Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0279530 (bone cancer)
 1,036 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
ERG/EWS 14.9
C3orf35 13.9
LMNA protein 12.9
brachyury protein 12.3
ECHDC2 12.3
Neurensin-2 12.1
TSGA14 12.1
TUT1 11.7
T-cell death-associated gene 8 11.2
SUV420H2 11.2
antioxidant protein 1 11.1
DNAJA4 11.0
bone-derived growth factor 11.0
SCN7A 11.0
TRIM46 10.7
PHF11 10.7
CLL1 10.4
KPNA3 10.4
C-X-C chemokine receptor type 5 10.4
ROCK2 protein 10.4
MMP28 10.3
Visinin-like protein 1 10.3
DIF-3 10.2
Calpain-2 10.1
MTBP 10.1
EDG2 10.1
EPB41 10.1
TEAD2 10.1
RASSF10 10.0
RARRES2 9.9
SKA2 9.9
KIF17 9.8
MRC2 9.8
RASSF2 9.7
Stathmin 1 9.7
claspin 9.6
CDL 9.5
HMGB3 9.5
EphB1 9.5
CTNND1 9.4
NPTX2 9.4
sodium-potassium-chloride cotransporter 9.4
NSD3 9.3
UBF1 9.3
MAPK7 9.3
NET-1 9.3
FGF12 9.3
UEV1A 9.2
LPCAT2 9.2
MRTF-B 9.2
PPP1R15A 9.2
peroxiredoxin 4 9.1
osteosarcoma 9.1
NGD 9.1
stem cell growth factor 9.0
SHMT2 9.0
Protease-activated receptor 2 9.0
NOT1 9.0
MLK2 9.0
Suppressor of cytokine signaling 3 8.9
claudin-8 8.9
Annexin A3 8.9
Voltage-dependent anion channel 8.8
TCRD 8.8
FLI1 8.7
cytosolic phosphoprotein 8.7
CTHRC1 8.6
MEPE 8.6
ribosomal S6 protein kinase 8.6
E2 antigen 8.6
HOS 8.5
RAB5 8.4
TNAP 8.4
tankyrase 2 8.4
KLK7 8.4
SLC1A1 8.4
XLMR 8.4
zinc finger E-box binding homeobox 1 8.3
SHMT1 8.3
Calcium/calmodulin-dependent protein kinase II 8.3
protease-activated receptor 4 8.3
GTF2I 8.3
SIGIRR 8.2
EWS 8.2
secreted frizzled-related protein 1 8.2
EphB2 8.2
HOXB7 8.1
KID 8.1
Walker 8.1
Forkhead box M1 8.1
excision repair protein 8.1
FOXF1 8.0
mitofusin 1 8.0
MTAP 8.0
BMP1 8.0
Pigment epithelium-derived factor 8.0
R-cadherin 8.0
HMGB2 7.9
Kv3.4 7.9
BUB1B 7.9
PTH1 7.9
P2X3 7.8
RPA1 7.8
SP7 7.8
DSR 7.8
CHEK1 7.8
glutamate carboxypeptidase II 7.8
SPS1 7.8
Wnt inhibitory factor-1 7.7
pycnodysostosis 7.7
ATG3 7.7
extracellular signal-regulated kinase 5 7.7
LPA1 7.7
hephaestin 7.7
DNA ligase III 7.7
secreted phosphoprotein 1 7.7
KIT protein 7.6
SOX5 7.6
FLI 7.6
Li-Fraumeni syndrome 7.6
methylthioadenosine phosphorylase 7.6
P2RX7 7.5
FIP200 7.5
parathyroid hormone receptor 7.5
SNS 7.5
OSX 7.4
Runt-related transcription factor 2 7.4
OMG 7.4
KIP 7.3
Transforming growth factor-alpha 7.3
tissue inhibitor of metalloproteinase-3 7.3
tissue inhibitor of metalloproteinases-2 7.3
Ras-related protein 7.3
endonuclease G 7.3
IGFBP1 7.2
collagenase-3 7.2
NR2B 7.2
proteinase-activated receptor-2 7.1
preprodynorphin 7.1
EWSR1 7.1
RASSF1 7.1
receptor protein tyrosine kinase 7.1
CASP9 7.1
RAMP1 7.1
insulin-like growth factor binding protein-4 7.1
PEDF 7.1
Janus kinase 1 7.1
TUBB3 7.1
CX3CR1 7.0
Ubc13 7.0
SETD2 7.0
artemin 7.0
HSP70-1 7.0
CSN5 7.0
Fli-1 6.9
mGluR3 6.9
MMP7 6.9
E2F2 6.9
KCNQ3 6.9
CC-chemokine 6.9
TCI 6.8
RANK 6.8
P2X7 6.8
RAL 6.8
CD99 6.8
mGlu1 6.7
transient receptor potential vanilloid 1 6.7
PDE4B 6.7
NRSF 6.7
PTD 6.7
zyxin 6.7
oncogene) 6.7
ALPL 6.7
REDD1 6.7
PRKAR1A 6.6
CGRP 6.6
RECQL4 6.6
neurturin 6.6
P2X2 6.6
Cyclin-dependent kinase 5 6.6
Nav1.7 6.6
CCNB1 6.6
DRG 6.5
KCC2 6.5
caspase 2 6.5
CCND2 6.5
calcium/calmodulin-dependent protein kinase II 6.5
PBD 6.4
E2F3 6.4
carboxypeptidase E 6.4
SMARCA4 6.4
RANTES) 6.4
SMO 6.4
NCS-1 6.4
cyclin-dependent kinase inhibitor p27 6.3
steroid receptor coactivator 6.3
