Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts: Gene/Protein Disease Symptom Drug Enzyme Compound   Target Concepts: Gene/Protein Disease Symptom Drug Enzyme Compound

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Query: UMLS:C0278883 (metastatic melanoma)
6,224 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .

Human Gene/Protein BRAF 917 Sep 335 MEK 324 interleukin-2 287 PD-1 259 Mol 251 CTLA-4 208 CD8 201 cytokine 192 interferon 181 IL-2 166 PD-L1 139 tyrosinase 127 CD4 120 IFN 116 HLA 115 MAPK 115 NRAS 107 gp100 107 p53 104 nodal 103 lymphocyte antigen 99 MART-1 94 ERK 80 lactate dehydrogenase 79 AKT 79 F10 75 PI3K 71 Melan-A 69 RAF 67 HLA-A2 65 PD1 64 vascular endothelial growth factor 61 She 60 CTLA4 60 interferon-alpha 59 S100 57 KIT 56 interleukin 2 55 collagen 51 tumor necrosis factor 51 lymphokine 50 FDG 50 IFN-gamma 48 MRI 47 Bcl-2 47 tyrosine kinase 45 IL-6 44 TNF 44 lymphoid 44 fibronectin 42 MHC 42 GM-CSF 41 glycoprotein 41 PTEN 41 matrix metalloproteinase 40 HLA-DR 39 MHC class I 38 MEL 36 p21 36 E-cadherin 35 interferon alpha 35 mTOR 35 c-kit 34 TCR 34 melanoma antigen 34 caspase-3 33 MITF 33 major histocompatibility complex 33 interferon-gamma 31 T cell receptor 31 IL-10 31 ERK1 30 VEGF 30 extracellular signal-regulated kinase 30 microphthalmia-associated transcription factor 30 catenin 30 cytotoxic T-lymphocyte antigen 4 30 IL-8 30 granulocyte-macrophage colony-stimulating factor 29 more...

Disease metastatic melanoma 6224 melanoma 4450 cancer 2595 tumor 2463 metastases 1235 Melanoma 912 cutaneous melanoma 261 skin cancer 260 mole 250 tumor growth 241 tumor progression 222 brain metastases 171 carcinoma 133 renal cell carcinoma 130 stage IV melanoma 121 primary tumor 119 tumorigenesis 95 breast cancer 85 mole 84 colitis 79 lung cancer 79 benign nevi 76 rash 69 sarcoma 65 lung metastases 64 non-small cell lung cancer 63 vitiligo 60 adenocarcinoma 59 dysplastic nevi 57 squamous cell carcinoma 56 lymphoma 51 thrombocytopenia 47 uveal melanoma 46 leukemia 43 metastatic renal cell carcinoma 42 hepatitis 41 neutropenia 38 stage III melanoma 38 solid tumor 37 liver metastases 35 colorectal cancer 35 melanosis 34 dermatitis 33 aggressiveness 32 prostate cancer 31 carcinogenesis 31 glioma 31 myelosuppression 30 hepatocellular carcinoma 29 renal cancer 29 mimicry 29 pruritus 27 lung carcinoma 27 lymphadenopathy 26 melanoma in situ 26 multiple myeloma 25 ovarian cancer 24 pneumonia 24 photosensitivity 23 Hodgkin's disease 23 ocular melanoma 23 intussusception 22 anemia 22 influenza 21 plaque 21 uveitis 20 hypothyroidism 19 recurrent melanoma 19 colon cancer 19 aggression 19 herpes simplex 18 sarcoidosis 18 neuropathy 18 HIV 18 basal cell carcinoma 18 neuroblastoma 18 fibrosarcoma 18 blue nevus 18 bowel obstruction 17 cancer regression 16 more...

Symptom fatigue 85 diarrhea 78 nausea 60 vomiting 41 pain 38 abdominal pain 35 chills 25 nausea and vomiting 24 arthralgia 21 headache 20 dyspnea 19 anorexia 18 erythema 18 exhaustion 17 weakness 15 myalgia 14 constipation 11 Ill 9 seizures 9 cough 8 discomfort 8 discomfort 8 asthenia 7 back pain 7 collapse 6 anesthesia 6 exertional dyspnea 5 lethargy 5 acute abdomen 5 cachexia 5 rigors 5 blurred vision 4 starvation 4 syncope 4 paresthesia 4 acidity 4 bone pain 4 hepatomegaly 4 shortness of breath 4 hemoptysis 4 oliguria 4 dizziness 3 pelvic pain 3 respiratory distress 3 tinnitus 3 vertigo 3 decreased appetite 3 clubbing 2 ophthalmoplegia 2 sleepiness 2 intestinal bleeding 2 tonic-clonic seizure 2 night sweats 2 non-productive cough 2 epigastric pain 2 ataxia 2 colic 2 dry skin 2 eye pain 2 orthopnea 2 chest pain 2 low back pain 2 agitation 2 photophobia 2 paresis 2 loss of taste 1 stridor 1 angina 1 right upper quadrant pain 1 tingling 1 analgesia 1 productive cough 1 testicular pain 1 flushing 1 HSA 1 dental pain 1 polyuria 1 tremor 1 numbness 1 acute abdominal pain 1 more...

