Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0314719 (dry eye)
2,625 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
lacrimal 402
Sep 128
mucin 112
Mol 77
cytokine 69
TNF 52
IL-6 44
She 42
lamp 40
CD4 39
SS-A 34
IFN 31
lactoferrin 30
collagen 29
IL-17 28
lysozyme 26
rheumatoid factor 25
SSA 25
interferon 24
SSB 23
SS-B 22
MUC5AC 22
tumor necrosis factor 21
MMP-9 18
P2Y2 17
chemokine 17
IL-8 17
ATP 17
lymphoid 17
HLA-DR 13
NOD 13
insulin 13
MUC16 13
gut 12
CD8 12
AQP5 12
matrix metalloproteinase 12
glycoprotein 11
MUC1 11
HLA 10
more...
Disease
cornea 324
xerostomia 236
conjunctiva 172
dry eye syndrome 135
autoimmune disease 131
glaucoma 128
keratoconjunctivitis sicca 123
keratitis 107
cataract 105
Sjogren's syndrome 86
conjunctivitis 71
blepharitis 70
rheumatoid arthritis 65
graft-versus-host disease 60
diabetes 59
Cornea 56
Cornea 56
Meibomian gland dysfunction 53
uveitis 52
keratopathy 50
eye disease 48
intraocular pressure 46
macular degeneration 44
cancer 44
epiphora 43
blindness 42
systemic lupus erythematosus 41
keratoconjunctivitis 40
arthritis 36
diabetic retinopathy 33
Stevens-Johnson syndrome 30
allergic conjunctivitis 30
pemphigoid 30
pruritus 28
tumor 28
prolapse 27
xerophthalmia 26
cold 26
vasculitis 26
sicca syndrome 25
more...
Symptom
dry eye 2625
discomfort 163
discomfort 159
pain 144
fatigue 53
photophobia 44
blurred vision 41
anesthesia 32
thinning 32
headache 27
blepharospasm 26
arthralgia 24
weakness 21
eye pain 16
cough 14
spasm 12
myalgia 11
dry skin 9
erythema 9
constipation 8
paresis 7
dystonia 7
nausea 7
dizziness 6
numbness 6
chronic cough 6
Ill 5
dyspnea 5
ophthalmoplegia 4
exertional dyspnea 4
regurgitation 4
back pain 4
sleepiness 4
shortness of breath 4
dysesthesia 3
abdominal pain 3
pleuritic chest pain 3
bloodshot eyes 3
vomiting 3
hyperacusis 3
more...
Drug
Dermatol 16
Fluorescein 12
Fluorescein 10
Diphenhydramine 10
balanced salt solution 10
Neoral 9
Rebamipide 9
Asthma 8
IL-2 8
Retinoic acid 4
Azithromycin 4
Pilocarpine 4
CSF 4
Cevimeline 4
Monit 4
Timolol 4
Rituximab 3
Loteprednol etabonate 3
vitamin E 3
MAP 3
Honey 3
Gel 3
Menthol 3
ROS 3
ETS 3
Vitamin E 2
Award 2
p75 2
Tacrolimus 2
ROC 2
Dial 2
Scopolamine 2
Leaf 2
Botox 2
Albumin 2
Bayer 2
Travoprost 2
Alliance 2
DHT 2
lysine 2
more...
Enzyme
lysozyme 26
mitogen-activated protein kinase 14
focal adhesion kinase 8
superoxide dismutase 8
peroxidase 8
caspase-3 7
caspase-1 6
ERK 6
protein kinase 5
MMP 5
calcineurin 5
phospholipase C 4
catalase 4
ACS 4
TSP-1 4
adenylate cyclase 4
botulinum neurotoxin 4
glutathione peroxidase 4
ceruloplasmin 3
collagenase 3
MIP 3
caspase-8 3
hexosaminidase 3
trypsin 3
NQO1 3
aconitase 3
lipase 3
transglutaminase 2
phosphoinositide 3-kinase 2
lactate dehydrogenase 2
aldehyde dehydrogenase 2
peroxiredoxin 2
aldehyde dehydrogenase 2
MMP-3 2
endonuclease 2
xanthine dehydrogenase 2
aldehyde dehydrogenase 2
carbonic anhydrase 2
aldehyde dehydrogenase 2
xanthine oxidase 2
more...
Compound
Clin 219
Dec 163
water 74
sodium 55
TNF 52
oxygen 48
DNA 29
hyaluronic acid 27
Cyclosporine 25
calcium 24
ATP 18
NIDA 18
retinoic acid 18
phenol 17
phosphate 13
Rose Bengal 13
Allergan 10
Diphenhydramine 10
sulfate 9
Pac 9
acetate 9
PEG 9
iodine 8
uridine 8
urea 7
salt 7
selenium 7
nitrogen 7
ANA 7
iron 7
ANA 7
glucose 7
vitamin D 7
8-OHdG 6
pyrimidine 6
nitric oxide 6
hydrogen 6
potassium 6
pyrimidine 6
serine 6
more...