Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
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Drug
Enzyme
Compound
Query: UMLS:C0277787 (
stigma
)
13,352
document(s) hit in 31,850,051 MEDLINE articles (0.02 seconds)
We isolated lap3-1 and lap3-2 mutants in a screen for pollen that displays abnormal
stigma
binding. Unlike wild-type pollen, lap3-1 and lap3-2 pollen exine is thinner, weaker, and is missing some connections between their roof-like tectum structures. We describe the mapping and identification of
LAP3
as a novel gene that contains a repetitive motif found in beta-propeller enzymes. Insertion mutations in
LAP3
lead to male sterility. To investigate possible roles for
LAP3
in pollen development, we assayed the metabolite profile of anther tissues containing developing pollen grains and found that the lap3-2 defect leads to a broad range of metabolic changes. The largest changes were seen in levels of a straight-chain hydrocarbon nonacosane and in naringenin chalcone, an obligate compound in the flavonoid biosynthesis pathway.
...
PMID:LAP3, a novel plant protein required for pollen development, is essential for proper exine formation. 2003 37