Drug Dermatol 372 IL-2 170 Ipilimumab 164 CSF 48 IFN-gamma 47 p75 12 MAP 12 ROS 11 Fotemustine 10 BLM 9 lysine 8 Taxol 8 CAM 7 PDL 7 Sorafenib 7 Imatinib 6 Proleukin 5 Temodal 5 Imiquimod 5 Bevacizumab 5 IFN-beta 5 Monit 4 Cardiovasc 4 Dasatinib 4 Lenalidomide 4 Bortezomib 4 CCL 3 GEO 3 Intron A 3 Fragment 3 Spectrum 3 ADM 3 Adriamycin 3 Activin 3 ABC 3 Glutathione 3 Infliximab 3 Gastro 3 Intron A 3 Infliximab 3 Leaf 3 Histamine 3 Spectrum 3 ascorbate 3 VCR 3 ETS 3 CTC 2 Taxotere 2 Gleevec 2 Provenge 2 ACT 2 Gel 2 Albumin 2 NVP 2 TFT 2 NADH 2 uPA 2 Canvaxin 2 CDX 2 Alliance 2 Genasense 2 VCR 2 CTX 2 Fluorescein 2 Docetaxel 2 CDX 2 L-tyrosine 2 CTC 2 Gefitinib 2 balanced salt solution 2 Adenosine triphosphate 2 Bifidobacterium 2 Plavix 1 FAD 1 Deferasirox 1 Gelatin 1 Zoladex 1 PCB 1 Bexxar 1 Vitamin B 1 more...

Enzyme MEK 349 mitogen-activated protein kinase 264 ERK 202 tyrosinase 122 lactate dehydrogenase 84 protein kinase 53 focal adhesion kinase 51 protein kinase C 28 reverse transcriptase 27 caspase-3 26 proteasome 19 DCF 19 luciferase 17 P-glycoprotein 14 caspase-9 12 PARP 12 collagenase 11 MAP 10 granzyme B 10 phosphatidylinositol 3-kinase 9 thrombin 9 RNA polymerase 9 urokinase-type plasminogen activator 9 cathepsin B 8 lipase 8 MEKK1 7 aspartate aminotransferase 7 transcriptase 7 matrix metalloproteinase 2 7 alanine aminotransferase 7 alkaline phosphatase 6 NO synthase 6 MMP 6 peroxidase 6 ACS 6 AMP-activated protein kinase 5 ATPase 5 calcineurin 5 caspase-1 5 NADPH oxidase 5 catalase 5 NADPH oxidase 5 cdc2 5 phosphodiesterase 5 arginase 5 phosphoinositide 3-kinase 4 thyroid peroxidase 4 GSK 4 tissue plasminogen activator 4 adenylate cyclase 4 caspase-8 4 APC 4 guanylate cyclase 4 plasmin 4 ribonucleotide reductase 4 ribonucleotide reductase 4 matrix metalloproteinase 9 4 glutathione reductase 4 transglutaminase 4 thioredoxin reductase 4 IKK 4 AMPK 4 phospholipase C 4 AMPK 3 hexokinase 3 glutathione S-transferase 3 RGP 3 enolase 3 CD10 3 cathepsin D 3 trypsin 3 AST 3 methionine adenosyltransferase 2 thymidine kinase 2 thromboplastin 2 DNA methyltransferase 2 chloramphenicol acetyltransferase 2 ubiquitin-protein ligase 2 chymotrypsin 2 demethylase 2 more...

Compound Clin 501 Dec 450 MEK 324 DNA 304 DIC 122 oxygen 64 tyrosine 54 TNF 44 Interleukin-2 38 Temozolomide 33 serine 30 ATP 28 sulfate 28 calcium 28 BCNU 27 GD3 26 His 26 MTT 25 arginine 25 PEG 24 acetate 24 glucose 24 methionine 23 retinoic acid 23 lysine 19 iodine 17 DDP 17 nitric oxide 17 threonine 16 galactose 16 water 16 boron 16 leucine 16 glutamate 15 BCG 15 creatinine 15 PEG 15 Phe 14 sodium 14 phosphate 13 hydrogen 13 Asp 13 cAMP 13 valine 12 Melanin 12 cysteine 12 fluorine 11 zinc 11 nitrogen 11 BLM 10 iron 10 MAP 10 cobalt 10 Gly 10 copper 10 Optimal 9 MIA 8 GSH 8 MDA 8 acetic acid 8 GSH 8 bromide 8 ethanol 8 CAM 8 alanine 8 glutamine 8 GM3 7 ASA 7 Pac 7 Cardiol 7 neopterin 7 SDS 7 vitamin D 7 ATF 7 TAP 6 AMP 6 CO2 6 tryptophan 6 GM2 6 Tamoxifen 6 more...

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