Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0268596 (EMA)
 2,520 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Ten cases of adenocarcinoma of the endometrium were studied using histochemical methods for mucopolysaccharides and immunocytochemical methods for the localization of various markers, such as EMA (epithelial membrane antigen), GCDFP-15 (gross cystic disease fluid protein) and CEA. Four cases appeared to contain High Iron Diamine-positive substance and 6 cases were positive using an immunocytochemical method with a polyclonal anti-CEA antiserum. In contrast, no cases stained when a monoclonal anti-CEA antiserum was employed. This suggested that HID- positive material could be a sign of differentiation towards cells with a secretory function.
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PMID:Morphofunctional findings in adenocarcinoma of endometrium. 620 31

In this paper are presented the results of immunohistochemical study of 52 cardiac myxomas, including 2 with glandular structures, and the histogenesis of cardiac myxoma is discussed. Immunohistochemical studies revealed that in all these cases, myxoma cells were positive for vimentin and negative for factor VIII, desmin and actin. In 5 cases, myxoma cells were positive for S-100 protein. The 2 cases with glandular structure were positive for CEA, EMA and Cytokeratin. Histochemical staining showed that PAS AB (pH 1.0), PAS AB (pH 2.5) and HID AB were positive with the glandular elements. The results suggest that cardiac myxomas may be derived from "embryonal rests" and that the glandular structure may originate from entrapped primitive gut rests.
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PMID:[Immunohistochemical study and evaluation of histogenesis of cardiac myxoma]. 816 89