Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0268596 (EMA)
 2,520 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

The clinico-pathologic, immunohistochemical and radiological features of 12 jaw cysts with a prominent orthokeratinized epithelial lining were studied and compared with those of typical odontogenic keratocysts and dentigerous cysts. They differed significantly from odontogenic keratocysts in terms of biologic behavior and histopathologic findings. Although immunohistochemical staining of the epithelial linings for cytokeratins, EMA, CEA and involucrin has not shed any light on the histogenesis of these lesions, staining patterns for these markers were significantly different from those of odontogenic keratocysts and non-keratinized dentigerous cysts. Radiologically, nine cases appeared as dentigerous cysts; two cases, one with sebaceous differentiation, as non-dentigerous unilocular cysts, and the remaining one was exceptional as it showed multiple epidermal cysts with prominent dermal appendages histologically. It is suggested that most of the orthokeratinized jaw cysts may belong to clinico-pathological entities different from odontogenic keratocysts with the majority representing dentigerous cysts with orthokeratinization. The possibility of the existence of rare central dermoid or epidermoid cysts is also to be considered.
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PMID:Jaw cysts with orthokeratinization: analysis of 12 cases. 767 96

Immunoreactivity with monoclonal antibodies against epithelial membrane antigen, vimentin, keratin-squamous epithelium, keratin-nonsquamous epithelium and with polyclonal antibodies against keratin, involucrin, S-100 protein, desmin and varies; is directly proportional to-1 antitrypsin was done in 30 pleural and peritoneal effusion fluids; 15 each of benign and malignant origin using the avidin-biotin-peroxidase complex (ABC) technique to differentiate between the mesothelial cells and the adenocarcinoma cells. In the present study we have demonstrated that desmin and S-100 protein are distributed in the cancer cells and the mesothelial cells of the effusion fluids. Neither EMA nor keratin has the specific reactive pattern which could lead to the differentiation of the mesothelial cells from the cancer cells, but vimentin and keratin could be used for the diagnosis of the mesothelial cells since they had maximum reactivities compared to the cancer cells.
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PMID:Role of immunoperoxidase staining in serous effusions. 816 32