Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C0278080 (
physical dependence
)
1,658
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
The lifelong nature of panic disorder and the development of effective new treatments have focused attention on long-term use of antipanic medications, particularly benzodiazepines and their possibly addictive nature. Benzodiazepines are generally safe and effective. An understanding of the distinction between chemical dependence and
physical dependence
places problems involved in the use and discontinuation of benzodiazepines into perspective. Patients with a
dual diagnosis
of panic disorder and chemical dependence are at risk of addiction. Others may develop
physical dependence
but are able to discontinue benzodiazepine treatment when panic symptoms subside. The approach to benzodiazepine use and discontinuation should be different for patients with chemical dependence as opposed to patients with
physical dependence
. A four-step approach to discontinuation that is applicable to both groups is offered.
...
PMID:Thinking about stopping treatment for panic disorder. 225 76
