Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0278488 (metastatic breast cancer)
 7,812 document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
HER2 0.010
hormone receptor 0.003
aromatase 0.002
epidermal growth factor receptor 0.002
estrogen receptor 0.001
DM1 0.001
neu 0.001
CA15 0.001
CDK4 0.000
progesterone receptor 0.000
ESR1 0.000
PIK3CA 0.000
FAC 0.000
PFKP protein 0.000
glucosaminyl (N-acetyl) transferase 2, I-branching enzyme 0.000
RING finger and transmembrane domain-containing protein 1 0.000
mammaglobin 0.000
erbB-2 0.000
CAF 0.000
granulocyte colony-stimulating factor 0.000
RNFT1 0.000
RPS6KC1 0.000
CYTH3 0.000
Triiodothyronine receptor 0.000
RGPD6 0.000
Aromatase 0.000
cyclin-dependent kinase 4 0.000
oestrogen receptor 0.000
DNAJB6 protein 0.000
MOSPD2 0.000
PI3K-C2gamma 0.000
KIAA0368 0.000
CTBP1 protein 0.000
tyrosine kinase 0.000
BRMS1 0.000
TSSC1 0.000
BRMS1L 0.000
T2R10 0.000
breast carcinoma-associated antigen 0.000
IGFN1 0.000
DCST1 0.000
coactivator for steroid receptors 0.000
CORO1B 0.000
DUPD1 0.000
mTOR 0.000
ERBB2 0.000
transmembrane protein 126A 0.000
34KD 0.000
WD repeat domain 1 0.000
metastasis suppressor 0.000
CEA 0.000
CST6 0.000
breast cancer metastasis suppressor 1 0.000
G-CSF 0.000
T2R20 0.000
ABC2 0.000
HDC 0.000
mucin 1 0.000
TTP1 0.000
Bcl-2-associated athanogene 2 0.000
SLC46A3 0.000
thymidine phosphorylase 0.000
FBXO4 0.000
LIM domain kinase 2 0.000
BRMS1 protein 0.000
RRP1B 0.000
phostensin 0.000
heterogeneous nuclear ribonucleoprotein A3 0.000
Estrogen receptor 0.000
PARP 0.000
E-cadherin 0.000
She 0.000
EGFR 0.000
SAM and SH3 domain containing 1 0.000
estrogen receptor coactivator 0.000
G protein-coupled receptor kinase-interactor 1 0.000
MMP-23 0.000
carcinoembryonic antigen 0.000
SIPA1 0.000
PI3K 0.000
more...
Disease
metastatic breast cancer 1.000
breast cancer 0.017
metastases 0.003
neutropenia 0.002
cancer 0.001
hand-foot syndrome 0.001
tumor 0.001
bone metastases 0.001
measurable disease 0.001
myelosuppression 0.001
primary tumor 0.001
recurrent breast cancer 0.001
brain metastases 0.000
leukopenia 0.000
DM1 0.000
evaluable disease 0.000
lung metastases 0.000
inflammatory breast cancer 0.000
MCF 0.000
Metastases to stomach 0.000
carcinoma 0.000
Hand-foot syndrome 0.000
ductal carcinoma 0.000
tumor progression 0.000
thrombocytopenia 0.000
tumor growth 0.000
liver metastases 0.000
stomatitis 0.000
carcinoma of the breast 0.000
lobular breast carcinoma 0.000
Febrile neutropenia 0.000
metastatic uterine cancer 0.000
mammary tumor 0.000
CNS metastases 0.000
HER-2 positive breast cancer 0.000
peripheral neuropathy 0.000
hypercalcemia of malignancy 0.000
Hepar lobatum 0.000
Pseudohyperparathyroidism 0.000
agranulocytosis 0.000
carcinoma of the breast 0.000
infiltrating ductal carcinoma 0.000
breast cancer stage 0.000
sensory neuropathy 0.000
Intra-abdominal metastases 0.000
ovarian cancer 0.000
carcinomatosis 0.000
Desmoplastic trichoepithelioma 0.000
hypercalcemia 0.000
congestive heart failure 0.000
bone disease 0.000
skin metastases 0.000
rash 0.000
ductal carcinoma in situ 0.000
Torus palatinus 0.000
Breast carcinoma 0.000
Ovarian metastasis 0.000
stage II breast cancer 0.000
Intracranial meningioma 0.000
Catheter infection 0.000
bone marrow metastases 0.000
stage III breast cancer 0.000
linitis plastica 0.000
Acute radiation dermatitis 0.000
medullary breast carcinoma 0.000
recurrent neuroblastoma 0.000
Luminal 0.000
anemia 0.000
DPD deficiency 0.000
Disseminated cancer 0.000
PanIN-1B 0.000
stage IV pancreatic cancer 0.000
metastatic gastric cancer 0.000
non-small cell lung cancer 0.000
TTP 0.000
bilateral breast cancer 0.000
Hepatitis B reactivation 0.000
prostate cancer 0.000
Endobronchial metastases 0.000
EMT 0.000
more...