dynamin-related protein 1 6.3
silencer element 6.3
RANKL 6.3
MMP2 6.3
PDGFRB 6.3
BIRC5 6.3
PAR2 6.3
AIF 6.3
CCR2 6.3
PTCH1 6.2
proenkephalin 6.2
TIMP3 6.2
WWOX 6.2
NaN 6.2
CASP8 6.2
pigment epithelium-derived factor 6.2
CDC25A 6.2
PTK 6.2
CDK7 6.2
endocytic receptor 6.1
RUNX2 6.1
activating transcription factor 3 6.1
glutamate receptor subunit 6.1
CXCR3 6.1
sirtuin 1 6.1
ROCK2 6.1
serine hydroxymethyltransferase 6.1
TRPV1 6.1
Metalloproteinase 6.1
Kv1.4 6.1
FGF1 6.0
GPR30 6.0
member 1 6.0
glycine decarboxylase 6.0
TRIM 6.0
Bloom syndrome 6.0
fractalkine 6.0
osteoprotegerin 6.0
non-protein coding 6.0
ionized calcium-binding adapter molecule 6.0
IPL 6.0
MCL1 5.9
NMDAR1 5.9
OPG 5.9
cIAP1 5.9
KCNQ2 5.9
CB2 5.9
opioid receptor 5.9
Musashi-1 5.9
GDNF 5.9
ataxia telangiectasia mutated 5.9
XIAP 5.9
Apaf-1 5.9
CD147 5.8
HMGB1 5.8
vesicular GABA transporter 5.8
pRb 5.8
ATF3 5.8
CDK9 5.8
TRPA1 5.8
CD70 5.8
WIN 5.8
CXCL1 5.8
RIPK3 5.8
histone deacetylase 1 5.8
tyrosine protein kinase 5.8
Transglutaminase 5.7
polo-like kinase 1 5.7
Kv4.3 5.7
CCS 5.7
endothelin A receptor 5.6
CC chemokine 5.6
mu opioid receptor 5.6
BAM 5.6
RUNX3 5.6
G9a 5.6
TGFB1 5.6
pyruvate dehydrogenase kinase 5.6
ROCK1 5.6
D2R 5.5
mGluR5 5.5
CTNNB1 5.5
PAR-2 5.5
Notch2 5.5
Nanog 5.5
frizzled 5.5
dynorphin 5.5
TORC1 5.5
HAP 5.4
Osteocalcin 5.4
IAP 5.4
NF-H 5.4
C-X-C chemokine receptor type 4 5.4
MMP9 5.4
prodynorphin 5.4
c-FLIP 5.4
NF2 5.4
REST 5.4
NMDA receptor subunit 5.4
TFT 5.4
RASSF1A 5.4
pro-apoptotic protein 5.4
tyrosine kinase 3 5.4
MT1-MMP 5.3
MMP13 5.3
cAMP-response element 5.3
Werner syndrome 5.3
CH1 5.3
nucleolar protein 5.3
TRPV4 5.3
STAT4 5.3
TNT 5.3
protein X 5.3
BAP 5.3
GDC 5.2
X-linked inhibitor of apoptosis protein 5.2
LMNA 5.2
E2F1 5.2
SREBP-1c 5.2
Ku80 5.2
FLICE 5.2
c-Src 5.2
merlin 5.2
MMP1 5.2
stathmin 5.2
osterix 5.2
NR1 5.2
LSD1 5.2
norepinephrine transporter 5.2
sphingosine kinase 5.2
CXCR2 5.2
DNA repair protein 5.1
CXCR5 5.1
delta opioid receptor 5.1
glial fibrillary acidic protein 5.1
Bak 5.1
ABS 5.1
CFA 5.1
IRS-2 5.1
BMP2 5.1
receptor kinase 5.1
protein-tyrosine kinase 5.1
Histone deacetylase 5.1
nerve growth factor receptor 5.1
metastasis suppressor 5.0
LXR 5.0
p120 5.0
CXCL13 5.0
YAP 5.0
CaMKII 5.0
connexin 43 5.0
transmembrane receptor 5.0
bone) 5.0
GLP 5.0
TNF-a 5.0
Plasmin 5.0
nucleotide pyrophosphatase 5.0
periostin 5.0
PUMA 5.0
FLIP 5.0
high mobility group box 1 5.0
RAD51 5.0
ULK1 4.9
MDP 4.9
C30 4.9
NKCC1 4.9
nerve growth factor 4.9
CXCL12 4.9
MCT 4.9
tartrate-resistant acid phosphatase 4.9
MSP 4.9
RIPK1 4.9
HDAC2 4.9
SP1 4.9
DMS 4.9
Smac 4.9
Cx43 4.9
GATA4 4.9
Iba1 4.8
Janus kinase 2 4.8
LAMP-1 4.8
CIP 4.8
CDKN1A 4.8
translocator protein 4.8
PID 4.8
non-active 4.8
phosphatase and tensin homolog 4.8
P16 4.8
p21 protein 4.8
presenilin 1 4.8
ALK5 4.8
Ku70 4.8
TAK 4.8
peroxisome proliferator-activated receptor alpha 4.8
amphiregulin 4.8
HDAC1 4.8
IL-33 4.7
Hes1 4.7
ABCC1 4.7
Mcl-1 4.7
TNFR2 4.7
JNK1 4.7
AR protein 4.7
cannabinoid receptor 4.7
glial cell line-derived neurotrophic factor 4.7
TAZ 4.7
fatty acid amide hydrolase 4.7
version 3 4.7
Smad3 4.7
PAF receptor 4.7
CD133 4.7
intermediate filament protein 4.7
CAR 4.7
IL-11 4.6
sclerostin 4.6
OFQ 4.6
NOTCH1 4.6
matrix metalloprotease 4.6
neurofilament protein 4.6
