Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0344232 (blurred vision)
 2,072 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

A 38-year-old man acquired a Pseudomonas aeruginosa wound infection after transplant nephrectomy. After an initial response to therapy, Pseudomonas sepsis developed, and he was readmitted to the hospital. Two days after admission, blurred vision developed. Ocular examination revealed a severe vitritis and exudate in the pupillary space on the right side. Endogenous endophthalmitis was suspected, and a diagnostic vitreous aspiration yielded P aeruginosa on culture. The patient was treated with intravitreal, subconjunctival, and topical antibiotics as well as periocular steroids, and was able to achieve useful vision before his death from his systemic illness.
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PMID:Successful management of Pseudomonas endogenous endophthalmitis. 640 May 66

Endogenous endophthalmitis is a rare but devastating complication of bacteremia. Klebsiella pneumoniae is reported to be the leading organism of endogenous endophthalmitis in Taiwan, and the prognosis of endogenous Klebsiella pneumoniae endophthalmitis is extremely poor. A 46-year-old male patient was hospitalized because of fever, chills, and consciousness disturbance for 1 day. Meningitis was the impression by clinical presentation and findings of cerebrospinal fluid analysis. Parenteral ceftriaxone (4 g/day) and gentamicin (180 mg/day) were given, and his consciousness gradually cleared. On hospital day 6, he complained of blurred vision in both eyes and floaters in the left eye for 1 day. After ophthalmic examination, bilateral endogenous endophthalmitis was diagnosed. After aggressive treatment with intravitreal antibiotics and trans pars plana vitrectomy, the visual outcome of both eyes was better than those of other reported cases.
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PMID:Bilateral endogenous Klebsiella pneumoniae endophthalmitis associated with meningitis-useful vision regained after treatment: case report. 1109 47