Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts: Gene/Protein Disease Symptom Drug Enzyme Compound   Target Concepts: Gene/Protein Disease Symptom Drug Enzyme Compound

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Query: UMLS:C0278488 (metastatic breast cancer)
7,812 document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .

Human Gene/Protein HER2 1013 epidermal growth factor receptor 535 estrogen receptor 503 Sep 455 hormone receptor 391 aromatase 356 Mol 277 tyrosine kinase 167 progesterone receptor 166 She 143 neu 139 mTOR 124 CDK4 105 vascular endothelial growth factor 99 DM1 95 albumin 94 PI3K 89 granulocyte colony-stimulating factor 86 erbB-2 79 E-cadherin 75 cytokine 74 EGFR 71 p53 70 nodal 68 AKT 64 VEGF 63 PARP 63 epidermal growth factor 63 PIK3CA 62 ESR1 58 collagen 55 CEA 54 BRCA1 54 carcinoembryonic antigen 53 granulocyte 51 oestrogen receptor 50 G-CSF 50 Aromatase 45 CD44 45 CD8 44 more...

Disease metastatic breast cancer 7812 breast cancer 4590 cancer 3299 tumor 2351 metastases 1588 neutropenia 470 carcinoma 449 primary tumor 294 tumor growth 245 MCF 224 tumor progression 218 bone metastases 206 thrombocytopenia 181 myelosuppression 169 leukopenia 139 brain metastases 132 ovarian cancer 104 lung metastases 102 anemia 101 prostate cancer 97 DM1 95 lung cancer 93 liver metastases 92 tumorigenesis 91 stomatitis 89 congestive heart failure 84 peripheral neuropathy 80 hand-foot syndrome 77 adenocarcinoma 71 colorectal cancer 69 ductal carcinoma 68 rash 67 mammary tumor 65 melanoma 65 measurable disease 63 non-small cell lung cancer 62 multiple myeloma 58 neuropathy 58 recurrent breast cancer 55 hypercalcemia 55 more...

Symptom diarrhea 190 nausea 171 pain 170 fatigue 140 vomiting 132 nausea and vomiting 88 asthenia 49 bone pain 47 dyspnea 39 headache 35 myalgia 33 constipation 24 anorexia 24 weakness 24 chills 21 hot flashes 20 arthralgia 20 paresthesia 19 discomfort 15 erythema 15 abdominal pain 14 discomfort 14 back pain 13 hot flushes 13 cachexia 12 dizziness 11 lethargy 11 Ill 10 analgesia 8 starvation 8 cough 7 sleepiness 7 anesthesia 7 flushing 6 seizures 6 cancer pain 5 insomnia 5 ataxia 5 chest pain 5 polyuria 5 more...

Drug Herceptin 395 Taxol 149 Docetaxel 145 DM1 96 Adriamycin 82 Bevacizumab 74 Taxotere 74 Vinorelbine 59 Fulvestrant 57 G-CSF 54 CTX 52 CSF 46 Ixabepilone 45 Xeloda 35 MAP 33 Pertuzumab 32 CTX 28 GEO 26 Everolimus 24 Navelbine 24 Gemzar 22 CTC 21 CTC 21 Dermatol 18 CTX 18 Zoledronic acid 17 ADM 16 Arimidex 16 lysine 16 ICI 16 IL-2 14 Filgrastim 13 Zoledronic acid 13 Tykerb 12 Filgrastim 12 Cremophor EL 11 Femara 10 CPT-11 10 Pemetrexed 10 EE2 10 more...

Enzyme ERK 1030 focal adhesion kinase 86 mitogen-activated protein kinase 71 PARP 65 protein kinase 55 P-glycoprotein 34 alkaline phosphatase 32 urokinase-type plasminogen activator 29 luciferase 28 caspase-3 28 ACS 25 cdc2 22 thymidine phosphorylase 20 alanine aminotransferase 20 lactate dehydrogenase 18 aspartate aminotransferase 18 reverse transcriptase 18 MEK 16 topoisomerase 15 topoisomerase 15 phosphatidylinositol 3-kinase 15 phosphoinositide 3-kinase 14 proteasome 14 thymidylate synthase 12 dihydropyrimidine dehydrogenase 12 CYP3A4 11 dihydropyrimidine dehydrogenase 10 ATPase 10 protein kinase C 9 MDR 9 lysyl oxidase 9 MMP 8 AST 8 cathepsin D 8 collagenase 7 dihydrofolate reductase 7 GSK 7 caspase-1 7 MTD 6 caspase-9 6 more...

Compound Clin 841 Dec 556 MDA 516 DNA 295 acetate 130 Adriamycin 116 Paclitaxel 113 Tamoxifen 108 Tamoxifen 102 Docetaxel 97 Capecitabine 96 5-FU 74 calcium 58 tyrosine 55 Gemcitabine 54 Gemcitabine 54 CTX 52 ADR 46 glucose 45 oxygen 42 PEG 36 water 36 CAM 33 MTT 32 Estrogen 30 ATP 29 CAP 29 Estrogen 29 folinic acid 27 Mitoxantrone 26 MBC 26 MBC 26 ACS 25 ACS 25 Epirubicin 25 sulfate 25 sodium 23 Mitoxantrone 23 Progesterone 23 MAP 22 more...

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