signal transducer and activator of transcription 3 4.6
RIP 4.6
PI3K 4.6
FADD 4.6
erm 4.6
rhabdomyosarcoma 4.5
53BP1 4.5
DLD 4.5
CCL2 4.5
p38 mitogen-activated protein kinase 4.5
MMP-9 4.5
ATF4 4.5
visfatin 4.5
ERK 4.5
osteogenic 4.5
ERG 4.5
IL1B 4.5
LC3B 4.5
metabotropic glutamate receptor 4.5
NRK 4.5
FOS 4.5
Proteasome 4.4
amyloid protein 4.4
NSE 4.4
urocortin 4.4
lysyl oxidase 4.4
PMS 4.4
NAC 4.4
PKA 4.4
lamin A 4.3
AKT 4.3
VIM 4.3
IL-18 4.3
CAL 4.3
CXCL10 4.3
ZEB1 4.3
Parathyroid hormone 4.3
COL1A1 4.3
Smad1 4.3
PD-1 4.3
solute carrier 4.3
cyclin dependent kinase 4.3
tropomyosin 4.3
RAR 4.2
C/EBP homologous protein 4.2
adrenomedullin 4.2
SOX9 4.2
Bax protein 4.2
Kir6.2 4.2
ST2 4.2
calcitonin 4.2
catenin 4.2
BAX 4.2
RNA binding protein 4.2
NS5 4.2
extracellular signal-regulated kinase 4.2
connexin 4.2
RNase III 4.1
SIRT1 4.1
JAK1 4.1
protein kinase B 4.1
Aurora-A 4.1
GAP-43 4.1
Fibroblast growth factor 4.1
matrix metalloproteinase 4.1
histone methyltransferase 4.1
PARP 4.1
p73 4.1
monocyte chemoattractant protein 4.1
RB1 4.1
MMP-2 4.1
CXCL9 4.1
PERK 4.1
NR2A 4.1
RCN 4.1
heat shock protein 90 4.1
ECM 4.1
AS1 4.0
MMP 4.0
TCP 4.0
Brain-derived neurotrophic factor 4.0
c-Jun 4.0
Yes 4.0
CXC chemokine 4.0
ATF 4.0
NGF 4.0
SET 4.0
adenomatous polyposis coli 4.0
chemokine 4.0
poly (ADP-ribose) polymerase 4.0
monocyte chemoattractant protein-1 4.0
PBS 4.0
ezrin 4.0
SRY 3.9
syndecan 3.9
p38MAPK 3.9
RANTES 3.9
4E-BP1 3.9
NKG2D 3.9
immunoglobulin superfamily 3.9
GTP-binding protein 3.9
CBT 3.9
Rho kinase 3.9
G-protein-coupled receptor 3.9
MET 3.9
MEK 3.9
bone morphogenetic protein 3.8
transmembrane glycoprotein 3.8
EZH2 3.8
PP1 3.8
Endothelin-1 3.8
LC3 3.8
cyclin-dependent kinase inhibitor 3.8
caspase-8 3.8
TIMP-2 3.8
TRAP 3.8
neuronal nitric oxide synthase 3.8
p70 3.8
CD27 3.8
caspase-3 3.7
Bid 3.7
TLR4 3.7
PML 3.7
MSC 3.7
c-fms 3.7
F10 3.7
annexin V 3.7
MCM 3.7
myogenin 3.7
neurotrophic factor 3.7
caspase-9 3.7
proopiomelanocortin 3.7
proteasome inhibitor 3.7
connective tissue growth factor 3.7
RNA-binding protein 3.7
Cyclin 3.7
p16INK4a 3.7
HCN 3.7
dopamine D2 receptor 3.7
MIB 3.7
HDAC 3.7
CB1 3.6
c-Myc 3.6
mouse) 3.6
cathepsin 3.6
GLP-1 3.6
bax 3.6
bone sialoprotein 3.6
p38 MAP kinase 3.6
PKG 3.6
PARP-1 3.6
HGF 3.6
glutamate transporter 3.6
kinesin 3.6
cytokine receptor 3.6
parathyroid hormone-related protein 3.6
G-CSF 3.6
UTR 3.6
Cyclin D1 3.6
PKC 3.6
p11 3.5
GRP78 3.5
intercellular adhesion molecule-1 3.5
DNMT1 3.5
histone H4 3.5
p38 3.5
ABCB1 3.5
cyclin-dependent kinase 3.5
survival factor 3.5
CXCR4 3.5
SOX2 3.5
p53 3.5
anti-apoptotic protein 3.5
Janus kinase 3.5
transcriptional repressor 3.5
Bcl-2 3.4
non-Hodgkin's lymphoma 3.4
ATM 3.4
galectin-3 3.4
cadherin 3.4
DNA-dependent protein kinase 3.4
endothelin receptor 3.4
CD117 3.4
PD-L1 3.4
TNF 3.4
RhoA 3.4
GLUT1 3.4
phosphoinositide 3-kinase 3.4
tyrosine phosphatase 3.4
FAK 3.4
CTP 3.4
thymidylate synthase 3.4
calpain 3.4
CDK2 3.4
beach 3.3
FasL 3.3
Rad 3.3
OCT4 3.3
P21 3.3
angiotensin II receptor 3.3
chimeric protein 3.3
glycosyltransferase 3.3
COX-2 3.3
ERK1 3.2
NMDA receptor 3.2
Trypsin 3.2
ATR 3.2
RET 3.2
TRAIL 3.2
IGF-1 3.2
CREB 3.2
TGA 3.2
activin 3.2
sonic hedgehog 3.2
A-T 3.2
sodium channel 3.1
p75 3.1
substance P 3.1
BCL2 3.1
p21 3.1
IL6 3.1
membrane glycoprotein 3.1
