Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0343525 (Lemierre's syndrome)
 443 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Lemierre syndrome is a rare complication of acute tonsillitis. It is caused by the anaerobic bacterium Fusobacterium necrophorum and is characterized by bacteremia and septic thrombosis of the internal jugular vein. Dissemination of septic emboli may occur. The diagnosis can be difficult since different organs can be involved. We discuss a case of Lemierre syndrome in a 35-year-old woman with isolated thrombophlebitis of the facial vein and fusobacteria growth in blood culture. This case emphasizes the need for awareness of the condition.
Open Forum Infect Dis 2014 Sep
PMID:Isolated facial vein thrombophlebitis: a variant of lemierre syndrome. 2573 23

Complications of acute mastoiditis can occur in about 10-20% of cases. Clival syndrome is a rare complication of mastoiditis, involving the 6th and 12th cranial nerves. We describe a case of a child with mastoiditis and presumed Lemierre syndrome complicated by clival syndrome.
Pediatr Infect Dis J 2015 Sep
PMID:Clival Syndrome Secondary to Anaerobic Mastoiditis in A 2-Year-Old Child. 2616 49

Lemierre's syndrome is a dangerous potential sequela of pharyngitis that results in septic thrombophlebitis of the internal jugular vein. A high index of suspicion is needed to consider this diagnosis in the workup of pharyngitis and should be aggressively treated once. Gram-negative anaerobic bacteria, mainly Fusobacterium necrophorum are implicated. Before the antibiotic era, Lemierre's syndrome was common and often fatal. But with the introduction of penicillin in the 1940s, the incidence of the syndrome dropped, and it eventually became known as the "forgotten disease". Since the 1990s, however, there has been a marked resurgence of Lemierre's syndrome. Although uncommon, clinicians need to be aware of this condition because patients with Lemierre's syndrome require prompt and appropriate antimicrobial therapy.
Recenti Prog Med 2016 Sep
PMID:[Let us not forget the Lemierre's Syndrome.] 2772 58

Cavernous sinus thrombosis (CST) is a severe disease which can result from infection of any of the tissues drained by the cavernous sinus. We here review eight cases, including a 12-year-old girl, all secondary to sphenoid sinusitis. The clinical manifestations, laboratory data, imaging findings, pathogens, medications, surgical treatment and clinical outcomes were analyzed. All eight patients had headache and five of them fever. All cases were associated with one or more ophthalmic symptoms. In four cases, computed tomography/magnetic resonance imaging showed isolated sphenoid sinusitis. In three cases, streptococci were isolated from blood culture and two cases showed Staphylococcus aureus in blood and sinus cultures. In seven cases, surgery was undertaken. All eight subjects received antibiotics, and 5 were administered intravenous ceftriaxone and metronidazole. Six subjects received anticoagulation therapy and one received corticosteroids. No mortality was recorded. Three cases showed sequelae, including Lemierre syndrome, ophthalmic complaints, and cranial nerve paralysis. In conclusion, the management of CST should include intravenous antibiotic therapy, combined with endonasal sinus surgery.
Infect Dis (Lond) 2017 Sep
PMID:A review of eight cases of cavernous sinus thrombosis secondary to sphenoid sinusitis, including a12-year-old girl at the present department. 2853 28

Lemierre syndrome is a rare, grave and life-threatening disease characterized by a septic thrombophlebitis of the internal jugular vein. Fusobacterium necrophorum is the most causative germ but sometimes others germs can be responsible. The authors report the first published case of Lemierre syndrome caused by a coinfection Levinea sp - Mycobacterium tuberculosis.
J Stomatol Oral Maxillofac Surg 2019 Sep
PMID:An unusual cause of Lemierre Syndrome. 3077 50

A pre-school aged boy presented to the Pediatric Emergency Department with a high grade fever and neck pain and stiffness. Blood culture was positive for methicillin-sensitive Staphylococcus aureus (MSSA) and Doppler ultrasound of the neck revealed partial thrombosis of the left internal jugular vein. He was diagnosed with Lemierre's syndrome (LS) and treated with a prolonged course of antibiotics and anticoagulation. After discharge home, he was followed in the outpatient clinics and had a full recovery. This case report will highlight the presentation of LS and will briefly review the microbiology of this condition.
J Infect Public Health 2020 Sep
PMID:A 4-year-old boy with Lemierre's syndrome caused by methicillin-sensitive Staphylococcus aureus. 3250 2

Symptoms of coronavirus disease 2019 overlap with other important illnesses affecting young adults. We report a case of a 17-year old male presenting to the emergency department in the midst of a pandemic with symptoms of coronavirus disease 2019. He had fever, dyspnea, chest pain, and myalgias, with bilateral infiltrates on chest radiograph, and developed septic shock secondary to infectious thromboembolic events. However, his blood cultures grew group G streptococcus secondary to his oropharyngeal infection, and he experienced an infectious thrombus in the internal jugular vein, consistent with the rare but well-described Lemierre's syndrome. This case report calls attention to the importance of maintaining differential diagnoses and thereby minimizing the biases and assumptions that come with clinical care during a pandemic.
J Am Coll Emerg Physicians Open 2020 Sep 26
PMID:A teenager with fever, chest pain, and respiratory distress during the coronavirus disease 2019 pandemic: a lesson on anchoring bias. 3304 18


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