Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0277787 (stigma)
 13,352 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Hospices, unheard of in this country a few years ago, have become a fast-growing American phenomenon. They promise effective pain relief for terminal cancer patients as well as a warm, homey atmosphere where fear and loneliness are minimized. Hospices are basically a creation of the British and it is still unclear how--or even whether--the principles they embody can be successfully incorporated into American medicine. However, hospices can make an important philosophical contribution by showing the way toward removing the stigma attached to death. Hospice principles also have implications for all of health care, in emphasizing the importance of treating the whole person rather than just the disease.
Ann Am Acad Pol Soc Sci 1980 Jan
PMID:The hospice movement and its implications. 1024 68

There is little information on the efficacy of various surgical interventions in terms of health-related quality of life in Parkinson's disease (PD) patients. Most studies evaluated only motor symptoms of PD after surgical treatment avoiding subjective patient's assessment. The goal of this study is the assessment of surgical treatment of PD on quality of life using Parkinson's Disease Questionnaire (PDQ-39). To 134 patients PDQ-39 questionnaires were send, 91 of them responded. Among 91 patients 32 underwent unilateral thalamotomy, 38 unilateral pallidotomy and 21 bilateral staged pallidotomy. The patients were assessed at baseline and 3 to 6 months after surgery. The PDQ-39 recorded significant improvement in mobility, activity of daily living and stigma in thalamotomy and pallidotomy group. The most striking improvement was noticed in bilateral pallidotomy group. After bilateral pallidotomy improvement was noticed in mobility, ADL, emotional well being, stigma and bodily discomfort. Our results indicate that quality of life in PD patients after surgical treatment is measurable according to PDQ-39 and the most benefit is noted in patients who underwent bilateral staged pallidotomy.
Neurol Neurochir Pol 2003
PMID:[Evaluation of quality of life in Parkinson disease treatment]. 1509 50

PR-10 proteins (pathogensis-related), ubiquitous within the plant kingdom, are usually encoded by multigene families. To date we have identified 10 homologous pr-10 genes in a yellow lupine cDNA library. Here, the structure and expression of two newly identified yellow lupine pr-10 genes (LlYpr10-2b and LlYpr10-2f) are presented. Many potential regulatory sites were found in both gene promoters including common ones as well as those unique for each gene. However, promoter deletion analysis in transgenic tobacco plants revealed similar patterns of reporter gene (gus) expression. Shortened fragments of both gene promoters studied caused high GUS activity in leaves (along vascular bundles), stamen stigma, anthers and pollen grains. When conjugated with longer LlYpr-10.2 promoter fragments, GUS was additionally present in petal edges. Only a long fragment of the LlYpr10-2b gene promoter caused GUS expression in the stem. In yellow lupine the pr-10.2 genes are present in all studied organs, but their level of expression depends on the stage of development and is affected by wounding, oxidative stress and salicylic acid treatment. Silencing of the Llpr-10.2b gene in 4-week-old yellow lupine plants did not lead to any visible symptoms, which suggests that the function of the silenced gene is supplemented by its close homologues, still present in the studied plants.
Acta Biochim Pol 2007
PMID:Structural and functional characteristics of two novel members of pathogensis-related multigene family of class 10 from yellow lupine+. 1808 22

Stigmatization is a common problem to overcome for people suffering from chronic diseases. It usually follows infectious diseases, disabilities and mental disorders. In our study we explained basic concepts concerning stigma, particularly health-related one, and then we presented the most important socio-demographic factors influencing attitudes towards mentally ill people exemplifying them by scientific literature on mental illness stigma. Profession, frequency of contact with mentally ill persons, level of mental health literacy, own experience, education level, culture-related factors, overall value orientation, gender and age are the most relevant factors which influence perception of people suffering from mental disorders. A review of surveys on dependencies between those factors and attitudes towards mentally ill people and tendencies to stigmatize with mental illness was presented. Mental health literacy is the most easily modifiable factor among all the presented here. Majority of campaigns concerning change of attitude towards mentally ill people consist in enhancement of mental health awareness in society.
Pol Merkur Lekarski 2009 Mar
PMID:[Stigma and related factors basing on mental illness stigma]. 1938 46