galanin 3.1
P2X 3.1
transthyretin 3.1
IL-6 3.1
phosphatidylinositol 3-kinase 3.1
microtubule-associated protein 3.1
granulocyte-macrophage 3.1
Sp1 3.0
macrophage colony-stimulating factor 3.0
topoisomerase I 3.0
histone deacetylase 3.0
THC 3.0
IL-1 3.0
glutamate receptor 3.0
p27 3.0
Ki-67 3.0
H2AX 3.0
CDK4 3.0
alkaline phosphatase 3.0
cytochrome c 3.0
fatty acid synthase 2.9
IL-23 2.9
KIT 2.9
JNK 2.9
insulin-like growth factor 2.9
short form 2.9
STAT3 2.9
MEK1 2.9
TNF receptor 2.9
ALP 2.9
SWI 2.8
DNA-binding protein 2.8
IL-17 2.8
insulin-like growth factor I 2.8
STAT 2.8
PTEN 2.8
histone 2.8
adenosine receptor 2.8
GM-CSF 2.8
nuclear receptor 2.7
neurotensin 2.7
IRS-1 2.7
chemokine receptor 2.7
cyclin E 2.7
receptor tyrosine kinase 2.7
homeobox 2.7
STAT1 2.7
focal adhesion kinase 2.7
metalloprotease 2.7
CAM 2.7
tumor necrosis factor alpha 2.7
survivin 2.7
vitamin D receptor 2.6
p62 2.6
platelet-derived growth factor 2.6
cage 2.6
hedgehog 2.6
kallikrein 2.6
cell adhesion molecule 2.6
SCH 2.6
BRCA2 2.6
PDB 2.6
corticotropin-releasing factor 2.6
vascular endothelial growth factor 2.6
Rho 2.6
mTOR 2.6
interleukin-10 2.6
erbB-2 2.5
histone H3 2.5
ubiquitin ligase 2.5
serine/threonine kinase 2.5
PC-3 2.5
VEGF 2.5
CHOP 2.5
parathyroid hormone 2.5
CEA 2.5
FAD 2.5
FDG 2.5
sit 2.5
osteocalcin 2.4
Tumor necrosis factor 2.4
fur 2.4
methyltransferase 2.4
CD44 2.4
CTX 2.4
ankylosing spondylitis 2.4
tumor necrosis factor 2.4
epidermal growth factor receptor 2.4
CCR5 2.4
neurotrophin 2.4
GSK 2.3
PDGF 2.3
AMPK 2.3
LDL receptor 2.3
MAPK 2.3
plasminogen activator inhibitor-1 2.3
alternatively spliced 2.3
proteasome 2.2
transcriptional activator 2.2
c-kit 2.2
Dictyostelium 2.2
P-glycoprotein 2.2
NOD 2.2
Fas 2.2
Hua 2.2
ionotropic 2.2
PTH 2.2
granulocyte-macrophage colony-stimulating factor 2.2
chronic renal failure 2.2
p65 2.1
AFM 2.1
peroxisome proliferator-activated receptor gamma 2.1
MCP-1 2.1
Boc 2.1
glucose transporter 2.1
desmin 2.1
twist 2.1
transmembrane protein 2.1
GTPase 2.1
collagen 2.1
AMP-activated protein kinase 2.1
phosphoprotein 2.1
prostate-specific antigen 2.0
hole 2.0
SAR 2.0
thymidine kinase 2.0
bcl-2 2.0
metalloproteinase 2.0
E-cadherin 2.0
TLR2 2.0
AML 2.0
nuclear protein 2.0
C18 2.0
HEK 1.9
granulocyte 1.9
TNM 1.9
APC 1.9
antioxidant enzyme 1.9
threonine 1.9
IL-1 beta 1.9
CD20 1.9
anonymous 1.9
MRI 1.8
ACS 1.8
helicase 1.8
B12 1.8
IL-10 1.8
Mol 1.8
all-trans 1.8
peptidase 1.8
Polymerase 1.7
estrogen receptor 1.7
CD45 1.7
vimentin 1.7
endothelin-1 1.7
cytokine 1.7
ROS 1.7
LPS 1.7
membrane-bound 1.7
membrane protein 1.6
plasminogen 1.6
IGF-I 1.6
RNA polymerase II 1.6
TEM 1.6
aromatase 1.6
xenobiotic 1.6
APA 1.5
mitogen-activated protein 1.5
cytochrome 1.5
cyclin 1.5
ubiquitin 1.5
epidermal growth factor 1.5
EPA 1.5
c-fos 1.4
serum albumin 1.4
Men 1.4
IL-8 1.4
interleukin-6 1.4
acid phosphatase 1.3
calmodulin 1.3
C-C 1.2
proliferating cell nuclear antigen 1.2
GTP 1.2
Ang II 1.2
ash 1.1
lectin 1.1
SARS 1.1
fused 1.1
mast cell 1.0
brain-derived neurotrophic factor 1.0
interleukin-2 1.0
tyrosine hydroxylase 1.0
bradykinin 1.0
oxytocin 1.0
endoplasmic reticulum 0.9
GABA 0.9
Met 0.8
cyclooxygenase 0.8
tyrosine kinase 0.8
inducible nitric oxide synthase 0.6
NAD 0.6
reserved 0.6
ACTH 0.6
glycoprotein 0.6
