Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0344232 (blurred vision)
2,072 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

The analysis of three controlled studies comparing mianserin and clomipramine shows that none of them has elicited statistically significant differences between drugs, although populations were different: primary depression almost equally divided in endogenous and exogenous cases (de Buck), primary depression mostly neurotic (Pinder), involutional melancholia (Blaha). The only difference found as to efficacy was a more precocious onset of action for mianserin in the group of the endogenous depressions (de Buck). Mianserin causes significantly less side effects, above all as to hypotension, dry mouth, tremor and blurred vision.
...
PMID:[Analysis of controlled studies comparing mianserin and clomipramine (author's transl)]. 703 87