Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts: Gene/Protein Disease Symptom Drug Enzyme Compound   Target Concepts: Gene/Protein Disease Symptom Drug Enzyme Compound

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Query: UMLS:C0278883 (metastatic melanoma)
6,224 document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .

Human Gene/Protein BRAF 917 Sep 335 MEK 324 interleukin-2 287 PD-1 259 Mol 251 CTLA-4 208 CD8 201 cytokine 192 interferon 181 IL-2 166 PD-L1 139 tyrosinase 127 CD4 120 IFN 116 HLA 115 MAPK 115 gp100 107 NRAS 107 p53 104 nodal 103 lymphocyte antigen 99 MART-1 94 ERK 80 AKT 79 lactate dehydrogenase 79 F10 75 PI3K 71 Melan-A 69 RAF 67 HLA-A2 65 PD1 64 vascular endothelial growth factor 61 She 60 CTLA4 60 interferon-alpha 59 S100 57 KIT 56 interleukin 2 55 tumor necrosis factor 51 more...

Disease metastatic melanoma 6224 melanoma 4450 cancer 2595 tumor 2463 metastases 1235 Melanoma 912 cutaneous melanoma 261 skin cancer 260 mole 250 tumor growth 241 tumor progression 222 brain metastases 171 carcinoma 133 renal cell carcinoma 130 stage IV melanoma 121 primary tumor 119 tumorigenesis 95 breast cancer 85 mole 84 colitis 79 lung cancer 79 benign nevi 76 rash 69 sarcoma 65 lung metastases 64 non-small cell lung cancer 63 vitiligo 60 adenocarcinoma 59 dysplastic nevi 57 squamous cell carcinoma 56 lymphoma 51 thrombocytopenia 47 uveal melanoma 46 leukemia 43 metastatic renal cell carcinoma 42 hepatitis 41 neutropenia 38 stage III melanoma 38 solid tumor 37 liver metastases 35 more...

Symptom fatigue 85 diarrhea 78 nausea 60 vomiting 41 pain 38 abdominal pain 35 chills 25 nausea and vomiting 24 arthralgia 21 headache 20 dyspnea 19 anorexia 18 erythema 18 exhaustion 17 weakness 15 myalgia 14 constipation 11 Ill 9 seizures 9 discomfort 8 discomfort 8 cough 8 asthenia 7 back pain 7 collapse 6 anesthesia 6 exertional dyspnea 5 cachexia 5 acute abdomen 5 lethargy 5 rigors 5 blurred vision 4 paresthesia 4 hepatomegaly 4 starvation 4 hemoptysis 4 syncope 4 acidity 4 bone pain 4 shortness of breath 4 more...

Drug Dermatol 372 IL-2 170 Ipilimumab 164 CSF 48 IFN-gamma 47 MAP 12 p75 12 ROS 11 Fotemustine 10 BLM 9 Taxol 8 lysine 8 PDL 7 CAM 7 Sorafenib 7 Imatinib 6 Proleukin 5 Temodal 5 Bevacizumab 5 Imiquimod 5 IFN-beta 5 Lenalidomide 4 Monit 4 Bortezomib 4 Cardiovasc 4 Dasatinib 4 GEO 3 Histamine 3 ETS 3 Spectrum 3 VCR 3 ADM 3 Spectrum 3 CCL 3 Infliximab 3 ascorbate 3 Adriamycin 3 Glutathione 3 Infliximab 3 Intron A 3 more...

Enzyme MEK 349 mitogen-activated protein kinase 264 ERK 202 tyrosinase 122 lactate dehydrogenase 84 protein kinase 53 focal adhesion kinase 51 protein kinase C 28 reverse transcriptase 27 caspase-3 26 DCF 19 proteasome 19 luciferase 17 P-glycoprotein 14 caspase-9 12 PARP 12 collagenase 11 MAP 10 granzyme B 10 phosphatidylinositol 3-kinase 9 RNA polymerase 9 thrombin 9 urokinase-type plasminogen activator 9 cathepsin B 8 lipase 8 MEKK1 7 aspartate aminotransferase 7 alanine aminotransferase 7 matrix metalloproteinase 2 7 transcriptase 7 NO synthase 6 MMP 6 ACS 6 peroxidase 6 alkaline phosphatase 6 NADPH oxidase 5 ATPase 5 AMP-activated protein kinase 5 NADPH oxidase 5 caspase-1 5 more...

Compound Clin 501 Dec 450 MEK 324 DNA 304 DIC 122 oxygen 64 tyrosine 54 TNF 44 Interleukin-2 38 Temozolomide 33 serine 30 calcium 28 ATP 28 sulfate 28 BCNU 27 GD3 26 His 26 MTT 25 arginine 25 glucose 24 PEG 24 acetate 24 methionine 23 retinoic acid 23 lysine 19 nitric oxide 17 DDP 17 iodine 17 leucine 16 galactose 16 boron 16 water 16 threonine 16 creatinine 15 glutamate 15 PEG 15 BCG 15 Phe 14 sodium 14 hydrogen 13 more...

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