Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C0338671 (
Steroids
)
9,479
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
The nervous and immune systems are shown to be interrelated.
Steroids
inhibit both regeneration and the immune response.
Crushing
injuries enhance regeneration. A synthesis of these apparently unrelated phenomena is formulated into an immune hypothesis of regeneration.
Steroids
, in suppressing the immune response, decrease lymphokine production and the subsequent stimulation of nerve cell regeneration.
Crushing
injuries to nerve fibers cause nerve protein to become antigenic, thereby eliciting the production of "non-toxic" antibodies, which paradoxically protect the nerve fibers from immune attack and cause an augmented lymphokine production and subsequent nerve cell regeneration.
...
PMID:The role of the immune system in central nervous system regeneration (theoretical considerations). 339 87