The stereotypes and sigma associated with mental disorders are frequently the main obstacles preventing early and successful treatment. Particularly in the case of schizophrenia, the burden of stigma often leads to chronic social impairment. In the paper, the prevalence of different public beliefs about mental disorders and varied components of the stereotypes of schizophrenia among respondents living in a few European countries (Poland, Switzerland, Germany, Croatia and Spain) are presented. The data have indicated that patients suffering from schizophrenia and their families not rarely have experienced social distancing, exclusion and rejection not only from the general public but also from mental health professionals. In general, respondents are fearful of people diagnosed with schizophrenia and desire emotional distance from them. The public attitudes tend to characterize people suffering from schizophrenia as dangerous, unpredictable, unreliable and so on. The article describes chosen psychological mechanisms that are associated with the presented results and explain the stigma attitudes of respondents.
Psychiatr Pol
PMID:[Stigma and discrimination towards people with schizophrenia--a survey of studies and psychological mechanisms]. 2020 78

The aim of this study is to draw attention to the ambiguity of the relationship between the process of recovery and implemented psychiatric treatment. With getting the diagnosis, a mentally ill person is automatically assigned to a certain society group and is involved into the mental health care system. People with a diagnosis of serious mental illness have to face not only their new health condition and adapt to the available health care system, but also to deal with the reaction of their environment. The process of recovery in mental illness includes remission of symptoms, getting back to the normal functioning, recuperating the life satisfaction, but also means the personal transformation and opposition to stigma. The most of the public demonstrates the stigmatizing opinions and discriminatory behavior in relation to the mentally ill, which does not foster their recovery and social reintegration. The nearest surrounding of the mentally ill is dominated by psychiatric staff, other mentally ill, psychotropic drugs and psychiatric hospital. These factors directly linked to the diagnosis and treatment of a psychiatric patient are supposed to help in recovery. In fact, at the same time they may contribute to recovery, and be a source of additional suffering or impede recovery. Despite symptomatic and functional remission, the mentally ill people stay outside the mainstream, remain socially isolated and excluded.
Psychiatr Pol
PMID:[Stigmatization on the way to recovery in mental illness--the factors directly linked to psychiatric therapy]. 2500 34

Levels of Fe, Mn, Cu, Zn, Mo, Co, Ni, Se, Sn and Al were determined in 14 medicinal plants from Serbia, which are widely used in phytopharmacy as herbal teas. The following plants were investigated: yarrow (Achillea millefolium L.), basil (Ocimum hasilicum L.), St. John's wort (Hypericum perforatum L.), peppermint (Mentha x piperita L.), field horsetail (Equisetum arvense L.), stinging nettle (Urtica dioica L.), thyme (Thymus serpyllum L.), maize silk (Zea mays L. - Maydis stigma), hibiscus (Hibiscus sabdariffa L.), marshmallow (Althaea officinalis L.), chamomile (Matricaria chamomilla L.), rosehip/dog rose (Rosa canina L.), winter savory (Satureja montana L.) and spearmint (Mentha spicata L.). A total of 16 samples of different parts of medicinal plants (root, leaf, flower, herba) were examined, whereby 13 samples were delivered in original package and three samples were loose leaf herbs. Samples were prepared using the microwave digestion technique, and measurements were performed applying the atomic absorption spectrometry and mass spectrometry with inductively coupled plasma. Contents of microelements in the examined samples were in the range: Mn (23.86 - 453.71 mg/kg); Fe (61.87 - 673.0 mg/kg); Cu (6.68 - 24.46 mg/kg); Zn (16.11 - 113.81 mg/kg); Mo (0.576 - 4.265 mg/kg); Co (0.039 - 0.532 mg/kg); Se (0.036 - 0.146 mg/kg); Ni (0.738 - 6.034 mg/kg); Al (154.0 - 3015.0 mg/kg) and Sn (2.68 - 10.22 mg/kg). According to determined amounts of microelements, the investigated samples of herbal teas are considered safe for human consumption.
Acta Pol Pharm
PMID:Levels of some microelements and essential heavy metals in herbal teas in Serbia. 2526 17

