Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0344232 (blurred vision)
 2,072 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

215 preschool siblings of children presenting with squint/amblyopia were screened by refraction after cycloplegia. The presence of +2.00 or more D of spherical hypermetropia in both eyes, or +1.00 or more D sphere or cylinder of anisometropia was significantly associated (P=0.0779%) with that child being identified 2+ years later as having either squint or amblyopia or both. Astigmatism of +1.50 or more D in either eye was significantly associated with anisometropia (P=0.000 0013%). If bilateral hypermetropia of +2.00 or more DS and/or +1.50 or more D of astigmatism in either eye had been taken as criteria for abnormality (ignoring anisometropia), there was a more significant association (P=0.0025%) between refraction and squint/amblyopia in these siblings. Such a child had 4 times more chance of having a visual defect than one who had no error of refraction when screened. These findings suggest that an environmental factor such as blurred vision may be relatively more important as a cause of squint/amblyopia than a genetically determined neurological abnormality.
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PMID:Refraction as a means of predicting squint or amblyopia in preschool siblings of children known to have these defects. 43 40

We treated four patients with corneal burns resulting from mishaps while using electric curling irons. In all cases, the burns were symptomatic with blurred vision, tearing, pain, and photophobia. Injury was limited to the corneal epithelium, and management included debridement, topical antibiotics, cycloplegia, and pressure patching. Burns resolved completely within 48 hours after debridement and patching.
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PMID:Contact thermal burns of the cornea from electric curling irons. 647 57

Synkinetic lid and ocular movements after traumatic or non-traumatic, acquired oculomotor palsy are well known. Less often misdirection in the intraocular muscles is observed. A 20-year-old female patient suffered from congenital palsy of the third nerve of the left dominant eye. She had residual small-angle exotropia after having extraocular muscle surgery four times during childhood, e.g., after high-dosage recess-resect procedures on the horizontal recti of her left eye. There was an anisocoria with a miotic pupil in the left eye when fixating in the primary position and when attempting right gaze. The patient complained of blurred vision at far fixation in the primary position. Her visual acuity was 0.8 in the primary position and 1.25 in 7 degrees left gaze. Retinoscopy of the left eye revealed a 1-1.25 myopic increase for the primary position. Surgical and non-surgical treatment (e.g., cycloplegia plus bifocal glasses, induced change of the leading eye) is discussed.
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PMID:[Synkinesia of the internal eye muscles in congenital third nerve paralysis]. 817 59

A 33-year-old woman with a history of relapsing-remitting multiple sclerosis presented with complaints of episodic horizontal diplopia and blurred vision over the past two months. The patient gave a past history of similar episodes of diplopia that had occurred with previous clinical relapses of her multiple sclerosis. On eye movement examination, the patient exhibited intermittent spasms of convergence coupled with miosis. On upward gaze, the convergence and miosis became more marked. An auto-refraction revealed variable measurements in both eyes, consistent with accommodative spasms. A cycloplegic auto-refraction revealed significantly lower myopia present in both eyes than the initial pre-cycloplegic auto-refraction with minimal variability in readings. Symptomatic relief was achieved by cycloplegia and spectacle correction.
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PMID:Spasm of the near reflex in a patient with multiple sclerosis. 1736 15

Accommodative spasm is a rare condition occurring in children, adolescents, and young adults. A familial tendency for this binocular vision disorder has not been reported. I describe accommodative spasm occurring in a brother and sister. Both children presented on the same day with complaints of headaches and blurred vision. Treatment included cycloplegia drops and bifocals. Siblings of patients having accommodative spasm should receive a detailed eye exam with emphasis on recognition of accommodative spasm.
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PMID:Accommodative spasm in siblings: a unique finding. 2053 25