Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0278883 (metastatic melanoma)
 6,224 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
BRAF 917
Sep 335
MEK 324
interleukin-2 287
PD-1 259
Mol 251
CTLA-4 208
CD8 201
cytokine 192
interferon 181
IL-2 166
PD-L1 139
tyrosinase 127
CD4 120
IFN 116
MAPK 115
HLA 115
NRAS 107
gp100 107
p53 104
more...
Disease
metastatic melanoma 6224
melanoma 4450
cancer 2595
tumor 2463
metastases 1235
Melanoma 912
cutaneous melanoma 261
skin cancer 260
mole 250
tumor growth 241
tumor progression 222
brain metastases 171
carcinoma 133
renal cell carcinoma 130
stage IV melanoma 121
primary tumor 119
tumorigenesis 95
breast cancer 85
mole 84
colitis 79
more...
Symptom
fatigue 85
diarrhea 78
nausea 60
vomiting 41
pain 38
abdominal pain 35
chills 25
nausea and vomiting 24
arthralgia 21
headache 20
dyspnea 19
anorexia 18
erythema 18
exhaustion 17
weakness 15
myalgia 14
constipation 11
Ill 9
seizures 9
cough 8
more...
Drug
Dermatol 372
IL-2 170
Ipilimumab 164
CSF 48
IFN-gamma 47
p75 12
MAP 12
ROS 11
Fotemustine 10
BLM 9
Taxol 8
lysine 8
CAM 7
Sorafenib 7
PDL 7
Imatinib 6
Proleukin 5
Imiquimod 5
Temodal 5
Bevacizumab 5
more...
Enzyme
MEK 349
mitogen-activated protein kinase 264
ERK 202
tyrosinase 122
lactate dehydrogenase 84
protein kinase 53
focal adhesion kinase 51
protein kinase C 28
reverse transcriptase 27
caspase-3 26
DCF 19
proteasome 19
luciferase 17
P-glycoprotein 14
caspase-9 12
PARP 12
collagenase 11
MAP 10
granzyme B 10
urokinase-type plasminogen activator 9
more...
Compound
Clin 501
Dec 450
MEK 324
DNA 304
DIC 122
oxygen 64
tyrosine 54
TNF 44
Interleukin-2 38
Temozolomide 33
serine 30
ATP 28
calcium 28
sulfate 28
BCNU 27
GD3 26
His 26
MTT 25
arginine 25
PEG 24
more...