Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0278488 (metastatic breast cancer)
 7,812 document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds) .

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Human Gene/Protein
PFKP protein 12.0
glucosaminyl (N-acetyl) transferase 2, I-branching enzyme 12.0
RING finger and transmembrane domain-containing protein 1 12.0
RPS6KC1 11.0
CYTH3 11.0
RGPD6 11.0
Triiodothyronine receptor 11.0
RNFT1 11.0
CTBP1 protein 10.4
MOSPD2 10.4
KIAA0368 10.4
DNAJB6 protein 10.4
PI3K-C2gamma 10.4
CORO1B 10.0
TSSC1 10.0
DUPD1 10.0
IGFN1 10.0
DCST1 10.0
T2R10 10.0
breast carcinoma-associated antigen 10.0
coactivator for steroid receptors 10.0
BRMS1L 10.0
WD repeat domain 1 9.7
transmembrane protein 126A 9.7
34KD 9.7
T2R20 9.4
TTP1 9.2
Bcl-2-associated athanogene 2 9.2
SLC46A3 9.2
heterogeneous nuclear ribonucleoprotein A3 9.0
FBXO4 9.0
BRMS1 protein 9.0
RRP1B 9.0
phostensin 9.0
LIM domain kinase 2 9.0
G protein-coupled receptor kinase-interactor 1 8.8
MMP-23 8.8
SAM and SH3 domain containing 1 8.8
estrogen receptor coactivator 8.8
breast cancer metastasis suppressor 1 8.8
CA15 8.7
heterogeneous nuclear ribonucleoprotein A/B 8.7
RAD51L2 8.7
SLC2A4RG 8.7
MMP-27 8.7
prune protein 8.7
KIAA1949 8.7
ZNF367 8.7
ZNF207 8.7
AP-2B 8.7
BRMS1 8.6
ABC2 8.6
XIRP2 8.5
HLA-DRB3*01 8.5
UQCRH 8.5
T2R1 8.5
PITPNC1 8.5
CST6 8.5
RASGEF1A 8.5
SIPA1 8.4
PFN2 8.4
YAF2 8.4
focal adhesion kinase 1 8.4
Cyp-D 8.4
RAD51L3 8.4
HER2 8.4
RAD51-like 8.3
PAQR8 8.3
PIK3C2G 8.3
MMP-25 8.3
selectin P 8.3
NUMBL 8.3
WNT5A protein 8.3
HMGN3 8.3
EIF2AK1 8.3
Herstatin 8.3
SFRS3 8.3
T2R14 8.3
histone family member 8.2
Pregnancy zone protein 8.2
more...
Disease
Metastases to stomach 12.0
metastatic breast cancer 12.0
metastatic uterine cancer 10.4
Hepar lobatum 9.4
Pseudohyperparathyroidism 9.2
Intra-abdominal metastases 9.0
Hand-foot syndrome 8.9
hand-foot syndrome 8.9
HER-2 positive breast cancer 8.7
Desmoplastic trichoepithelioma 8.5
evaluable disease 8.4
measurable disease 8.3
Torus palatinus 8.2
recurrent breast cancer 8.1
lobular breast carcinoma 8.1
Intracranial meningioma 8.0
Catheter infection 8.0
Acute radiation dermatitis 7.9
medullary breast carcinoma 7.9
stage IV pancreatic cancer 7.7
PanIN-1B 7.7
Disseminated cancer 7.7
breast cancer stage 7.7
inflammatory breast cancer 7.7
Febrile neutropenia 7.6
recurrent neuroblastoma 7.6
Hepatitis B reactivation 7.5
Ovarian metastasis 7.5
CNS metastases 7.4
stage III breast cancer 7.4
Endobronchial metastases 7.4
Ocular myasthenia 7.1
Adrenal suppression 7.1
bone metastases 7.0
DPD deficiency 7.0
stage II breast cancer 7.0
hypercalcemia of malignancy 7.0
brain metastases 6.9
breast cancer 6.9
Candida pneumonia 6.9
Renal metastasis 6.9
gallbladder empyema 6.9
myelosuppression 6.9
Idiopathic pneumonia syndrome 6.8
bone marrow metastases 6.8
Chemotherapy-induced neutropenia 6.8
AD5 6.8
neutropenia 6.8
linitis plastica 6.8
Skin toxicity 6.7
breast fibroadenoma 6.7
acute rheumatic carditis 6.6
Breast carcinoma 6.6
Extrahepatic cholestasis 6.6
DM1 6.5
recurrent osteosarcoma 6.5
infiltrating ductal carcinoma 6.5
skin metastases 6.4
Purging 6.3
Breast metastases 6.3
lung metastases 6.3
leukopenia 6.3
cecitis 6.2
bilateral breast cancer 6.2
ductal carcinoma 6.2
adenocarcinoma of unknown primary 6.2
carcinoma of the breast 6.2
Bone marrow toxicity 6.1
metastatic gastric cancer 6.1
metastatic ovarian cancer 6.1
onycholysis 6.0
Ductal carcinoma 6.0
metastases 6.0
AIDS-related Kaposi's sarcoma 6.0
ovarian cancer stage 5.9
Reversible posterior leukoencephalopathy syndrome 5.9
primary tumor 5.9
sensory neuropathy 5.9
acute thyroiditis 5.9
carcinoma of the breast 5.8
more...
