Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C0314719 (
dry eye
)
2,625
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
lacrimal
402
Sep
128
mucin
112
Mol
77
cytokine
69
TNF
52
IL-6
44
She
42
lamp
40
CD4
39
SS-A
34
IFN
31
lactoferrin
30
collagen
29
IL-17
28
lysozyme
26
rheumatoid factor
25
SSA
25
interferon
24
SSB
23
MUC5AC
22
SS-B
22
tumor necrosis factor
21
MMP-9
18
IL-8
17
lymphoid
17
chemokine
17
ATP
17
P2Y2
17
insulin
13
NOD
13
HLA-DR
13
MUC16
13
matrix metalloproteinase
12
gut
12
AQP5
12
CD8
12
MUC1
11
glycoprotein
11
HLA
10
caspase-3
10
lacritin
9
IgA
9
IgE
9
P2X
9
strabismus
9
MMP9
9
lectin
9
IL-13
9
IL-10
9
MRI
9
substance P
8
Cytokine
8
NLRP3
8
TSP
8
IL-1
8
p38
8
endoplasmic reticulum
8
polypeptide
8
IL-2
8
IL-4
8
Pseudomonas
8
fibronectin
8
corneal dystrophy
7
ANA
7
OCT
7
MUC4
7
interleukin-6
7
MHC
7
superoxide dismutase
7
tear lipocalin
7
clusterin
6
p65
6
TNF-alpha
6
cyclooxygenase
6
peroxidase
6
interferon gamma
6
B10
6
Ki-67
6
epidermal growth factor
6
more...
Disease
cornea
324
xerostomia
236
conjunctiva
172
dry eye syndrome
135
autoimmune disease
131
glaucoma
128
keratoconjunctivitis sicca
123
keratitis
107
cataract
105
Sjogren's syndrome
86
conjunctivitis
71
blepharitis
70
rheumatoid arthritis
65
graft-versus-host disease
60
diabetes
59
Cornea
56
Cornea
56
Meibomian gland dysfunction
53
uveitis
52
keratopathy
50
eye disease
48
intraocular pressure
46
cancer
44
macular degeneration
44
epiphora
43
blindness
42
systemic lupus erythematosus
41
keratoconjunctivitis
40
arthritis
36
diabetic retinopathy
33
pemphigoid
30
allergic conjunctivitis
30
Stevens-Johnson syndrome
30
tumor
28
pruritus
28
prolapse
27
vasculitis
26
xerophthalmia
26
cold
26
sicca syndrome
25
lymphoma
25
depression
24
Anterior
24
retinopathy
23
corneal ulcer
23
rosacea
22
diplopia
22
keratoconus
20
myopia
20
systemic disease
20
Syndrome
19
strabismus
19
neuropathy
19
astigmatism
19
PSS
18
lupus
17
aqueous humor
17
sarcoidosis
16
anterior uveitis
16
lagophthalmos
16
sialadenitis
15
connective tissue disease
15
ectropion
15
dysphagia
14
asthma
14
Parkinson's disease
14
scleritis
14
blepharoconjunctivitis
13
NOD
13
lupus
13
cystic fibrosis
13
scleroderma
12
chronic conjunctivitis
12
skin disease
12
lymphadenopathy
12
peripheral neuropathy
12
chronic pain
11
episcleritis
11
dehydration
11
psoriasis
11
more...
Symptom
dry eye
2625
discomfort
163
discomfort
159
pain
144
fatigue
53
photophobia
44
blurred vision
41
thinning
32
anesthesia
32
headache
27
blepharospasm
26
arthralgia
24
weakness
21
eye pain
16
cough
14
spasm
12
myalgia
11
dry skin
9
erythema
9
constipation
8
paresis
7
dystonia
7
nausea
7
dizziness
6
chronic cough
6
numbness
6
Ill
5
dyspnea
5
ophthalmoplegia
4
exertional dyspnea
4
regurgitation
4
back pain
4
shortness of breath
4
sleepiness
4
abdominal pain
3
dysesthesia
3
pleuritic chest pain
3
diarrhea
3
asthenia
3
hyperacusis
3
twitching
3
vomiting
3
bloodshot eyes
3
redness of the eyes
3
neck pain
2
menopausal symptoms
2
paresthesia
2
syncope
2
decreased appetite
2
tinnitus
2
torticollis
2
epigastric pain
2
tremor
2
insomnia
2
ataxia
2
cracked lips
2
joint stiffness
2
hoarseness
2
facial pain
2
Bell's phenomenon
2
functional recovery
2
eye discharge
2
rhinorrhea
2
spasticity
2
polydipsia
1
paraparesis
1
chest pain
1
vestibulitis
1
apathy
1
bladder pain
1
splenomegaly
1
stomach pain
1
stinging eye
1
loss of taste
1
nausea and vomiting
1
angina
1
abnormal taste
1
dry throat
1
pelvic pain
1
sialectasis
1
more...