Symptom
nausea 0.000
asthenia 0.000
nausea and vomiting 0.000
bone pain 0.000
diarrhea 0.000
vomiting 0.000
hot flashes 0.000
fatigue 0.000
Negative myoclonus 0.000
axillary pain 0.000
myalgia 0.000
rib pain 0.000
hot flushes 0.000
Flu-like symptoms 0.000
chills 0.000
pain 0.000
vaginal pain 0.000
paresthesia 0.000
Cushingoid 0.000
physical symptom 0.000
Murphy's sign 0.000
arthralgia 0.000
constipation 0.000
dyspnea 0.000
Sister Mary Joseph's nodule 0.000
anorexia 0.000
peau d'orange 0.000
persistent cough 0.000
Scratch 0.000
lightheadedness 0.000
cachexia 0.000
photopsia 0.000
lethargy 0.000
headache 0.000
Flare 0.000
menopausal symptoms 0.000
arm weakness 0.000
erythema 0.000
asterixis 0.000
tenesmus 0.000
Cushingoid 0.000
stomach pain 0.000
inanition 0.000
anal pain 0.000
weakness 0.000
metamorphopsia 0.000
back pain 0.000
periorbital edema 0.000
dizziness 0.000
abdominal discomfort 0.000
night sweats 0.000
No adverse effect 0.000
tonic-clonic seizure 0.000
groin pain 0.000
polyuria 0.000
cancer pain 0.000
testicular pain 0.000
Ill 0.000
discomfort 0.000
discomfort 0.000
muscle cramps 0.000
Depressive symptoms 0.000
blurred vision 0.000
decreased appetite 0.000
flushing 0.000
abdominal pain 0.000
excessive sweating 0.000
bitter taste 0.000
thigh pain 0.000
right upper quadrant pain 0.000
paraparesis 0.000
shoulder pain 0.000
chest tightness 0.000
sleepiness 0.000
hip pain 0.000
rigors 0.000
exertional dyspnea 0.000
epigastric pain 0.000
clubbing 0.000
fever of unknown origin 0.000
more...
Drug
Herceptin 0.009
Ixabepilone 0.003
Docetaxel 0.002
Fulvestrant 0.001
Taxotere 0.001
Vinorelbine 0.001
Xeloda 0.001
Pertuzumab 0.001
Taxol 0.001
DM1 0.001
Navelbine 0.000
Bevacizumab 0.000
Tykerb 0.000
Gemzar 0.000
Arimidex 0.000
Femara 0.000
Adriamycin 0.000
Rostaporfin 0.000
Aromasin 0.000
Everolimus 0.000
Fareston 0.000
Epidoxorubicin 0.000
Fareston 0.000
G-CSF 0.000
Nartograstim 0.000
Filgrastim 0.000
Filgrastim 0.000
GEO 0.000
CTC 0.000
Idoxifene 0.000
Alimta 0.000
Zoledronic acid 0.000
Efaproxiral 0.000
Edatrexate 0.000
Zoledronic acid 0.000
CTC 0.000
Bavituximab 0.000
Torisel 0.000
Novantrone 0.000
Zoladex 0.000
Pemetrexed 0.000
CTX 0.000
Spiegel 0.000
Insulin detemir 0.000
Pirarubicin 0.000
Glutethimide 0.000
Cremophor EL 0.000
Dexrazoxane 0.000
Oncophage 0.000
Zoladex 0.000
Paraplatin 0.000
Ambisome 0.000
CTX 0.000
Satraplatin 0.000
Adozelesin 0.000
Tipifarnib 0.000
Menogaril 0.000
Idarubicin 0.000
Gestrinone 0.000
Pemetrexed disodium 0.000
Ibandronate 0.000
Doxifluridine 0.000
Leucovorin 0.000
2-Methoxyestradiol 0.000
ADM 0.000
Leukine 0.000
Panorex 0.000
Aredia 0.000
Penfluridol 0.000
Vindesine 0.000
Vindesine 0.000
MAP 0.000
Tarceva 0.000
Lenograstim 0.000
CSF 0.000
Etoposide 0.000
Aclarubicin 0.000
Vandetanib 0.000
CTX 0.000
CPT-11 0.000
more...
