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Query: UMLS:C0344232 (blurred vision)
 2,072 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

The effect of hydroxyurea on blood viscosity was studied in 10 patients with Philadelphia chromosome positive chronic myelogenous leukemia (CML) and hyperleukocytosis (white blood cell counts over 200 x 10(9)/l). All the patients had visible manifestations of leukostasis such as headache, blurred vision, retinal hemorrhage, pulmonary infiltrates, etc. Contraves LS 30 viscometer was used to measure the blood viscosity at 37 degrees C and at different shear rates on paired leukemic blood samples obtained before and after the hydroxyurea treatment. The blood viscosity was significantly higher in CML patients then normal subjects and decreased after treatment with hydroxyurea. In all the cases plasma viscosity was unaffected by the treatment.
Physiol Chem Phys Med NMR 1991
PMID:Effect of hydroxyurea on blood viscosity in chronic myelogenous leukemia with hyperleukocytosis. 181 5

Immediately after a flight from Europe to the USA a 45-year old German woman noticed an unilateral protrusion of the eye with retrobulbar pressure, diplopia and blurred vision. Except for a nasal polypectomy 23 years ago the past medical history was unremarkable. The above mentioned symptoms disappeared spontaneously but reoccurred after a second flight to Turkey six months later. The ultrasound examination of the orbital cavity showed a large suprabulbar mucocele which displaced the eyeball downwards. An intracerebral expansion was excluded by NMR-tomography. The mucocele was removed surgically but reappeared when the patient had a cold. All symptoms disappeared within 2 weeks of taking antibiotics. Fluctuation of the air pressure in the aeroplane and below atmosphere pressure let the air in the sinuses expand. Via a connection between the nasal sinuses and the mucocele, the mucus is forcibly pressed into the mucocele, and the internal pressure rises. The clinical symptoms will therefore increase suddenly during a flight. The ultrasound examination is a reliable method for the differential diagnosis of retrobulbar tumor and should be used for follow-up examinations because of the simplicity and safety of the method.
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PMID:[Value of 10 MHz ultrasound in diagnosis and follow-up of retrobulbar mucocele]. 1139