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Query: UMLS:C0278134 (anesthesia)
 110,339 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Cryopreserved, autologous stem cells collected from human marrow have been used to accelerate hematopoietic recovery following intensive radiation or chemotherapy. The harvesting of adequate numbers of bone marrow cells for purposes of hematopoietic reconstitution is a potentially morbid procedure and requires the use of general anesthesia and blood transfusion during anesthesia. The ability to accelerate hematopoietic recovery using cells collected solely from the peripheral blood would obviate the requirement for a general anesthetic and avoid the discomfort experienced by patients following the procedure. Collection of hematopoietic stem cells from the peripheral blood should involve limited morbidity and risk and be well suited to repeated application in individual cases. An increasing body of in vitro and in vivo data in animals and man suggests that this goal may soon be within reach.
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PMID:Prospects for accelerating hematopoietic recovery following myelosuppressive therapy by using autologous, cryopreserved hematopoietic stem cells collected solely from the peripheral blood. 4 55

A randomized double-blind study of 100 patients was done, using 4% lidocaine and/or saline applied to the fallopian tubes at the time of tubal fulguration by laparoscopy. Lidocaine was shown statistically to be effective in reducing the discomfort the patient experiences when the procedure is carried out under local anesthesia as an outpatient.
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PMID:The application of lidocaine to the fallopian tubes during tubal fulguration by laparoscopy. 13 May 74

Peritoneoscopy was carried out in 352 cancer patients with clinical suspicion of liver involvement in most cases. Principally because of patient discomfort, adequate liver biopsy was obtained in only 66% of 240 patients who underwent peritoneoscopy under local anesthesia while, under general anesthesia, biopsies could be taken in 90% of 112 patients. When the liver was macroscopically free of disease, the yield of positive peritoneoscopy was minimal regardless of the number of blind deep biopsies. Peritoneoscopy provided histologic demonstration of hepatic invasion in a total of 55 patients. Seven false-negative examinations out of 19 negative peritoneoscopies (36%) were identified by subsequent laparotomy or autopsy within 2 months. These preliminary data, although difficult to interpret in terms of accuracy of the method, point to the possible contributions of peritoneoscopy in detecting liver metastases.
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PMID:The use of peritoneoscopy in the detection of liver metastases. 14 27

Laparoscopy is a simple and sure method of diagnosis for the gastroenterologist. Laparascopy does not oppose exploratory laparatomy and can often substitute it advantageously. In fact it causes less morbility and mortality, less discomfort to the patient, requires only local anesthesia, permits leaving the hospital within 4 hours, and when done by an experienced and able person provides data of great usefulness in diagnosis, prognosis, and treatment. A laparoscopy can confirm or refute various doubtful clinical diagnoses. It is hoped that the thecnic demonstrated and seen through the laparoscopy will lead to a greater use of this valuable diagnostic examination.
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PMID:[Abdominal laparoscopy, experience in 1,400 cases studied]. 14 92

The author questions the conventional assumption that the pneumoperitoneum must be established before insertion of the laparoscope and its trocar. Complications commonly associated with establishment of a needle-induced pneumoperitoneum include subcutaneous emphysema, blood vessel penetration, retroperitoneal emphysema, bowel distention, overdistention, gas embolism, and omental emphysema. This paper summarizes the author's experience with 301 outpatient laparoscopies performed in 1976-77 using the method of direct trocar insertion without prior pneumoperitoneum. The process of pneumoperitoneum was visualized directly through the Needlescope. 54 cases were performed under general anesthesia and 247 under local anesthesia. Complications were encountered in only 3 cases (1 uterine perforation and 2 cases requiring postoperative hospitalization for nausea and vomiting). There were no cases of technical failure. Comparison of recovery times for 250 consecutive patients treated without preliminary pneumoperitoneum and 117 patients treated with the conventional technique indicated that the recovery time was 19 minutes shorter on average in the former group because of a lessened degree of postoperative discomfort, nausea, and vomiting. Although further research is necessary to confirm the findings in this series, it seems plausible to suggest that a reduction of complications associated with needle-induced pneumoperitoneum may be possible with this technique.
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PMID:Direct laparoscope trocar insertion without prior pneumoperitoneum. 15 Nov 44

