Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0278134 (anesthesia)
110,339 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

An elderly woman who had spinal epidural anesthesia thereafter had headache, anorexia, nausea and vomiting, dehydration, seizures, and cardiovascular collapse. CAT scan revealed air in the posterior fossa, probably caused by intradural injection of air during epidural anesthesia. We propose that this may be an occasional cause of headache or more substantial complications after epidural anesthesia, and suggest that CAT scanning may be helpful in identifying this complication.
...
PMID:Pneumocephaly from epidural anesthesia. 682 9

100 patients who have had bilateral tubal ligation using a local anesthetic technique within 7 days of the delivery of their last child and 100 patients who have had the operation performed using general anesthesia were studied in the postoperative period to determine the incidence and nature of complications. The latter group comprised of 50 patients who underwent surgery within 7 days of delivery (general anesthesia postpartum group) and 50 patients who had their last child more than 7 days prior to the operation (general anesthesia interval group). There was no significant difference between the overall incidence of complications between the local anesthesia group and the general postpartum group. The general anesthesia interval group, however, had significantly more complications. The patients in the local anesthesia group complained of more pain in their back and legs while patients in both the general anesthesia groups had more pain in the upper limb and chest muscles. Complications included anorexia, nausea, vomiting, headache, and aches and pains.
...
PMID:Minor complications relevant to anaesthetic technique following bilateral tubal ligation. 718 1

Cadmium (Cd) loading trials were conducted on a total of 110 (3 x 10 and 4 x 20) broiler chickens prereared for 21 days. The control chickens received no cadmium, while chickens in the six treatment groups were given different doses of Cd as an aqueous solution of CdSO4 administered either into the crop or mixed in the feed. The chickens were kept in a climatized animal house and treated usually for 3-5 weeks (maximum 68 days), with the exception of group Cd-75 chickens which were treated up to 239 days of age. The chickens' health status, body mass and feed consumption were monitored throughout the trial. On days 14-20 and on day 42 of the trial 2 chickens per group, then at the end of trial a total of 25 chickens were killed in anaesthesia. These birds, together with chickens that died or were killed during the trial, were subjected to detailed gross pathological examination. From 11 organs (kidney, liver, spleen, testicle, brain, myocardium, skeletal muscle, lungs, digestive tract, pancreas, tubular bones) of these chickens samples were taken for assay for a total of 16 elements, as well as for light and electron microscopic examination. With the exception of groups Cd-30 and Cd-600, no abnormal clinical signs were observed in the first two weeks of the trial. Chickens of group Cd-30 died before day 8-12 of the trial among signs of complete anorexia, rapid emaciation, huddling and diarrhoea, while chickens of group Cd-600 died before day 28, showing similar clinical signs. The body mass of chickens fed a Cd-supplemented diet either remained constant or decreased substantially, in a degree proportional to the Cd load. The only exception was group Cd-2.5, in which the average body mass of birds at the end of week 8 slightly exceeded that of the controls. Four out of the 10 cockerel chicks fed a diet containing 75 ppm Cd up to 239 days of age died of intercurrent diseases; the remaining six grew well and reached a body mass of 3.8-4.3 kg. Feed conversion efficiency was satisfactory in the control group and in group Cd-2.5 (2.1 and 2.4 kg, respectively) and could not be evaluated in a realistic manner in the other groups. At necropsy, the cockerel chicks of groups Cd-30 and Cd-600 showed severe emaciation, liver and kidney degeneration, myocardial hypertrophy and cardiac dilatation.(ABSTRACT TRUNCATED AT 400 WORDS)
...
PMID:Complex study of the physiological role of cadmium. III. Cadmium loading trials on broiler chickens. 749 61

