Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0278488 (metastatic breast cancer)
7,812 document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
HER2 1013
epidermal growth factor receptor 535
estrogen receptor 503
Sep 455
hormone receptor 391
aromatase 356
Mol 277
tyrosine kinase 167
progesterone receptor 166
She 143
neu 139
mTOR 124
CDK4 105
vascular endothelial growth factor 99
DM1 95
albumin 94
PI3K 89
granulocyte colony-stimulating factor 86
erbB-2 79
E-cadherin 75
more...
Disease
metastatic breast cancer 7812
breast cancer 4590
cancer 3299
tumor 2351
metastases 1588
neutropenia 470
carcinoma 449
primary tumor 294
tumor growth 245
MCF 224
tumor progression 218
bone metastases 206
thrombocytopenia 181
myelosuppression 169
leukopenia 139
brain metastases 132
ovarian cancer 104
lung metastases 102
anemia 101
prostate cancer 97
more...
Symptom
diarrhea 190
nausea 171
pain 170
fatigue 140
vomiting 132
nausea and vomiting 88
asthenia 49
bone pain 47
dyspnea 39
headache 35
myalgia 33
constipation 24
weakness 24
anorexia 24
chills 21
hot flashes 20
arthralgia 20
paresthesia 19
erythema 15
discomfort 15
more...
Drug
Herceptin 395
Taxol 149
Docetaxel 145
DM1 96
Adriamycin 82
Taxotere 74
Bevacizumab 74
Vinorelbine 59
Fulvestrant 57
G-CSF 54
CTX 52
CSF 46
Ixabepilone 45
Xeloda 35
MAP 33
Pertuzumab 32
CTX 28
GEO 26
Everolimus 24
Navelbine 24
more...
Enzyme
ERK 1030
focal adhesion kinase 86
mitogen-activated protein kinase 71
PARP 65
protein kinase 55
P-glycoprotein 34
alkaline phosphatase 32
urokinase-type plasminogen activator 29
caspase-3 28
luciferase 28
ACS 25
cdc2 22
alanine aminotransferase 20
thymidine phosphorylase 20
lactate dehydrogenase 18
aspartate aminotransferase 18
reverse transcriptase 18
MEK 16
topoisomerase 15
topoisomerase 15
more...
Compound
Clin 841
Dec 556
MDA 516
DNA 295
acetate 130
Adriamycin 116
Paclitaxel 113
Tamoxifen 108
Tamoxifen 102
Docetaxel 97
Capecitabine 96
5-FU 74
calcium 58
tyrosine 55
Gemcitabine 54
Gemcitabine 54
CTX 52
ADR 46
glucose 45
oxygen 42
more...