Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C0338671 (
Steroids
)
9,479
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
The effect of estradiol and progesterone on the activity of 3 regulatory enzymes of glycolysis (hexokinase, phosphofructokinase and
pyruvate kinase
) in the brain of female rats was studied in the initial phase of hormonal action.
Steroids
were capable of modifying epileptic activity caused by pentetrazol, the action of estradiol being epileptogenic, that of progesterone anticonvulsant. Hormone action modifying epileptic activity, probably results from changes in intracellular metabolism and from changes in electrogenesis of nerve cells, the second mechanism being predominant.
...
PMID:[Modifying action of estradiol and progesterone on epileptic activity of the rat brain]. 252 61
