Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0278883 (metastatic melanoma)
6,224 document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
C21orf34 12.3
Mdm4 p53 binding protein homolog 12.3
hypothetical protein FLJ11151 12.3
SSX4 protein 12.3
SSX4B 12.3
TCRAV2S1 11.7
C7orf4 11.3
REG1A protein 11.3
ZNF490 11.3
P2RY10 11.3
LOC642587 11.3
transmembrane protein 31 11.3
SCD5 protein 11.3
NRAS1 11.0
ZSWIM7 10.7
FAM41C 10.7
RIP5 10.7
LINGO3 10.7
GON4L 10.7
Flotillin 2 10.7
ovostatin 2 10.7
small nuclear ribonucleoprotein polypeptide A 10.7
KRTCAP3 10.3
GPNMB protein 10.3
renal cell carcinoma 4 10.3
hPARP-3 10.3
MIA protein 10.3
EYA1 protein 10.0
THBS1 protein 10.0
MAGE2 10.0
KDELR3 10.0
AP-2B 10.0
developmentally regulated GTP-binding protein 2 10.0
cytotoxic T-lymphocyte protein 4 10.0
microphtalmia-associated transcription factor 9.9
TM9SF4 9.9
MAGE3 9.8
ATP-binding cassette sub-family B member 5 9.7
APO B-100 9.7
EVPL 9.7
more...
Disease
Craniopharyngeal duct 12.3
Craniopharyngeal duct 12.3
Craniopharyngeal duct 12.3
metastatic melanoma 12.3
Cervical melanoma 11.3
Metastatic malignant melanoma 10.8
Polyradiculoneuritis 10.7
pediatric oligodendroglioma 10.7
stage IV melanoma 10.6
malignant nevus 10.3
stage III melanoma 10.2
Melanoma-associated retinopathy 10.1
Dorsal midbrain syndrome 10.0
benign nevi 9.7
Tumor ulceration 9.5
Lumbosacral radiculopathy 9.5
recurrent melanoma 9.5
Neutrophilic panniculitis 9.4
Clear cell sarcoma of tendons and aponeuroses 9.3
Melanoma 9.2
cancer regression 9.2
Acquired generalized lipodystrophy 9.2
Desmoplastic malignant melanoma 9.0
Pituitary macroadenoma 9.0
Autoimmune hypophysitis 8.9
stage I melanoma 8.8
Derailment 8.7
superficial spreading malignant melanoma 8.7
melanoma in situ 8.6
melanoma stage 8.5
CIIP 8.5
Mixed tumor 8.5
dysplastic nevi 8.5
cutaneous melanoma 8.5
Autoimmune myocarditis 8.4
melanoma 8.4
halo nevus 8.3
Malignant blue nevus 8.3
ocular melanoma 8.2
Hypophysitis 8.2
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Symptom
Local swelling 8.6
Cullen's sign 7.9
Murphy's sign 6.4
brittle nails 6.3
non-productive cough 5.2
generalized rash 5.2
rigors 5.0
chills 4.9
jaw pain 4.8
eye pain 4.8
orthopnea 4.5
arthralgia 3.9
testicular pain 3.9
loss of taste 3.8
asthenia 3.8
decreased appetite 3.7
nausea 3.7
nausea and vomiting 3.7
intestinal bleeding 3.7
clubbing 3.5
oliguria 3.5
myalgia 3.4
syncopal episodes 3.3
dry skin 3.3
blurred vision 3.3
abdominal cramps 3.3
adenitis 3.2
night sweats 3.1
fatigue 3.1
acute abdomen 3.1
tonic-clonic seizure 3.0
leg edema 2.9
exertional dyspnea 2.9
right upper quadrant pain 2.9
erythema 2.8
diarrhea 2.8
chronic back pain 2.8
anorexia 2.7
vomiting 2.7
bone pain 2.7
more...
Drug
Ecromeximab 12.3
Ipilimumab 11.0
Vaccinia immune globulin 10.7
Canvaxin 10.2
Zeniplatin 10.0
Fotemustine 9.6
Proleukin 9.6
Temodal 9.1
Carbetimer 9.0
Peginterferon alfa-2b 7.8
Peginterferon alfa-2b 7.8
Sodium dichloroacetate 7.7
Provenge 7.5
Genasense 7.5
Bleomycins 7.2
Lonafarnib 7.1
Intron A 6.9
Leukine 6.9
Intron A 6.8
Paraplatin 6.8
Cerezyme 6.5
Midostaurin 6.3
Bexxar 6.2
Cilengitide 6.2
Ceredase 6.1
Velban 6.1
Omniscan 5.9
Thymopentin 5.9
Tirapazamine 5.9
PDL 5.8
Ferumoxytol 5.7
Cerezyme 5.6
Imiquimod 5.6
Nexavar 5.6
Ethyol 5.5
Intron A 5.5
Vindesine 5.5
Vindesine 5.4
Plavix 5.4
TFT 5.3
more...
Enzyme
N-acetylneuraminylgalactosylglucosylceramide 8.4
prolyl 3-hydroxylase 7.7
MEK 6.6
nicotinic acid phosphoribosyltransferase 6.1
tyrosinase 6.1
RGP 6.1
EC 4.4.1.5 6.1
adamalysin 6.0
cancer procoagulant 5.8
N-acetylglucosaminyltransferase III 5.7
coagulation factor VIIa 5.7
quinolinic acid phosphoribosyltransferase 5.6
DCF 5.6
calpain 3 5.1
N-acetylglucosaminyltransferase V 5.0
neuropsin 5.0
methioninase 5.0
methionine synthase reductase 4.7
calpain 3 4.6
methylthioadenosine phosphorylase 4.5
oxytocinase 4.5
sphingomyelin synthase 4.4
eEF2 kinase 4.4
spermidine/spermine N1-acetyltransferase 4.4
MEKK1 4.3
estrogen sulfotransferase 4.2
hyaluronate lyase 4.0
granzyme B 4.0
matrix metalloproteinase 2 4.0
PNL 3.9
methionine adenosyltransferase 3.9
argininosuccinate synthetase 3.9
lactate dehydrogenase 3.9
caspase-4 3.8
mitogen-activated protein kinase 3.8
cathepsin H 3.8
nicotinamide phosphoribosyltransferase 3.8
ubiquitin-protein ligase 3.7
caspase-4 3.6
galactocerebrosidase 3.6
more...
Compound
4-acetylbenzoic acid 9.5
2-acetylbenzoic acid 9.5
HBPA 9.2
Cirsiliol 9.0
8-aminooctanoic acid 8.9
4-Methylcatechol 8.5
Diphenylcyclopropenone 8.4
Chlorozotocin 8.2
3-phenylpropanamide 8.2
M1A 8.0
DIBA 7.9
DIC 7.9
aminomalonic acid 7.9
Temozolomide 7.7
Hinokitiol 7.4
2-AA 7.1
Bixin 7.1
Bixin 7.1
Interleukin-2 7.1
MEK 7.0
Neu5,9Ac2 6.9
CI-921 6.9
Tomatine 6.9
PCNU 6.8
Flavone acetic acid 6.6
Thiostrepton 6.5
GD3 6.5
EGT 6.4
Velban 6.4
NOXA 6.4
BIF 6.0
Deguelin 6.0
BCNU 5.9
Deoxyguanosine 5.9
Melanin 5.8
PGE3 5.8
Estramustine 5.8
Parthenolide 5.7
Diallyl disulfide 5.6
Diallyl disulfide 5.6
more...