Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0277787 (stigma)
 13,352 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Most of the available appetite-suppressant drugs act on noradrenergic and possibly dopaminergic receptors to produce satiety. A smaller number increase excess neuronal serotonin levels by blocking serotonin reuptake or by increasing its release. All these drugs produce significantly greater weight loss than does placebo in most studies. Abuse is a problem with amphetamine, methamphetamine, and benzphetamine, whereas other drugs have minimal or no potential for abuse. Weight loss can be sustained for up to 36 months. Net weight loss, compared with placebo, ranges from 2 to 10 kg, and weight regain after terminating drug treatment proves that drugs do not work when not taken. The stigma of obesity, the public opprobrium toward obese persons, and regulatory rigidity have led to unjustified distrust in the potential of drug treatment for obesity.
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PMID:Use and abuse of appetite-suppressant drugs in the treatment of obesity. 836 2

MFBF was not superior to patching as far as efficacy is concerned in anisometropic amblyopia. However, the combination of more game options to sustain interest, a shorter duration of therapy over the course of a week and software directed compliance monitoring system favors the Amb I Net system from both patient and parental perspective. Amb I Net also negated discomfort, social stigma, and parental monitoring needed with patching regimens. It can be considered as a good alternative to patching in reluctant/non - compliant children with anisometropic amblyopia. This is the first large cohort study based on this therapy.
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PMID:Effect of monocular fixation in binocular field (MFBF) on amblyopia - a pilot study comparing it with patching. 3287 66