Cambodia had suffered enormously due to war and internecine conflict during the latter half of the twentieth century, more so during the Vietnam War. Total collapse of education and health systems during the Pol Pot era continues to be a challenge for developing the necessary infrastructure and human resources to provide basic minimum mental health care which is compounded by the prevailing cultural belief and stigma over mental, neurological and substance abuse disorders (MNSDs). The mental health research and services in Cambodia had been predominantly 'trauma focused', a legacy of war, and there is a need to move toward epidemiologically sound public health oriented mental health policy and service development. Integrating mental health program with primary health care services with specifically stated minimum package of activities at primary level and complementary package of activities at secondary level is an opportunity to meet the needs and rights of persons with mental, neurological and substance abuse disorders (PWMNSDs) in Cambodia, provided there is mental health leadership, government commitment and political will.
...
PMID:Mental health services in Cambodia, challenges and opportunities in a post-conflict setting. 2556 73

Persons with mental disorders often experience stigmatization. There is a number of social factors that may affect the process of recovery and at the same time, in certain circumstances, could be a source of stigma. Mentally ill may find strength in themselves to fight against the disease or the opposite - can internalize the negative attitudes of the society and become self-stigmatized. The patient's family, on the one hand, is often the only source of social support, on the other hand, can experience a destructive influence of courtesy-stigma. Mentally ill have to face social reluctance which is reinforced by stereotypical media coverage of mental disorders. The social network of patients is poor and often limited to a family system. Negative views about persons diagnosed with mental illness are most visible in the labour market. Patients experience many types of discrimination at work,have lower employment rates and lower mean wages than healthy ones. Structural discrimination is a form of stigma which is revealed in underfunded and inefficient system of mental health care. All the social factors mentioned above are necessary for recovery (positive stimulation of functioning), but can also increase stigma and become a significant barrier in the recovery of psychiatric patients. This paper highlights the complex and ambiguous nature of the relationship between social factors and the recovery of the mentally ill basing on the data from the literature.
Psychiatr Pol
PMID:[Stigmatization on the way to recovery in mental illness - the factors associated with social functioning]. 2571 89

The paper presents the CAMILLE training package prepared in the EU program Empowerment of Children and Adolescents of Mentally Ill Parents through Training of Professionals working with children and adolescents. The training is designed for psychiatrists, psychologists, social workers, teachers and others working with children and adolescents where a parent experiences mental disorders. The project was realized on 4 stages: (1) pre-analyses (quality and quantity) with professionals, family members and people experiencing mental disorders, in regards to the needs, experiences and expectations in education of professionals working with families of parents with mental illness; (2) development of a new pan-European training program for specialists working with these families; (3) pre-pilot implementation and evaluation of the training; (4) preparing of the final version of the training and pilot implementation in 7 countries participating in the project, also in Poland. The training program consists of 9 subjects, divided into 3 main groups: the basic knowledge (mental disorders, child development, attachment), experiences and needs of the families (experiences of parents, children, stigma), methods of family support (talking with children, resilience, successful services). The pilot implementation of the program showed great professionals' interest in the subject and training methods. The evaluation showed significant positive effects of the training in terms of the raise of awareness of influence of the parent's illness on needs of the child, parental abilities and ability of building the child resilience. The CAMILLE training is a valuable program that can be implemented in Poland.
Psychiatr Pol 2016
PMID:Empowering families with the experience of mental illness. A presentation of the Polish version of CAMILLE training package. 2784 35


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