Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C0278488 (
metastatic breast cancer
)
7,812
document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
HER2
1013
epidermal growth factor receptor
535
estrogen receptor
503
Sep
455
hormone receptor
391
aromatase
356
Mol
277
tyrosine kinase
167
progesterone receptor
166
She
143
neu
139
mTOR
124
CDK4
105
vascular endothelial growth factor
99
DM1
95
albumin
94
PI3K
89
granulocyte colony-stimulating factor
86
erbB-2
79
E-cadherin
75
more...
Disease
metastatic breast cancer
7812
breast cancer
4590
cancer
3299
tumor
2351
metastases
1588
neutropenia
470
carcinoma
449
primary tumor
294
tumor growth
245
MCF
224
tumor progression
218
bone metastases
206
thrombocytopenia
181
myelosuppression
169
leukopenia
139
brain metastases
132
ovarian cancer
104
lung metastases
102
anemia
101
prostate cancer
97
more...
Symptom
diarrhea
190
nausea
171
pain
170
fatigue
140
vomiting
132
nausea and vomiting
88
asthenia
49
bone pain
47
dyspnea
39
headache
35
myalgia
33
constipation
24
weakness
24
anorexia
24
chills
21
hot flashes
20
arthralgia
20
paresthesia
19
erythema
15
discomfort
15
more...
Drug
Herceptin
395
Taxol
149
Docetaxel
145
DM1
96
Adriamycin
82
Taxotere
74
Bevacizumab
74
Vinorelbine
59
Fulvestrant
57
G-CSF
54
CTX
52
CSF
46
Ixabepilone
45
Xeloda
35
MAP
33
Pertuzumab
32
CTX
28
GEO
26
Everolimus
24
Navelbine
24
more...
Enzyme
ERK
1030
focal adhesion kinase
86
mitogen-activated protein kinase
71
PARP
65
protein kinase
55
P-glycoprotein
34
alkaline phosphatase
32
urokinase-type plasminogen activator
29
caspase-3
28
luciferase
28
ACS
25
cdc2
22
alanine aminotransferase
20
thymidine phosphorylase
20
lactate dehydrogenase
18
aspartate aminotransferase
18
reverse transcriptase
18
MEK
16
topoisomerase
15
topoisomerase
15
more...
Compound
Clin
841
Dec
556
MDA
516
DNA
295
acetate
130
Adriamycin
116
Paclitaxel
113
Tamoxifen
108
Tamoxifen
102
Docetaxel
97
Capecitabine
96
5-FU
74
calcium
58
tyrosine
55
Gemcitabine
54
Gemcitabine
54
CTX
52
ADR
46
glucose
45
oxygen
42
more...