Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C0343525 (
Lemierre's syndrome
)
443
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
Introduction.
Chromobacterium violaceum
is an opportunistic human pathogen, associated with significant mortality, and has been reported in patients with chronic granulomatous disease (CGD), a
genetic condition
causing impaired phagocytosis.
Case presentation.
A 28-year-old man with a history of CGD presented with fever, pharyngitis, cervical lymphadenopathy and internal jugular vein thrombosis, following travel to the rural Solomon Islands.
C. violaceum
was recovered from his blood. The patient recovered after treatment with meropenem and trimethoprim/sulfamethoxazole.
Conclusion.
To the best of our knowledge, this is the first case report of internal jugular vein thrombophlebitis (
Lemierre's syndrome
) caused by
C. violaceum
in a patient with CGD. A review of the literature demonstrated that the diagnosis of
C. violaceum
preceded the diagnosis of CGD in the majority of cases. This case emphasizes the importance of this organism in patients with CGD who live in or visit tropical areas.
...
PMID:
Chromobacterium violaceum
infection in chronic granulomatous disease: a case report and review of the literature. 2834 1
