Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0311277 (abdominal obesity)
 2,792 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Aseries of 143 new outpatients who had had chronic low back pain for longer than 3 months, with neither a positive straight leg raise test nor radiographic abnormality including lumbar spondylosis, were treated for 4 weeks with a traditional lumbosacral corset or one with a front-to-back tensile band (extensile corset). Randomization was performed according to birth date. Radiographs were used to analyze the change in sacral inclination angle with and without the respective corset. Central obesity subgroups consisted of men with a waist/hip ratio (W/H) of > or =90% and women with a W/H ratio of > or = 80%. Quebec Back Pain Disability Scale scores were measured at baseline and at 4 weeks. The mean changes in sacral inclination were +3.8 degrees +/- 5.4 degrees in the extensile corset group ( n = 72) and -2.6 degrees +/- 4.6 degrees in the traditional corset group ( n = 71). Thus, the extensile corset had a mechanical effect opposite to that of the traditional corset. Participants without central obesity who were treated with the extensile corset ( n = 30) demonstrated significant improvement compared to participants with the traditional corset ( n = 33) ( P = 0.034). Central obesity should be considered when recommending corsets for patients with chronic muscular low back pain.
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PMID:Impact of waist/hip ratio on the therapeutic efficacy of lumbosacral corsets for chronic muscular low back pain. 1248 67

Both low back pain (LBP) and obesity are common public health problems, yet their relation remains controversial. The aim of this study was to investigate the associations between weight-related factors and the prevalence of LBP in young adults in Finland. Participants in the ongoing Cardiovascular Risk in Young Finns Study aged 24-39 years were included (N = 2,575). In 2001, 31.2% of men and 39.5% of women reported LBP with recovery within a month or recurrent or continuous pain during the preceding 12 months. For women only, those with higher body mass index, waist circumference, hip circumference, waist-to-hip ratio, serum leptin level, and C-reactive protein level showed an increased prevalence of LBP. With all weight-related factors in the model, only waist circumference was related to LBP in women. For women, the odds ratios of LBP were 1.2 (95% confidence interval: 0.8, 1.8) for a waist circumference of 80-87.9 cm and 1.8 (95% confidence interval: 1.0, 3.2) for a waist circumference of > or =88 cm compared with a waist circumference of <80 cm. This association was independent of C-reactive protein, leptin, and adiponectin levels. The authors' findings in a relatively young population suggest that abdominal obesity may increase the risk of LBP in women.
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PMID:The association between obesity and the prevalence of low back pain in young adults: the Cardiovascular Risk in Young Finns Study. 1833 1