Drug
Dermatol
16
Fluorescein
12
Diphenhydramine
10
balanced salt solution
10
Fluorescein
10
Rebamipide
9
Neoral
9
Asthma
8
IL-2
8
Pilocarpine
4
Timolol
4
CSF
4
Azithromycin
4
Monit
4
Cevimeline
4
Retinoic acid
4
Loteprednol etabonate
3
Honey
3
vitamin E
3
ROS
3
Rituximab
3
Gel
3
MAP
3
ETS
3
Menthol
3
Alliance
2
Dial
2
Leaf
2
lysine
2
CTT
2
Botox
2
Scopolamine
2
Albumin
2
Travoprost
2
ROC
2
DHT
2
Bayer
2
Isotretinoin
2
DHT
2
p75
2
Vitamin E
2
Clopidogrel
2
Tacrolimus
2
Award
2
Sodium hyaluronate
2
OTC
1
Dasatinib
1
Mizoribine
1
Biopolymers
1
Tafluprost
1
Docetaxel
1
CFS
1
Diclofenac sodium
1
Vitamin A
1
Tocilizumab
1
IFN-gamma
1
Evoxac
1
Nitric Oxide
1
CCL
1
Naltrexone hydrochloride
1
Gabapentin
1
Indomethacin
1
Retinoic Acid
1
Methylene blue
1
Plavix
1
NOV
1
Escitalopram
1
Estrogens
1
Acuvue
1
Modafinil
1
Aloe
1
Cellulose acetate
1
ascorbate
1
Asn
1
Tranilast
1
Deferasirox
1
Polyacrylic acid
1
-deoxyadenosine
1
CAM
1
Lisdexamfetamine dimesylate
1
more...
Enzyme
lysozyme
26
mitogen-activated protein kinase
14
superoxide dismutase
8
peroxidase
8
focal adhesion kinase
8
caspase-3
7
ERK
6
caspase-1
6
MMP
5
protein kinase
5
calcineurin
5
phospholipase C
4
adenylate cyclase
4
ACS
4
catalase
4
glutathione peroxidase
4
TSP-1
4
botulinum neurotoxin
4
hexosaminidase
3
MIP
3
aconitase
3
collagenase
3
caspase-8
3
ceruloplasmin
3
trypsin
3
NQO1
3
lipase
3
transglutaminase
2
aldehyde dehydrogenase
2
matrix metalloproteinase 9
2
aldehyde dehydrogenase
2
endonuclease
2
lactate dehydrogenase
2
aldehyde dehydrogenase
2
xanthine dehydrogenase
2
aldehyde dehydrogenase
2
carbonic anhydrase
2
peroxiredoxin
2
MMP-3
2
xanthine oxidase
2
lipoxygenase
2
tryptase
2
phosphoinositide 3-kinase
2
aldehyde dehydrogenase
2
MEK
2
cathepsin S
2
neuraminidase
1
PARP
1
chondroitinase
1
PAM
1
proteinase-3
1
PDK1
1
arginase
1
glutathione S-transferase
1
ACE
1
phospholipase D
1
arylsulfatase A
1
aspartate aminotransferase
1
NAT
1
indoleamine 2,3-dioxygenase
1
fatty acid elongase
1
GRK2
1
MTD
1
luciferase
1
DNase
1
caspase-9
1
proteasome
1
phosphodiesterase
1
alkaline phosphatase
1
phospholipase A2
1
SPC
1
GSK
1
Alternating
1
APC
1
succinate dehydrogenase
1
ornithine transcarbamylase
1
enolase
1
acyl-CoA synthetase
1
plasmin
1
sulfatase
1
more...
Compound
Clin
219
Dec
163
water
74
sodium
55
TNF
52
oxygen
48
DNA
29
hyaluronic acid
27
Cyclosporine
25
calcium
24
NIDA
18
retinoic acid
18
ATP
18
phenol
17
Rose Bengal
13
phosphate
13
Diphenhydramine
10
Allergan
10
Pac
9
PEG
9
acetate
9
sulfate
9
iodine
8
uridine
8
ANA
7
ANA
7
selenium
7
salt
7
nitrogen
7
vitamin D
7
iron
7
urea
7
glucose
7
Benzalkonium chloride
6
pyrimidine
6
hydrogen
6
pyrimidine
6
8-OHdG
6
serine
6
potassium
6
nitric oxide
6
cAMP
5
TMA
5
ammonium
5
creatinine
5
retinol
5
FK506
5
UTP
5
Trehalose
5
cysteine
5
TOF
5
Salt
5
TMA
5
SDS
5
Curcumin
5
Estrogen
5
silicon
5
Pilocarpine
4
Lip
4
GSH
4
ACS
4
ASC
4
adenosylmethionine
4
PEG
4
acrylic acid
4
Adrenal
4
methionine
4
ACS
4
GlcNAc
4
formaldehyde
4
TEM
4
CO2
4
Azithromycin
4
formaldehyde
4
Timolol
4
DHA
4
tetraphosphate
4
MTT
4
GSH
4
Progesterone
3
more...