Symptom
Negative myoclonus 8.5
axillary pain 7.8
rib pain 7.5
Flu-like symptoms 7.2
vaginal pain 6.4
hot flashes 6.3
asthenia 6.2
Murphy's sign 6.1
bone pain 5.9
Cushingoid 5.8
Sister Mary Joseph's nodule 5.8
physical symptom 5.6
peau d'orange 5.5
hot flushes 5.4
nausea and vomiting 5.2
Scratch 5.0
photopsia 4.9
nausea 4.9
persistent cough 4.7
lightheadedness 4.6
Flare 4.5
arm weakness 4.5
myalgia 4.4
chills 4.3
asterixis 4.3
Cushingoid 4.3
inanition 4.2
anal pain 4.1
tenesmus 4.1
vomiting 4.1
metamorphopsia 4.1
stomach pain 4.0
periorbital edema 4.0
paresthesia 4.0
diarrhea 3.8
No adverse effect 3.7
menopausal symptoms 3.6
testicular pain 3.6
arthralgia 3.5
fatigue 3.5
groin pain 3.4
night sweats 3.4
constipation 3.3
abdominal discomfort 3.2
tonic-clonic seizure 3.2
muscle cramps 3.2
cachexia 3.1
lethargy 3.0
anorexia 2.8
excessive sweating 2.8
decreased appetite 2.8
polyuria 2.7
cancer pain 2.7
Depressive symptoms 2.6
thigh pain 2.6
right upper quadrant pain 2.6
blurred vision 2.6
bitter taste 2.5
dyspnea 2.5
chest tightness 2.4
rigors 2.3
erythema 2.2
dizziness 2.2
clubbing 2.2
hip pain 2.2
paraparesis 2.1
shoulder pain 2.1
back pain 2.1
dry skin 2.0
fever of unknown origin 2.0
flushing 1.9
polydipsia 1.9
Ill 1.9
exertional dyspnea 1.8
epigastric pain 1.8
dental pain 1.8
muscle stiffness 1.7
tachypnea 1.7
masculinization 1.7
Neuropathic pain 1.5
more...
Drug
Rostaporfin 12.0
Ixabepilone 11.1
Pertuzumab 9.9
Xeloda 9.8
Tykerb 9.8
Nartograstim 9.7
Fareston 9.6
Aromasin 9.5
Fareston 9.5
Herceptin 9.5
Femara 9.4
Fulvestrant 9.4
Vinorelbine 9.1
Navelbine 9.1
Efaproxiral 9.0
Taxotere 8.9
Gemzar 8.9
Bavituximab 8.8
Idoxifene 8.8
Arimidex 8.8
Epidoxorubicin 8.8
Torisel 8.7
Edatrexate 8.6
Docetaxel 8.4
Alimta 8.0
DM1 7.9
Glutethimide 7.9
Oncophage 7.8
Taxol 7.6
Insulin detemir 7.5
Pirarubicin 7.5
Paraplatin 7.4
Bevacizumab 7.4
Satraplatin 7.2
Ambisome 7.2
Adozelesin 7.2
Novantrone 7.2
Everolimus 7.1
Filgrastim 7.1
Filgrastim 7.0
Menogaril 7.0
Gestrinone 7.0
Spiegel 6.9
Dexrazoxane 6.9
Zoladex 6.9
Pemetrexed disodium 6.9
Tipifarnib 6.9
Zoledronic acid 6.7
Doxifluridine 6.7
Pemetrexed 6.7
Zoladex 6.6
Leukine 6.5
Panorex 6.5
Zoledronic acid 6.4
Aredia 6.4
Penfluridol 6.3
CTC 6.3
Ibandronate 6.3
Idarubicin 6.3
Lenograstim 6.3
2-Methoxyestradiol 6.2
Aclarubicin 6.2
Adriamycin 6.2
Cremophor EL 6.2
Vindesine 6.1
Vindesine 6.1
GEO 6.1
CTC 6.1
Dextropropoxyphene 6.0
Vandetanib 5.9
Evista 5.9
Cilengitide 5.8
Fosamax 5.8
Tarceva 5.8
Trabectedin 5.8
Velban 5.8
Gallium nitrate 5.7
Leucovorin 5.6
CDX 5.6
Lovenox 5.5
more...
