Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0271276 (Hudson)
 1,066 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

The eyes of 98 long-term contact lens wearers and 342 subjects not wearing contact lenses were examined for the presence of Hudson-Stahli lines, using slit-lamp biomicroscopy. The period of contact lens wear ranged from 2 to 25 years, all subjects using contact lenses for refractive reasons only. The incidence of Hudson-Stahli lines in contact lens wearers was not significantly different from that of control subjects in the same decades. Contact lenses appear, however, variably to alter the characteristics of the Hudson-Stahli line. Results from a group of 4 unilateral lens wearers, from 94 bilateral lens wearers and from studies of the morphology of the line suggest that contact lens wear is associated with a relative reduction of length and density of the line and also with a broadening and, more rarely, displacement of it. In eyes with brown or green irides, the attenuation of length and density by contact lens wear obscures the normal increases seen with age; in this subgroup of contact lens wearers, both factors appear to be almost constant from the third to sixth decades of life.
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PMID:The Hudson-Stahli line. II: A comparison of properties in eyes with and without long-term contact lens wear. 344

Observations as to the morphology, position and orientation of the Hudson-Stahli line are presented, based on the slit-lamp biomicroscopic examination of the eyes of six hundred and forty-four subjects. The origin of the pigments in the Hudson-Stahli zone and other corneal epithelial lines is reviewed, the evidence for either tear film dynamics or epithelial dynamics influencing the typical configuration is discussed and a unified theory for the formation of corneal iron lines is presented.
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PMID:The Hudson-Stahli line. III: Observations on morphology, a critical review of aetiology and a unified theory for the formation of iron lines of the corneal epithelium. 344 1