Enzyme
ERK 0.001
DHAD 0.000
thymidine phosphorylase 0.000
PARP 0.000
focal adhesion kinase 0.000
dihydropyrimidine dehydrogenase 0.000
dihydropyrimidine dehydrogenase 0.000
P-glycoprotein 0.000
urokinase-type plasminogen activator 0.000
MTD 0.000
lysyl oxidase 0.000
phosphatidylinositol-4,5-bisphosphate 3-kinase 0.000
sarcosine dehydrogenase 0.000
MSAS 0.000
cdc2 0.000
mitogen-activated protein kinase 0.000
thymidylate synthase 0.000
6-phosphogluconolactonase 0.000
ALDH 0.000
hydroxyprostaglandin dehydrogenase 0.000
protein kinase 0.000
phosphoinositide 3-kinase 0.000
STK11 0.000
TOR 0.000
GTI 0.000
phosphoserine phosphatase 0.000
topoisomerase 0.000
topoisomerase 0.000
indoleamine 2,3-dioxygenase 0.000
neuropsin 0.000
glycine N-methyltransferase 0.000
N-acetylglucosaminyltransferase V 0.000
alpha-N-acetylgalactosaminidase 0.000
methioninase 0.000
caspase-3 0.000
SNO 0.000
phosphatidylinositol 3-kinase 0.000
CAO 0.000
alkaline phosphatase 0.000
MDR 0.000
CYP3A4 0.000
luciferase 0.000
KLK7 0.000
CEP 0.000
TAT 0.000
NQO2 0.000
phosphatidylserine decarboxylase 0.000
cathepsin D 0.000
MMP 0.000
pregnancy-associated plasma protein-A 0.000
aspartate aminotransferase 0.000
alanine aminotransferase 0.000
PRPP synthetase 0.000
estrogen sulfotransferase 0.000
MEK 0.000
farnesyltransferase 0.000
CEP 0.000
15-hydroxyprostaglandin dehydrogenase 0.000
prostate-specific membrane antigen 0.000
conjugase 0.000
cathepsin K 0.000
AST 0.000
uridine phosphorylase 0.000
deoxycytidine kinase 0.000
phosphoglycerate dehydrogenase 0.000
lactate dehydrogenase 0.000
cytosine deaminase 0.000
6-phosphofructo-2-kinase 0.000
reverse transcriptase 0.000
matrix metalloproteinase 9 0.000
sulfatase 0.000
m-calpain 0.000
dihydrofolate reductase 0.000
hyaluronidase 0.000
farnesyltransferase 0.000
sialyltransferase 0.000
sialyltransferase 0.000
sialyltransferase 0.000
legumain 0.000
caspase-1 0.000
more...
Compound
Capecitabine 0.002
MDA 0.001
Docetaxel 0.001
Paclitaxel 0.001
Tamoxifen 0.000
Tamoxifen 0.000
Anastrozole 0.000
Exemestane 0.000
Gemcitabine 0.000
Gemcitabine 0.000
Epirubicin 0.000
Aminoglutethimide 0.000
Adriamycin 0.000
Mitoxantrone 0.000
Letrozole 0.000
Mitoxantrone 0.000
Megestrol 0.000
5-FU 0.000
Toremifene 0.000
4-methylphenyl benzoate 0.000
Toxol 0.000
folinic acid 0.000
Clin 0.000
NMHE 0.000
ADR 0.000
DMBC 0.000
Toremifene citrate 0.000
MBC 0.000
MBC 0.000
Jatrophone 0.000
CTX 0.000
3-piperidinol 0.000
CAP 0.000
Ifosfamide 0.000
FXM 0.000
CBDCA 0.000
CBDCA 0.000
Borrelidin 0.000
Borrelidin 0.000
BMN 0.000
Rebeccamycin 0.000
Valencene 0.000
EVE 0.000
4-fluorobenzaldehyde 0.000
4-fluorobenzaldehyde 0.000
Dec 0.000
acetate 0.000
VP-16 0.000
Thiotepa 0.000
Droloxifene 0.000
ICRF-187 0.000
MMC 0.000
Cucurbitacin B 0.000
TPTA 0.000
CAM 0.000
C 10 0.000
C 10 0.000
9-cis-Retinoic acid 0.000
Subtilin 0.000
MPA 0.000
MPA 0.000
DNA 0.000
Carminomycin 0.000
Carminomycin 0.000
Estrogen 0.000
MPA 0.000
Tegafur 0.000
Iturin A 0.000
MTS 0.000
Luminal 0.000
2-Methoxyestradiol 0.000
Pamidronate 0.000
Estrogen 0.000
PCNU 0.000
Prednimustine 0.000
Nafoxidine 0.000
TTP 0.000
5-formyltetrahydrofolate 0.000
ONT 0.000
DMAP 0.000
more...