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Target Concepts:
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Query: UMLS:C0344232 (
blurred vision
)
2,072
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
A 27-year-old women with
chondrosarcoma
of the ethmoid sinus extending to the anterior fossa had initial symptoms of
blurred vision
on the left and slight proptosis. Neuroradiological examination, however, disclosed that the tumor extended not only to the anterior cranial fossa, but also to the orbit, nasal cavity, and maxillary sinus. It is difficult to predict the biological behavior of
chondrosarcoma
by means of histological examination. The effectiveness of radiotherapy, chemotherapy, or both is also a matter of controversy. Clinical aspects of
chondrosarcoma
are briefly discussed.
...
PMID:Chondrosarcoma of the ethmoid sinus extending to the anterior fossa. 733 13
Ectopic pituitary adenomas usually occur within sphenoid sinus or nasopharynx, and seldom within the clivus. There is only a single reported example of ectopic adenoma with clinical apoplexy, albeit not from clivus. We report a 78-year-old male with known prostate carcinoma admitted with acute onset of
blurred vision
, suggestive of apoplexy. Work-up revealed unilateral cranial nerve VI palsy and neuroimaging showed a mass confined to the clivus; sellar region was normal. Preoperative considerations included chordoma,
chondrosarcoma
, or metastatic prostate carcinoma to bone. Resection was via endoscopic transsphenoidal approach to the clivus. An ectopic null cell pituitary adenoma with bland infarction was identified as the cause of the patient's clinical apoplexy. No antecedent precipitating factors for apoplexy were present; specifically the patient had not received leuprolide preoperatively, a known precipitant of pituitary apoplexy in prostate cancer patients who receive drug. We review the literature on ectopic clival pituitary adenomas, apoplexy in ectopic adenomas, and the link between apoplexy and leuprolide usage.
...
PMID:Ectopic pituitary adenoma of the clivus presenting with apoplexy: case report and review of the literature. 2219 1
We report a rare case of
chondrosarcoma
metastatic to the choroid. A 64-year-old male with a history of
chondrosarcoma
metastatic to the lungs and to the spine presented with
blurred vision
. A choroidal tumor was found. Fine-needle biopsy confirmed the histologic identity of the tumor as
chondrosarcoma
. Metastatic spread of
chondrosarcoma
to the eye is extremely rare. When present, lesions may grow rapidly, and systemic prognosis is poor. Co-management with medical oncology is of utmost importance. This is the third case of
chondrosarcoma
metastatic to the choroid in the literature and the first with bilateral involvement.
...
PMID:Chondrosarcoma Metastasis to the Choroid. 3136 83
