Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0338671 (Steroids)
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Human Gene/Protein
protein tyrosine phosphatase type IVA, member 1 11.7
WNT1-inducible-signaling pathway protein 2 10.1
zinc finger protein 36, C3H type-like 1 10.1
PAQR6 9.7
interleukin-22 binding protein 9.4
17beta-estradiol dehydrogenase 9.4
LY6/PLAUR domain containing 4 9.4
BAK1 protein 9.4
PAQR10 9.1
GABA transport protein 9.1
UDP-glucuronosyltransferase 1A10 8.9
PAQR9 8.9
cytochrome P450 7B1 8.7
Helicase-like transcription factor 8.7
truncated progesterone receptor 8.7
band 7 integral membrane protein 8.7
mPR 8.7
steroid 18-hydroxylase 8.5
HSD11 8.5
MNAR 8.5
claudin 8 8.5
GPER protein 8.3
DHHC-7 8.3
tyrosinase-like 8.2
20 alpha-hydroxysteroid dehydrogenase 8.2
17-ketoreductase 8.1
AKR1D1 8.0
Delta(5)-3-ketosteroid isomerase 8.0
estrone sulfatase 7.9
P450aldo 7.9
PAQR7 7.9
hyodeoxycholic acid 7.7
CYP39A1 7.7
PAQR5 7.6
PSN1 7.6
ABHD2 7.5
taxilin 7.5
serum and glucocorticoid regulated kinase 7.5
OATP3A1 7.4
PAIRBP1 7.4
more...
Disease
Iatrogenic glaucoma 11.7
Total fluid volume increased 11.7
Pulmonary Lymphomatoid Granulomatosis 11.7
Steroids 11.7
Anabolic Steroids 10.4
Leptospiral uveitis 10.1
Sex cord-stromal tumor 10.1
Nasal sarcoidosis 10.1
Diffuse Infiltrative Lymphocytosis Syndrome 10.1
Livedo vasculitis 9.7
Chronic thrombocytopenia 9.1
Acquired factor VIII deficiency 8.7
Sclerema 8.5
Chronic inflammatory disease 8.4
CMO II deficiency 8.3
Erosive adenomatosis of the nipple 8.1
Irreversible shock 8.1
Steroid myopathy 7.9
Pleural adhesions 7.9
Febrile ulceronecrotic Mucha-Habermann disease 7.8
pituitary cancer 7.8
Acute viral bronchiolitis 7.7
Subretinal hemorrhage 7.7
renal rickets 7.6
Bacterial keratitis 7.6
DEND 7.5
Chronic periaortitis 7.5
Autoimmune inner ear disease 7.3
Ophthalmoplegic migraine 7.3
Drug-induced immune hemolytic anemia 7.3
Diabetic maculopathy 7.2
IgG gammopathy 7.1
Pseudohypoaldosteronism 7.0
pigeon breeder's lung 6.9
unable to remember 6.9
Pretibial myxedema 6.9
11 beta-hydroxylase deficiency 6.7
Eosinophilic colitis 6.7
Autoimmune enteropathy 6.7
adrenal disorder 6.7
more...
Symptom
Osteoarticular pain 10.1
Popeye sign 9.1
Sympathetically maintained pain 8.4
pain in the buttock 7.0
thoracic back pain 6.0
Cushingoid 5.0
elevated mood 5.0
Visual symptoms 4.9
Cushingoid 4.9
Visual disturbances 4.9
generalized erythema 4.8
Crushing 4.8
facial droop 4.7
masculinization 3.7
auditory hallucination 3.7
male subfertility 3.7
hot flashes 3.7
body pain 3.6
dark urine 3.6
adenitis 3.6
livedo 3.6
Physical findings 3.3
meningism 3.3
hyperacusis 3.2
sore throat 3.1
loss of balance 2.9
rhinorrhea 2.9
Halo 2.9
wheezing 2.8
otalgia 2.7
physical appearance 2.7
Catch 2.7
POA 2.7
menopausal symptoms 2.6
hyperemesis gravidarum 2.6
Fluctuation 2.5
hot flushes 2.4
sneezing 2.4
nasal discharge 2.3
groin pain 2.1
more...
