Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0344232 (blurred vision)
 2,072 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

A 46-year-old extremely obese black woman presented with headaches, blurred vision, and visual obscurations. Her exam was notable for bilateral severe papilledema, retinal hemorrhages, and lethargy. Her CAT scan was normal, and a spinal tap revealed a very high opening pressure. Although this patient's presentation mimicked pseudotumor cerebri, the lethargy and retinal hemorrhages were atypical. Her hospital evaluation was notable for elevation of the serum bicarbonate level, and she was subsequently found to have hypoxia and hypercapnia on a blood gas. The patient was diagnosed as Pickwickian syndrome, with obstructive sleep apnea. Treatment of the pulmonary problem resulted in dramatic improvement in her eye findings and her lethargy, and optic nerve sheath fenestration was not necessary.
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PMID:Disk edema in an overweight woman. 854 13

A 46-year-old man was diagnosed with obstructive sleep apnea and began using a nasal continuous positive airway pressure (CPAP) during sleep for a month. He presented with the complaint of a painful blurred vision in his left eye upon awakening two days earlier. His visual acuity was 20/25 both eyes. There was a mild anterior chamber reaction in the left eye. Fundus examination showed a localized choroidal effusion at the inferotemporal part of the left retina. The patient received topical 0.1% dexamethasone four times daily and temporarily discontinued the CPAP. By one week after treatment, the choroidal effusion was completely resolved
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PMID:Choroidal effusion following continuous positive airway pressure treatment. 1962 21