Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C0314719 (
dry eye
)
2,625
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
PDE4
inhibitors have the potential to alleviate the symptoms and underlying inflammation associated with
dry eye
. Disclosed herein is the development of a novel series of water-soluble
PDE4
inhibitors. Our studies led to the discovery of coumarin 18, which is effective in a rabbit model of
dry eye
and a tear secretion test in rats.
...
PMID:Water-soluble PDE4 inhibitors for the treatment of dry eye. 2037 48
