body removal.
...
PMID:Undetected intraocular metallic foreign body causing hyphema in a patient undergoing MRI: a rare occurrence demonstrating the limitations of pre-MRI safety screening. 2552 8