Enzyme
DHAD 8.3
thymidine phosphorylase 6.3
sarcosine dehydrogenase 6.2
MSAS 6.1
phosphatidylinositol-4,5-bisphosphate 3-kinase 5.9
dihydropyrimidine dehydrogenase 5.7
6-phosphogluconolactonase 5.5
ERK 5.5
hydroxyprostaglandin dehydrogenase 5.4
MTD 5.4
dihydropyrimidine dehydrogenase 5.3
GTI 5.1
phosphoserine phosphatase 4.9
lysyl oxidase 4.9
STK11 4.7
neuropsin 4.7
N-acetylglucosaminyltransferase V 4.7
glycine N-methyltransferase 4.7
alpha-N-acetylgalactosaminidase 4.7
methioninase 4.6
CAO 4.6
ALDH 4.5
KLK7 4.5
SNO 4.4
NQO2 4.4
phosphatidylserine decarboxylase 4.4
PARP 4.3
pregnancy-associated plasma protein-A 4.3
PRPP synthetase 4.1
estrogen sulfotransferase 4.1
TOR 4.1
CEP 4.0
conjugase 3.8
indoleamine 2,3-dioxygenase 3.8
thymidylate synthase 3.8
uridine phosphorylase 3.7
15-hydroxyprostaglandin dehydrogenase 3.7
phosphoglycerate dehydrogenase 3.7
6-phosphofructo-2-kinase 3.6
farnesyltransferase 3.6
deoxycytidine kinase 3.5
urokinase-type plasminogen activator 3.5
CEP 3.5
cytosine deaminase 3.4
cdc2 3.4
legumain 3.4
P-glycoprotein 3.4
TAT 3.4
m-calpain 3.3
succinyl-CoA synthetase 3.3
phosphoinositide 3-kinase 3.3
prostate-specific membrane antigen 3.2
caspase-7 3.2
caspase-7 3.1
cathepsin K 3.1
MDR 3.1
cathepsin S 3.0
farnesyltransferase 3.0
sialyltransferase 3.0
focal adhesion kinase 3.0
sialyltransferase 3.0
sialyltransferase 3.0
cathepsin D 3.0
TRS 3.0
MMP 2.9
dihydropteroate synthase 2.9
matrix metalloproteinase 9 2.9
meprin 2.9
estrogen sulfotransferase 2.9
GRK5 2.9
CYP3A4 2.8
serine hydroxymethyltransferase 2.8
arylsulfatase 2.7
topoisomerase 2.7
factor C 2.7
sulfatase 2.7
topoisomerase 2.6
neutral sphingomyelinase 2.6
glutathione synthetase 2.6
phosphatidylinositol 4-kinase 2.6
more...
Compound
Megestrol 9.8
4-methylphenyl benzoate 9.7
Toxol 9.7
Capecitabine 9.6
Exemestane 8.8
Anastrozole 8.7
DMBC 8.7
Toremifene citrate 8.7
NMHE 8.4
Jatrophone 8.4
Aminoglutethimide 8.4
3-piperidinol 8.2
Docetaxel 8.2
Toremifene 8.1
Epirubicin 8.0
Letrozole 7.8
FXM 7.7
Borrelidin 7.6
Borrelidin 7.5
Valencene 7.5
Rebeccamycin 7.5
4-fluorobenzaldehyde 7.4
Mitoxantrone 7.4
4-fluorobenzaldehyde 7.3
Paclitaxel 7.3
BMN 7.2
Mitoxantrone 7.2
Droloxifene 7.1
Gemcitabine 7.1
Gemcitabine 7.0
TPTA 6.9
EVE 6.9
Tamoxifen 6.9
Tamoxifen 6.9
Subtilin 6.9
9-cis-Retinoic acid 6.9
Carminomycin 6.8
Carminomycin 6.8
Cucurbitacin B 6.8
Iturin A 6.7
Prednimustine 6.5
PCNU 6.5
Thiotepa 6.5
MDA 6.4
Nafoxidine 6.4
C 10 6.4
C 10 6.4
ICRF-187 6.3
Ifosfamide 6.3
Brazilin 6.3
2-Methoxyestradiol 6.2
ONT 6.2
Velban 6.1
Leuprolide 6.0
Kryptofix 2.2 6.0
folinic acid 6.0
ICI 164384 5.9
Pamidronate 5.9
AZQ 5.9
Adriamycin 5.8
Costunolide 5.8
Tegafur 5.8
C 6 5.8
phenyl carbamate 5.7
Cesium chloride 5.7
Medroxyprogesterone 5.7
Temsirolimus 5.6
Hydromorphone 5.6
Trimetrexate 5.6
MBC 5.6
CLS 5.5
MBC 5.5
9-AC 5.5
Withaferin A 5.5
Deoxypyridinoline 5.5
Risedronate 5.5
5-formyltetrahydrofolate 5.5
Elan 5.5
CBDCA 5.4
CBDCA 5.4
more...