lipopolysaccharide 0.6
beta-endorphin 0.5
kit 0.5
MHC 0.5
PEG 0.5
ATP 0.5
ANOVA 0.4
CSF 0.4
cytochrome P450 0.3
CD4 0.3
TNF-alpha 0.2
glucagon 0.2
She 0.2
Sep 0.1
angiotensin II 0.1
growth hormone 0.0
interferon -0.0
fibronectin -0.1
catalase -0.6
superoxide dismutase -0.7
CD8 -0.7
SDS -0.7
insulin -0.8
JAMA -0.8
ATPase -1.0
albumin -1.0
lymphoid -1.0
NMR -1.3
Pseudomonas -1.3
Disease
bone cancer 14.9
osteolytic sarcoma 14.2
Giant cell sarcoma 13.9
connective tissue cancer 13.0
Dedifferentiated chordoma 12.3
Osteosarcoma 11.5
Osteosarcoma 11.5
Chondrosarcoma 10.5
Chondrosarcoma 10.5
bone marrow cancer 10.4
Pediatric Tumor 10.2
metastatic osteosarcoma 9.8
chondroblastic osteosarcoma 9.7
recurrent osteosarcoma 9.4
osteosarcoma 9.2
uterine corpus cancer 9.0
Bone marrow depression 8.8
silicotuberculosis 8.7
Ewing's sarcoma of bone 8.7
telangiectatic osteosarcoma 8.5
Pycnodysostosis 8.4
Ewing's sarcoma 8.3
HOS 8.1
bone neoplasm 8.1
chordoma 8.1
eye cancer 8.0
bone metastases 7.8
Postoperative infection 7.8
chondrosarcoma 7.8
hypercalcemia of malignancy 7.7
pericoronitis 7.6
Li-Fraumeni syndrome 7.5
Fibrosarcoma 7.5
Frey 7.5
Sarcoma 7.4
Sarcoma 7.4
public drinking 7.3
Malignant neoplasms 7.2
osteoblastic osteosarcoma 7.2
radiation carcinogenesis 6.9
ear infection 6.9
Cornelia de Lange syndrome 6.9
CNS cancer 6.8
second cancer 6.7
Giant cell tumor of bone 6.7
PTD 6.7
Desmoplastic small round cell tumor 6.6
hormone refractory prostate cancer 6.6
PBD 6.5
brain cancer 6.4
otitis externa 6.4
OSX 6.4
spindle cell sarcoma 6.4
chronic pain 6.4
enchondroma 6.3
skin hypersensitivity 6.2
childhood cancer 6.2
Lip 6.1
MPE 6.1
Giant cell tumor 6.0
fibrosarcoma 6.0
bone disease 6.0
metastatic pancreatic cancer 5.9
ADD 5.9
uterine cancer 5.9
neuroma 5.9
signet ring cell carcinoma 5.9
immune disorder 5.9
sarcoma 5.9
lymphosarcoma 5.8
pathological fracture 5.8
multicore 5.7
Bradley 5.7
PDB 5.6
pulpitis 5.6
asbestosis 5.6
Thyroid cancer 5.6
RAEB 5.5
lung metastases 5.5
renal cancer 5.4
acute nonlymphocytic leukemia 5.4
mastoiditis 5.4
cutaneous melanoma 5.4
residual cancer 5.3
RTS 5.3
osteopetrosis 5.3
familial cancer 5.3
embryonal rhabdomyosarcoma 5.2
physical dependence 5.2
retinoblastoma 5.2
rhabdomyosarcoma 5.1
ABS 5.1
diabetic neuropathy 5.1
silicosis 5.1
primary tumor 5.1
metastases 5.1
erysipelas 5.1
osteoporosis 5.0
thyroid cancer 5.0
ABS 5.0
Rhabdomyosarcoma 5.0
musculoskeletal disease 5.0
melanosis 5.0
periosteum 5.0
DMS 4.9
tumor growth 4.9
osteoma 4.9
regional pain syndrome 4.8
SPM 4.8
tumor initiation 4.7
osteochondroma 4.6
malignant fibrous histiocytoma 4.6
renal osteodystrophy 4.5
osteoporotic fracture 4.5
histiocytic lymphoma 4.4
liver cancer 4.4
Fox 4.4
carcinomatosis 4.4
renal cyst 4.4
Blocking 4.3
osteomalacia 4.3
primitive neuroectodermal tumor 4.3
chronic otitis media 4.3
otitis 4.2
liver cancer 4.2
craniopharyngioma 4.2
hyperostosis 4.2
Nasopharyngeal carcinoma 4.1
bronchogenic carcinoma 4.1
skin cancer 4.1
rare disease 4.1
sensory neuropathy 4.1
TCP 4.1
leukopenia 4.1
prostate cancer 4.1
AS1 4.0
solid tumor 4.0
tumor 4.0
epiphysis 4.0
metastatic breast cancer 4.0
brain abscess 3.9
tumor angiogenesis 3.9
carcinosarcoma 3.9
aggressiveness 3.9
synovial sarcoma 3.9
lung cancer 3.9
tumor progression 3.8
schizoaffective disorder 3.8