Drug
Drostanolone 10.7
Diflorasone diacetate 10.1
Trimegestone 9.7
Squalamine lactate 9.7
Diflorasone 9.7
Ultravate 9.4
Kaempherol 9.1
Winstrol 9.1
Pregnenolone 8.4
Asoprisnil 8.1
Zemplar 8.1
Dramamine 8.0
Dexamethasone acetate 7.6
Equilin 7.4
Aromasin 7.3
Tibolone 7.2
Sincalide 7.2
Lipidex 7.1
Drospirenone 7.1
Imidan 7.1
Deflazacort 6.9
Potassium canrenoate 6.8
Compound 15 6.8
Implanon 6.7
R1881 6.7
Cellcept 6.7
Cellcept 6.7
DHT 6.6
DHT 6.5
Dienogest 6.5
Dihydrotestosterone 6.5
Dutasteride 6.5
2-Methoxyestradiol 6.3
Ortho Tri-Cyclen 6.3
Mevastatin 6.3
Estrogens 6.2
Finasteride 6.1
Sinefungin 5.9
Estriol 5.9
Gestodene 5.9
more...
Enzyme
3(17)alpha-hydroxysteroid dehydrogenase 9.1
2-deoxyglucose-6-phosphate phosphatase 8.7
methylsterol monooxygenase 8.7
7alpha-hydroxysteroid dehydrogenase 8.7
5-DES 8.5
17-ketoreductase 7.7
steroid 5-alpha-reductase 7.7
steroid sulfotransferase 7.7
CYP39A1 7.5
CYP7B1 7.3
SMT2 7.3
11beta-hydroxysteroid dehydrogenase 7.3
20alpha-hydroxysteroid dehydrogenase 7.1
3alpha-hydroxysteroid dehydrogenase 7.0
steroid isomerase 6.9
5alpha-reductase 6.9
5alpha-reductase 6.9
camphor hydroxylase 6.9
steroid 17alpha-hydroxylase 6.8
SOAT 6.7
3beta-hydroxysteroid dehydrogenase 6.6
methionine decarboxylase 6.5
5beta-reductase 6.5
17beta-HSD 6.5
HSD 6.4
GGGT 6.4
17beta-HSD 6.4
ecdysone 20-monooxygenase 6.3
CYP8B1 6.2
squalene-hopene cyclase 5.8
21-hydroxylase 5.8
cytochrome P-450scc 5.7
DHAD 5.7
7-dehydrocholesterol reductase 5.6
leishmanolysin 5.5
cholesterol oxidase 5.5
cycloartenol synthase 5.4
estrogen sulfotransferase 5.4
estrogen sulfotransferase 5.4
GPI-specific phospholipase C 5.3
more...
Compound
Pregnenolone acetate 11.7
C28H44O6 11.7
pregnane-3,17,20-triol 11.7
C28H44O6 11.7
17beta-Hydroxyandrost-4-ene-3,11-dione 11.7
21-Fluoroprogesterone 11.7
cholestane-2,3-diol 11.7
Dimethyltestosterone 11.7
allyl diethyl phosphate 11.7
(1-aminocyclohexyl)methanol 11.7
Pyridine-sulfur trioxide complex 11.7
pregn-2-en-20-one 11.7
3-(4-(bis(2-chloroethyl)amino)phenoxy)propanoic acid 11.7
17-hydroxyandrost-4-en-3-one 11.7
Methylestradiol 10.7
3-hydroxypregnane-11,20-dione 10.7
3-hydroxypregnane-11,20-dione 10.7
3-methoxyestra-1,3,5(10)-trien-17-one 10.7
6-Oxoestriol 10.7
Hellebrin 10.7
Polypodine B 10.7
21-Hydroxypregnenolone 10.7
C21H30O 10.7
17-oxoestra-1,3,5(10)-trien-3-yl 10.7
Inokosterone 10.7
Inokosterone 10.7
Uzarigenin 10.7
17-oxoestra-1,3,5(10)-trien-3-yl 10.7
methyl (triphenylphosphoranylidene)acetate 10.7
16beta-Methylprogesterone 10.7
methyl (triphenylphosphoranylidene)acetate 10.7
C8H12O2 10.7
Cremophor-El 10.7
2-Methoxyestrone 10.7
Dibutyltin oxide 10.7
Cholesterol myristate 10.7
Inokosterone 10.7
estra-1,3,5(10)-trien-17-one 10.5
androst-4-en-3-one 10.5
Trilobolide 10.4
more...