Epidermolysis bullosa dystrophica is a rare disease that affects the skin and mucous membranes. Manifest at birth, it is characterized by poor dentition, esophageal strictures, syndactyly, and severe chronic anemia. Our 12-year-old patient required extensive dental treatment which necessitated overcoming problems of anesthesia as well as developing a technique of management that provided maximum safety and a minimum of discomfort. Transmission electron microscopy of sections of the gingiva revealed possible degenerative collagen fibers and an interrupted basement membrance. Anchoring fibrils normally found in the connective tissue beneath the epithelium were absent.
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PMID:Epidermolysis bullosa dystrophica polydysplastica. A case of anesthetic management in oral surgery. 26 79

The value of rubber band ligation in the treatment of haemorrhoids is discussed and the literature on the case histories of 3244 patients who were treated by this technique is reviewed. 36% of the patients found this form of therapy to be painless, 41% suffered little and 14% severe pain. 80% of all patients finally were free of symptoms. Rubber band ligation therefore is an effective method treating internal haemorrhoids. Its advantages are simplicity, relatively little discomfort for the patient, applicability in ambulant patients, no general anaesthesia, low cost and good results with only minor complications. Thus it is an alternative to sclerotherapy and to surgical haemorrhoidectomy.
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PMID:[Ambulatory hemorrhoidectomy through rubber band ligation-review of the literature]. 30 45

As vasectomy continues in popularity, requests for restoration of fertility increase in number. Anastomosis of the vas deferens is a demanding, technically difficult operation. The principles governing it are different from those of other anastomoses in the body. The suitably equipped surgeon can expect, with practice, to achieve a pregnancy rate of 50% or better for his patient's wife. The operation can easily be performed under local anesthesia in either an office or hospital operating room. Hospitalization is unnecessary, and merely adds unnecessary expense. Disability is minimal, and discomfort minor. The technique of Belker is recommended for practice, since it permits one to inspect the anastomosis from within afterwards.
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PMID:Vasovasostomy. 36 50

Three hundred fifty-seven groin hernia repairs were performed under local anesthesia using a long-lasting local anesthetic agent. An ilioinguinal, iliohypogastric, and twelfth intercostal nerve block was carried out initially, followed by regional infiltration of the agent, using a technic first described by Ponka [8] with several modifications. This technic can be employed suffessfully in the majority of groin hernia repairs. It requires careful attention to detail in the administration of preoperative sedation and analgesia and the use of sharp dissection only and greater gentleness in the handling of tissue. We have observed a significant reduction in postoperative discomfort and the virtual elimination of urinary retention, urinary sepsis, atelectasis, and phlebitis in these cases. All patients are fully ambulatory, without assistance immediately after surgery and the majority are discharged the same day or the following morning. This results in a marked reduction in the total cost of repairing a groin hernia.
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PMID:Change in the management of adult groin hernia. 41 25

Four patients with typical renovascular hypertension due to atherosclerotic stenosis (3 patients) and near occlusion (one patient) were treated with percutaneous transluminal angioplasty (PTA). Two patients had malignant hypertension by clinical standards. All had significant reduction in blood pressure following angioplasty, resulting in either a normotensive state, or management with significantly less antihypertensive medication. Patency and normal renin levels were achieved within two months in 2 patients. Clinical follow-up documented continued reduction in blood pressure. Advantages of the procedure include local anesthesia, relatively little discomfort, repeatability, and the fact that surgery is not precluded if angioplasty is unsuccessful.
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PMID:Percutaneous transluminal angioplasty for treatment of renovascular hypertension. 42 6


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