WRN 3.8
cancer 3.8
osteoarthritis 3.8
optic atrophy 3.8
THC 3.8
osteomyelitis 3.7
disinhibition 3.7
catalepsy 3.7
carcinoma 3.7
HTLV-I 3.7
hypopituitarism 3.6
Bladder 3.6
Bladder 3.6
Cushing's disease 3.6
NF2 3.6
CNS diseases 3.6
Bladder 3.6
hypercalcemia 3.6
HGF 3.6
peripheral neuropathy 3.5
leukemia 3.5
rectal cancer 3.5
residual disease 3.5
breast cancer 3.5
esophageal cancer 3.5
WT1 3.5
osteogenesis imperfecta 3.5
carcinoma of the breast 3.5
oral cancer 3.5
multiple myeloma 3.5
coxsackievirus 3.5
malignant mesothelioma 3.5
histoplasmosis 3.4
aplastic anemia 3.4
myelosuppression 3.4
esophageal cancer 3.4
spinal cord compression 3.4
BLM 3.3
periodontitis 3.3
cervical cancer 3.3
Pineal 3.2
neuropathy 3.2
plasmacytoma 3.2
tumorigenesis 3.2
otitis media 3.2
middle ear 3.2
non-Hodgkin's lymphoma 3.2
Turner syndrome 3.2
liposarcoma 3.1
Plaque 3.1
meninges 3.1
Larynx 3.1
Larynx 3.1
Larynx 3.1
diabetes insipidus 3.1
Larynx 3.0
pelvic inflammatory disease 3.0
Hodgkin's disease 3.0
endometrial cancer 3.0
obstructive jaundice 3.0
sickle cell disease 3.0
transitional cell carcinoma 3.0
myeloid leukemia 2.9
facial palsy 2.9
Fanconi 2.9
rheumatoid arthritis 2.9
bladder cancer 2.9
pancreatic cancer 2.9
hematologic malignancies 2.9
B-cell lymphoma 2.9
scrotum 2.9
cystitis 2.9
PML 2.9
periodontal disease 2.8
disseminated intravascular coagulation 2.8
hepatic encephalopathy 2.8
melanoma 2.8
benign tumor 2.8
gastric cancer 2.8
Prostate Cancer 2.8
lipoma 2.7
neuroblastoma 2.7
pulmonary tuberculosis 2.7
chronic lymphocytic leukemia 2.7
HCG 2.7
primary hyperparathyroidism 2.6
thrombocytopenia 2.6
CCD 2.6
pancytopenia 2.6
SCH 2.6
dysphagia 2.6
leiomyoma 2.6
vagina 2.5
chronic lymphocytic leukemia 2.5
SCID 2.5
CAM 2.5
herpes simplex 2.5
colon cancer 2.4
neutropenia 2.4
CTX 2.3
iron overload 2.3
ATM 2.2
ankylosing spondylitis 2.2
NAME 2.2
NOD 2.2
incontinence 2.2
arthritis 2.2
suicide 2.1
ovarian cancer 2.1
acute myeloid leukemia 2.1
pulmonary fibrosis 2.1
MCF 2.1
chronic pancreatitis 2.1
carcinogenesis 2.1
anemia 2.0
myelodysplastic syndrome 2.0
SAR 2.0
bacterial infection 2.0
Melanoma 2.0
head and neck cancer 1.9
arthropathy 1.9
scoliosis 1.8
Still 1.8
colorectal cancer 1.8
chronic myeloid leukemia 1.7
SEM 1.7
DBA 1.6
APC 1.6
TEM 1.6
hyperthyroidism 1.6
adenoma 1.5
confusion 1.5
dysplasia 1.5
TEM 1.5
squamous cell carcinoma 1.5
respiratory disease 1.5
chronic renal failure 1.4
emphysema 1.4
cold 1.4
myopathy 1.4
lung carcinoma 1.4
lymphoma 1.3
Poland 1.2
celiac disease 1.2
dermatitis 1.2
cirrhosis 1.1
parkinsonism 1.1
aggression 1.1
pheochromocytoma 1.1
respiratory failure 1.0
Leukemia 1.0
hepatitis 1.0
ash 1.0
fits 1.0
pancreatitis 0.9
lung disease 0.9
uterus 0.9
migraine 0.9
cerebral ischemia 0.9
Best 0.8
mole 0.8
chronic disease 0.7
glioblastoma 0.7
encephalitis 0.7
amyotrophic lateral sclerosis 0.7
SARS 0.7
cardiomyopathy 0.6
mole 0.5
acute lymphoblastic leukemia 0.5
renal cell carcinoma 0.5
non-small cell lung cancer 0.4
tuberculosis 0.3
addiction 0.1
dementia 0.1
glioma -0.0
renal failure -0.1
autism -0.1
cardiovascular disease -0.1
adenocarcinoma -0.2
hepatocellular carcinoma -0.2
Infection -0.3
multiple sclerosis -0.5
SDS -0.7
sepsis -0.8
Alzheimer's disease -0.8
type 2 diabetes -0.9
sepsis -1.0
schizophrenia -1.0