This study investigated the potential for multiple exposures of propofol to induce oxidative injury, in the form of Heinz body production, to feline red blood cells. Anesthesia was induced in six healthy cats with propofol (6 mg/kg, intravenous [IV]) and maintained for 30 minutes with a propofol infusion (0.20 to 0.30 mg/kg/min, IV). The initial protocol was designed for each cat to receive 10 consecutive days of propofol anesthesia. All cats spontaneously breathed room air. Heart rate, respiratory rate, and indirect blood pressure were measured and recorded before and during anesthesia. Time to complete recovery after each infusion was measured and recorded. Heinz body analysis was performed before and after each day of propofol anesthesia. Based on predetermined criteria for discontinuing daily infusions, the mean number of consecutive days of propofol anesthesia was six and propofol administration did not continue beyond 7 days in any cat. Heart rate, respiratory rate, and indirect blood pressure did not change significantly during propofol anesthesia compared with awake values. Following the third consecutive day of propofol anesthesia, there was a significant increase from baseline in the mean percentage of Heinz bodies. Hemolysis was not detected in any cat. Recovery time significantly increased after the second consecutive day of propofol anesthesia compared with the first day. Five of six cats developed generalized malaise, anorexia, and diarrhea on day 5, 6, or 7, and two cats developed facial edema.(ABSTRACT TRUNCATED AT 250 WORDS)
...
PMID:The effects of consecutive day propofol anesthesia on feline red blood cells. 765 43

An alpaca and a llama in late stages of gestation were evaluated for lethargy, anorexia, and recumbency. Both camelids had cloudy, white, turbid serum, elevated serum triglyceride (1564, 5658 mg/dL, respectively) and cholesterol (158, 297 mg/dL, respectively) concentrations, and ketonuria. Signs of fetal stress were evident ultrasonographically in the alpaca, and a live cria was delivered by Cesarean section performed under general anesthesia. The alpaca developed severe metabolic acidosis, hepatic lipidosis, and acute renal failure secondary to renal lipidosis and died 36 hours after admission despite medical therapy. Histopathology revealed renal and hepatic lipidosis and neutrophilic pancreatitis. The cria died 72 hours after birth. The llama responded to IV electrolyte, dextrose, and regular crystalline insulin therapy. The pregnancy was maintained, and the llama was discharged from the hospital 20 days after admission. Two months after discharge, the llama gave birth to a live, 5 kg cria. Findings of hypertriglyceridemia, hypercholesterolemia, elevated sorbitol dehydrogenase activity, metabolic acidosis, azotemia, and ketonuria occurred in these two camelids. Based on this report, camelids appear to be similar to both horses and cattle in their response to severe energy imbalances in late gestation.
...
PMID:Hyperlipemia and ketonuria in an alpaca and a llama. 806 56

We report a case of suspected liver dysfunction after general anesthesia with sevoflurane. A 30 day old male infant underwent inguinal herniorrhaphy under sevoflurane anesthesia (sevoflurane concentration: 1.3-1.5% with 50% oxygen and nitrous oxide). Two days after the operation, he developed frequent vomiting, anorexia and fever. GOT, GPT and LDH values were 242 Ku, 326 Ku and 901 Wu, respectively and peaked at 520 Ku, 709 Ku and 1000 Wu 12-16 days after the operation. Clinical symptoms and the laboratory data became normal within 2 months. The antibody titers of EB-virus, cytomegalo-virus and HA-virus were all within normal ranges and HBs antigen was negative. There were no blood transfusion or antibiotics administration before the onset, and no epidemic of hepatitis around him. His mother had no history of hepatitis during her pregnancy. Lymphocyte stimulation test for indication of sevoflurane allergy was also negative. From these evidences, toxic (not allergic) liver dysfunction due to exposure to sevoflurane was considered to be the most probable diagnosis.
...
PMID:[A case of suspected liver dysfunction induced by sevoflurane anesthesia]. 832 Aug 10

Anorexia nervosa is a chronic illness characterized by a severe loss of weight. It occurs in children and young adults and is seen more frequently in females. Some anorexic patients refuse to eat totally, while others may practice "binge eating." Patients who binge eat and employ postprandial purging are referred to as "bulimic." Anorexia nervosa and bulimia can produce multisystem abnormalities. Dysfunction of organ systems in anorexia is the result of self-induced vomiting, laxative abuse, and severe malnutrition. Diseases of the skeletal, gastrointestinal, pulmonary, endocrine, and cardiovascular systems may have an impact on the plan of anesthesia care. A thorough anesthetic interview and evaluation to assess the debilitation of each patient is essential so that appropriate preparation can be made for comprehensive anesthetic care. This paper focuses on the pathophysiology of anorexia nervosa, discusses a thorough preanesthetic assessment, and guides the appropriate anesthetic management of the anorexic patient. Anorexia bulimia is briefly mentioned, since it is an eating disorder with physiological derangements similar to anorexia nervosa.
...
PMID:Anesthetic considerations with anorexia nervosa. 837 78

