Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0268318 (ICP)
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Human Gene/Protein
ICP 11.6
AES 11.3
guanylate binding protein 4 10.6
hHUS1 9.6
helicase II 9.3
AAS 8.7
RCN3 8.6
SALF 8.5
PACS-2 8.4
Selenoprotein M 8.3
BOD1 8.3
SRM 8.3
MT1JP 8.1
ATP1B3 7.9
COPT2 7.9
RAD1 protein 7.9
HGN 7.7
PIGS 7.7
multidrug resistance protein 3 7.6
SARM 7.6
IFI30 7.5
WS-3 7.5
NBL1 7.5
BEAN 7.5
AF4 7.5
HSPE1 7.4
MMA 7.3
HLC-1 7.3
LI2 7.3
COPT1 7.3
C-TAK1 7.3
single strand DNA-binding protein 7.2
ABCB4 7.2
MASK 7.2
arsenic (+3 oxidation state) methyltransferase 7.2
glutathione S-transferase omega 1 7.2
DMA 7.2
Interferon-induced transmembrane protein 3 7.1
MT1F 7.1
MDR3 7.1
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Disease
ICP 11.6
JMS 10.1
Non-ischemic cardiomyopathy 9.3
AAS 8.6
CASS 8.5
hyperthyroid heart disease 8.5
Klebsiella meningitis 7.8
LI2 7.7
MMA 7.3
Acute fatty liver of pregnancy 7.0
Pruritic urticarial papules and plaques of pregnancy 7.0
Manganese deficiency 6.8
PFIC1 6.8
traumatic coma 6.7
Intrahepatic cholestasis 6.6
LADD 6.5
Metallosis 6.5
Pilomyxoid astrocytoma 6.5
DMS 6.5
CHN 6.5
Benign recurrent intrahepatic cholestasis 6.4
AAT2 6.3
optic disc atrophy 6.2
SCP 6.1
Effects of heat 6.1
BLL 6.0
pseudopapilledema 5.9
Enterovirus infection 5.8
TCD 5.8
TEM 5.8
Endemic goiter 5.7
Pseudotumor cerebri 5.7
myelinopathy 5.7
TEM 5.7
Vernet 5.6
FGS 5.5
raised intracranial pressure 5.5
Secondary lymphedema 5.4
ANM 5.4
neurological infection 5.4
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Symptom
Lower extremity weakness 8.6
Induced hypothermia 5.9
Overlying 5.2
Crushing 4.7
photopsia 4.6
hyperemesis gravidarum 4.5
Burning 4.4
HSA 4.3
sinus pressure 4.2
acidity 4.0
hypocapnia 3.9
dark urine 3.5
autodigestion 3.3
No adverse effect 3.3
Hudson 3.2
Spots 2.8
hypothermia 2.6
abdominal cramps 2.6
Fluctuation 2.4
right upper quadrant pain 2.2
blurred vision 2.2
tremor 2.1
hypercapnia 1.9
neurological disability 1.8
DNA marker 1.8
agitation 1.7
Postoperative pain 1.6
catatonia 1.5
rhinorrhea 1.5
tingling 1.3
tonic-clonic seizure 1.3
nasal discharge 1.2
Neuropathic pain 1.2
spasm 1.1
physical appearance 1.1
enuresis 1.0
tinnitus 0.9
exhaustion 0.9
incoordination 0.8
respiratory distress 0.5
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Drug
Sprodiamide 10.1
Aluminum silicate 9.3
Gadobenate dimeglumine 8.5
Bv2 8.2
Omniscan 8.1
Longgu 7.8
Tocopherol acetate 7.8
CCl2F2 7.7
Ferric oxide 7.6
Omniscan 7.5
OptiMARK 7.5
NYS 7.4
Gd-BOPTA 7.2
Ferrlecit 7.1
Calcium citrate 7.1
Mangafodipir trisodium 7.1
Motexafin gadolinium 6.9
DMAA 6.8
Nimotop 6.7
Tryptophane 6.6
EVM 6.5
LCBF 6.4
Magnevist 6.3
Temodal 6.1
Synthroid 6.0
Xanthium 5.9
Hydrotalcite 5.9
Pancreatin 5.8
Folic Acid 5.7
Gadoteridol 5.7
Tiopronin 5.5
Saha 5.5
PFA 5.4
ROX 5.4
Wine 5.3
Lead acetate 5.3
Synthroid 5.2
Lanthanum carbonate 5.1
APM 5.1
Zinc sulfate 5.1
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Enzyme
MMA(V) reductase 9.6
MT 1 7.4
hydroxyquinol 1,2-dioxygenase 7.2
acylcarnitine hydrolase 7.2
GBH 6.4
SCP 6.1
GTP cyclohydrolase II 5.9
nicotianamine synthase 5.8
organomercurial lyase 5.5
DTA 5.0
1-aminocyclopropane-1-carboxylate deaminase 4.8
mercuric reductase 4.7
alliinase 4.7
BMA 4.6
tRNase Z 4.6
MAP 4.5
protocatechuate 3,4-dioxygenase 4.5
cysteine synthase 4.3
APS reductase 4.3
phytochelatin synthase 4.2
PDO 4.2
cysteine dioxygenase 3.8
oxalate oxidase 3.8
prolidase 3.7
focal adhesion kinase 3.7
bilirubin oxidase 3.6
ceruloplasmin 3.5
dihydroorotase 3.5
LIS 3.4
dimethylarginine dimethylaminohydrolase 3.4
ascorbate peroxidase 3.3
granule-bound starch synthase 3.3
NAT 3.3
enterokinase 3.2
ATP sulfurylase 3.2
MAT 3.1
alpha-L-iduronidase 3.1
SNO 3.1
PMT 3.0
phospholipase A1 3.0
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Compound
ELOXATIN 11.6
6-methylphenanthridine 11.6
4-ethyl-2,6,7-trioxa-1-phosphabicyclo[2.2.2]octane 11.6
1-Palmitoylglycerol 11.6
2-pyridinesulfonic acid 11.6
4-methylphenylboronic acid 10.6
5-(1,2-dithiolan-3-yl)pentanamide 10.6
2-propylpiperidine 10.6
o-Arsanilic acid 10.1
Cajanol 9.6
Coproporphyrin I 9.3
Coproporphyrin I 9.3
CDEC 9.3
Coproporphyrin I 9.3
Coproporphyrin I 9.3
C8H9NO3 9.3
Coproporphyrin I 9.3
CDEC 9.3
Dibenzothiophene sulfone 9.3
methaneseleninic acid 9.1
C20H24O6 9.1
methylarsonic acid 8.9
3-amino-4-hydroxyphenylarsonic acid 8.8
hexylphosphonic acid 8.8
hexylphosphonic acid 8.8
hexylphosphonic acid 8.8
methaneseleninic acid 8.8
Se-methylselenocysteine 8.7
dimethylarsinic acid 8.7
dimethylarsinic acid 8.7
dimethylarsinic acid 8.7
dimethylarsinic acid 8.7
dimethylarsinic acid 8.7
HgI4 8.6
Elatine 8.6
THQ 8.6
THQ 8.6
dimethylarsinic acid 8.5
Acid Violet 7 8.5
Dimethylglyoxime 8.5
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