myocardial infarction -1.1
immunodeficiency -1.2
heart failure -1.2
atherosclerosis -1.3
infectious diseases -1.4
asthma -1.5
depression -1.5
AIDS -2.0
obesity -2.0
diabetes -2.2
hypertension -2.5
Symptom
Metastatic bone pain 12.6
Other pain 10.2
cancer pain 9.7
bone pain 9.2
skin pain 8.7
prominent nose 8.5
No pain 8.1
breakthrough pain 7.8
Severe pain 7.6
Flare 7.4
physical symptom 7.0
otalgia 5.9
pain 5.4
analgesia 5.3
dry skin 4.9
dental pain 4.7
Neuropathic pain 4.4
torticollis 4.2
neuralgia 4.1
chronic cough 3.9
myalgia 3.2
low back pain 3.2
arthralgia 3.1
acute pain 3.0
constipation 2.6
discomfort 2.5
paresis 2.4
back pain 2.3
discomfort 2.3
anorexia 2.2
nausea and vomiting 1.7
insomnia 1.5
headache 1.5
nausea 1.4
agitation 1.3
chest pain 0.8
fatigue 0.2
collapse 0.1
anesthesia -0.8
Drug
Rubitecan 11.9
Iguratimod 10.3
Lumiracoxib 9.3
Barium sulfate 9.1
Cilengitide 8.7
Propentofylline 8.6
EHDP 8.3
Celebrex 8.0
Zoledronic acid 7.5
Zoledronic acid 7.3
Anakinra 6.9
RAL 6.9
Denosumab 6.8
Exenatide 6.6
Teriparatide 6.5
Epigallocatechin 6.1
Cetuximab 6.0
GEO 5.9
PDL 5.5
Gelatin 5.1
APD 5.1
NVP 5.0
TAK 5.0
ETS 4.5
Honey 4.5
IL-1ra 4.5
Simvastatin 4.2
TTC 4.0
Capsicum 3.8
Silica 3.7
Imatinib 3.6
G-CSF 3.5
ADM 3.3
p75 3.0
Adriamycin 2.7
citric acid 2.6
FAD 2.5
CTX 2.4
CTX 2.4
CAM 2.4
PTH 2.2
Monit 2.1
ROC 2.0
ROS 1.7
CTX 1.6
CSF 1.6
lysine 1.4
ZnO 1.2
Gel 1.0
Cardiovasc -2.7
Enzyme
DSR 8.0
KLK7 7.4
phosphatidylinositol-4,5-bisphosphate 3-kinase 7.3
methylthioadenosine phosphorylase 7.1
cytosine deaminase 6.9
nicotinamide phosphoribosyltransferase 6.4
carboxypeptidase E 6.3
serine hydroxymethyltransferase 5.7
sphingosine kinase 5.4
caspase-7 5.1
caspase-7 5.1
GRK5 4.8
lysyl oxidase 4.6
MDP 4.5
polo-like kinase 1 4.3
caspase-8 4.2
prostate-specific membrane antigen 4.1
PARP 4.0
CaMKII 3.9
MMP 3.9
PDK1 3.8
caspase-3 3.7
caspase-9 3.6
PKG 3.6
kinesin 3.6
luciferase 3.5
phosphoinositide 3-kinase 3.4
MEK 3.3
mitogen-activated protein kinase 3.2
ERK 3.1
thymidylate synthase 3.1
NOS 3.1
phosphatidylinositol 3-kinase 3.1
alkaline phosphatase 2.9
protein kinase C 2.9
protein kinase 2.8
deaminase 2.6
kallikrein 2.3
AMPK 2.3
AMP-activated protein kinase 2.2
P-glycoprotein 2.2
GSK 2.2
prostate-specific antigen 2.1
proteasome 2.1
thymidine kinase 2.0
ACS 1.8
topoisomerase 1.7
topoisomerase 1.6
focal adhesion kinase 1.5
AMPK 1.3
acid phosphatase 1.3
tyrosine hydroxylase 1.1
NO synthase 1.0
APC 0.9
collagenase 0.7
phosphodiesterase 0.7
lactate dehydrogenase 0.1
reverse transcriptase -0.0
RNA polymerase -0.2
trypsin -0.5
catalase -0.9
superoxide dismutase -0.9
ATPase -1.1
Compound
[1,2,4]triazolo[4,3-a]pyrimidine 12.6
Gelsemine 11.9
Tomatidine 10.3
Tomatidine 10.3
Lappaconitine 10.2
Dezocine 10.1
Tetrahydropalmatine 9.6
N-Hydroxysuccinimide 9.3
Radon-222 9.2
Alantolactone 9.1
PTSM 9.0
1,3-dihydro-2H-benzimidazol-2-one 8.9
Lycorine 8.8
Bufalin 8.6
EHDP 8.5
Resiniferatoxin 8.5
Oxycodone 8.5
CHNO 8.5
CHNO 8.4
Tricalcium phosphate 8.2
Cyanate 7.9
benzo[c]phenanthridine 7.9
NCD 7.8
Naringin 7.7
Paeonol 7.5
1,2-ethanediamine 7.5
Risedronate 7.4
Daunomycin 7.4
1,2-ethanediamine 7.4
Clofazimine 7.2
Wogonin 7.2
MNNG 7.0
Naringin 7.0
Allyl isothiocyanate 7.0
MPE 6.9
2,4-dichlorophenyl 6.7
2,4-dichlorophenyl 6.7
Loperamide 6.7
Etanercept 6.6
PBD 6.5