The aim of this study was to evaluate the role of renal ammonia and glutamine metabolism in the metabolic adaptation to chronic liver insufficiency-induced hyperammonemia in the rat. To this purpose, urinary excretion, renal net exchange and tissue concentrations of ammonia and amino acids were measured in anesthetized, normal control rats that did not undergo surgery, in control rats that underwent sham surgery, in rats that underwent portacaval shunting and in rats that underwent both portacaval shunting and bile duct ligation. Rats that underwent sham surgery and portacaval shunting were pair-fed with rats that underwent portacaval shunting and biliary obstruction, to correct for anorexia in that group, and all rats that were operated on were studied 7 and 14 days after surgery. Arterial ammonia and glutamine levels were elevated in groups that underwent portacaval shunting and portacaval shunting plus biliary obstruction at all time points. At days 7 and 14, total renal ammonia production decreased in rats that underwent portacaval shunting and in rats that underwent portacaval shunting plus biliary obstruction, associated with a 50% decrease in net renal glutamine uptake and strongly diminished net ammonia release into the renal vein, which was most prominent in the group that underwent portacaval shunting plus biliary obstruction. Urinary ammonia excretion was similar in rats that underwent portacaval shunting and in those that underwent sham surgery but was increased more than 200% at days 7 and 14 in rats that underwent portacaval shunting plus biliary obstruction. In this group, in contrast to portacaval-shunted rats, the kidney appeared to be an organ of net ammonia disposal from the body. In separate experiments in unanesthetized, unrestrained rats, similar changes in urinary ammonia excretion were observed without changes in arterial pH, excluding an effect of anesthesia or pH on the obtained results. These results indicate that the kidney plays an important role in the metabolic adaptation to hyperammonemia during chronic liver insufficiency in the rat.
...
PMID:Metabolic adaptation of the kidney to hyperammonemia during chronic liver insufficiency in the rat. 840 65

A 3-month-old llama with a presenting complaint of lethargy, anorexia, and a painful, distended abdomen was evaluated. The llama had intermittently strained to defecate during the 3 days prior to admission. Physical examination results, hematologic data and lateral abdominal radiographs were used to diagnose a large umbilical abscess, which was causing a partial obstruction of the gastrointestinal tract. Under general anesthesia, 3 liters of purulent exudate were drained from the abscess. The abscess cavity was then lavaged with saline solution and its capsule was marsupialized to the skin. Cultures of the abscess content yielded Proteus sp, Streptococcus equisimilis, and Clostridium septicum. Two days after surgery, the llama was drinking, eating, and passing feces. The abscess was lavaged daily for a total of 11 days. Six months after surgery, the llama was the same size as other llamas of the same age, and the owners were pleased with the cosmetic appearance of the ventral abdomen. Umbilical abscesses can vary in size and clinical presentation; they should be recognized as a possible cause of abdominal pain with a potential for causing intestinal obstruction in llamas.
...
PMID:Abdominal pain associated with an umbilical abscess in a llama. 841 58

In 1977 it was reported that chloral hydrate could cause adynamic ileus in rats, leading to morbidity and death. The symptoms were a swollen abdomen, lethargy and anorexia. However, chloral hydrate is still used as an anaesthetic, particularly in Equithesin mixture. We report that Equithesin without chloral hydrate is an effective anaesthetic, with a slightly reduced potency compared to Equithesin itself, and anaesthesia may be maintained for several hours by supplemental doses.
...
PMID:Equithesin without chloral hydrate as an anaesthetic for rats. 874 54


<< Previous 1 2 3 4 5 6 7 Next >>