Pimozide 6.5
Ursolic acid 6.3
propionamide 6.3
Topotecan 6.3
propionamide 6.3
APT 6.2
MK801 6.2
Morin 6.2
iodobenzene 6.1
Iodo 6.1
APTES 6.1
Triptolide 5.9
Daunorubicin 5.9
Tanshinone 5.9
Sphingosine 1-phosphate 5.9
Alendronate 5.8
Topotecan 5.7
Alendronate 5.7
5-Aza-2'-deoxycytidine 5.7
pentosidine 5.6
Morphine 5.6
CaO 5.5
Dithiothreitol 5.5
Tramadol 5.5
DHPG 5.5
Brilliant Blue 5.5
DAMGO 5.5
Lip 5.5
HAP 5.4
Spironolactone 5.4
Epigallocatechin 5.3
IBA 5.3
ADR 5.3
Dithiothreitol 5.3
1H-imidazole 5.2
BAP 5.2
4-methylphenyl 5.1
strontium 5.1
IBA 5.1
tetraethyl orthosilicate 5.1
Adriamycin 5.0
Glutaraldehyde 5.0
Bismuth 5.0
Minocycline 5.0
Neurotensin 5.0
1H-pyrazole 4.9
PID 4.9
PPI 4.9
Diclofenac 4.9
PID 4.9
Epigallocatechin gallate 4.9
Curcumin 4.8
4-AP 4.8
Sialic acid 4.8
5-methylisoxazole 4.8
Alizarin 4.8
Hoechst 33342 4.7
1H-pyrazole 4.7
Berberine 4.6
AEA 4.6
APAP 4.5
Titanium dioxide 4.5
Thymidine 4.5
DTPA 4.5
isoquinoline 4.4
Resveratrol 4.4
Cyt 4.4
TMA 4.3
Amide 4.3
Catechol 4.3
1H-indole 4.3
DMS 4.3
Gemcitabine 4.2
CCP 4.2
Gemcitabine 4.2
1H-imidazole 4.1
Cbl 4.1
TCP 4.1
TCP 4.1
Naloxone 4.0
MTT 4.0
TCP 4.0
TCP 4.0
boric acid 4.0
MSM 4.0
ATF 4.0
SPM 4.0
DTT 3.9
CPA 3.9
selenium 3.9
Wellcome 3.9
DTT 3.9
MEK 3.8
CPP 3.8
SET 3.8
rubidium 3.8
Chitosan 3.8
CPP 3.8
2-hydroxyethyl 3.8
2-hydroxyethyl 3.8
2-hydroxyethyl 3.8
2-hydroxyethyl 3.8
2-hydroxyethyl 3.8
2-hydroxyethyl 3.8
2-hydroxyethyl 3.8
vanadium 3.7
Cycloheximide 3.7
Vancomycin 3.7
chalcone 3.6
dUTP 3.6
isoxazole 3.6
Hematoxylin 3.6
aspartic acid 3.6
aspartic acid 3.5
Neu5Ac 3.5
Capsaicin 3.5
benzophenone 3.5
Phosphatidylinositol 3.5
2-hydroxyethyl 3.4
Oxytocin 3.4
aspartic acid 3.4
TNF 3.4
ADP-ribose 3.4
CTP 3.3
benzamide 3.3
propionic acid 3.3
propionic acid 3.3
aspartic acid 3.3
Substance P 3.3
Trypsin 3.2
Melatonin 3.2
Neo 3.2
titanium 3.2
Metformin 3.2
Rapamycin 3.2
Lactate 3.2
Metformin 3.2
Tamoxifen 3.1
5-FU 3.1
Pluronic 3.1
Tamoxifen 3.1
DDP 3.0
Abbott 3.0
Triton 2.9
ALP 2.9
PEI 2.9
PEI 2.8
kaempferol 2.8
Panam 2.7
Histone 2.7
ASA 2.6
N-acetylcysteine 2.5
DMSO 2.5
pyrrolidine 2.5
cyclohexane 2.5
FAD 2.5
pyrrolidine 2.4
tin 2.4
Glutamate 2.3
Vitamin D 2.2
Ang II 2.2
vitamin D 2.1
acridine 2.1
silver 2.0
A 3 2.0
Primatol 2.0
Primatol 2.0
PMA 2.0
NMDA 1.9
TNM 1.9
MDA 1.9
glutamate 1.9
adenosylmethionine 1.9
ACS 1.8
ACS 1.8
Asp 1.8
Primatol 1.8
Tris 1.8
DPPH 1.8
cAMP 1.7
AMPA 1.7
formaldehyde 1.6
CTX 1.6
Tris 1.6
CAM 1.6
bromide 1.5
threonine 1.5
phosphate 1.5
Pac 1.5
Neuronal 1.4
iron 1.4
NH2 1.4
acetic acid 1.4
TEM 1.4
calcium 1.4
retinoic acid 1.3
PMA 1.3
NAD 1.2
PGE2 1.1
GTP 1.1
methionine 1.1
oxygen 1.1
carbonate 1.1
formaldehyde 0.9
lysine 0.9
iodine 0.9
GABA 0.8
fluorine 0.8
nitrate 0.8
GABA 0.8
boron 0.7
vinyl 0.7
potassium 0.7
ACTH 0.6
nitrogen 0.6
NAD 0.6
cGMP 0.5
serine 0.5
ATP 0.5
zinc 0.5
alanine 0.4
DNA 0.3
glutamine 0.2
methane 0.2
Insulin 0.1
PEG 0.1
aluminum 0.1
Mg2+ 0.1
salt 0.1
Dec 0.1
nickel -0.0
5-HT -0.0
proline -0.1
tyrosine -0.1
acetonitrile -0.1
noradrenaline -0.1
Gly -0.2
cysteine -0.3
water -0.3
PEG -0.3
His -0.4
sodium -0.4
Clin -0.4
hydrogen -0.4
silicon -0.5
phosphorus -0.6
copper -0.6
arginine -0.6
Phe -0.7
SDS -0.8
sulfate -0.9
glucose -1.0
leucine -1.0
ammonium -1.1
nitric oxide -1.7
acetate -1.9
ethanol -2.2
BMC -2.6