Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0268318 (ICP)
 10,007 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Changes of ICP and CVP during different elevated positionings of the upper part of the body, rotation of the head, and compression of the jugular veins were investigated in 21 patients. Upward positioning leads to ICP-decrease and slight increase of CVP, whereas head rotation and jugular vein compression lead to increased ICP, the CVP remaining almost constant. The pressure changes in the model are equivalent to those in the patients. Therefore it can be assumed that the ICP changes according to positioning are mainly physical phenomena. The conclusion in clinical use: Slight upward positioning with straight head position is optimal in head injured patients.
 ...
PMID:[Clinical and experimental investigations concerning to positoning of head injured patients (author's transl)]. 52 42

A total of 55 polygraphic recording (ICP, EEG, EMG, EOG, Respiration, and ECG) were made in 20 comatose patients following cranial injuries, during the week after the injury. Whenever the ICP was stable, and without waves, and whatever the mean values were, the EEG tracing was slow, monomorphic, of large amplitude, and nonreactive. Each time that ICP recordings included Lundberg's B waves, the EEG tracings showed alternating bursts of slow waves and periods of rapid activity, with or without typical sleep patterns. The ICP increases each time there is flattening of the tracing and diminishes with the reappearance (spontaneous or provoked) of slow waves. The artificial respiration is not always involved in determining these phenomena.
 ...
PMID:[Correlations between intracranial pressure (I.C.P.) and EEG changes during traumatic coma (author's transl)]. 53 23

Polygraphic studies were performed over periods of 14 to 76 hours in 30 patients with reccent closed cranial injuries. Correlations between ICP and EEG findings were rarely found (3/16) in cases of cerebral dysfunction of mesodiencephalic or lower levels, where both ICP and EEG were usually stable. Correlations are regularly found in diencephalic or higher (10/14) levels and their presence is of favourable prognostic significance. Generally, delta waves at 1,5-2 cs, high in amplitude (type A) accompany reduced or low ICP levels,while a rapid and low voltage tracing (type B) is associated with raised or high levels of ICP. In the latter cases, a very slow (0.5 cs) and low in amplitude tracing (type C) can progressively replace the type B. The classical periodic or alternating tracing associates alternate sequences of type A and B and is observed simultaneously with type B pressure waves. These correlations are analogous with those observed during the evolution of intracranial tumors or hydrocephalus. The EEG modifications are probably related more to the pathological lesion than to a direct action of fluctuations in ICP.
 ...
PMID:[Correlations between intracranial pressure variations and EEG changes in patients with cranial trauma (author's transl)]. 53 24

An ICP-monitoring device utilizing an extradural method is described. Clinical and laboratory use has shown it to be easily installed, safe, accurate, and reliable. It can be used with currently available transducers and monitoring equipment. It is hoped that this simple device will encourage the increased use of ICP monitoring.
 ...
PMID:Device for extradural monitoring of intracranial pressure: technical note. 53 78

In 18 cases of perinatal intraventricular haemorrhage, continuous ventricular drainage was applied. As a result, ICP hypertension was inhibited and thus brain damage prevented. The early intervention prevented the formation of hydrocephalus (evoidence of shunt dependence) and aspiration of the bleeding prevented DIC and maintained coagulation factors.
 ...
PMID:Successful treatment of perinatal intraventricular haemorrhage. 54 18

On the basis of a series of 75 patients, the practical use of Icp continuous long-term recording in severe head injuries without mass lesions or remaining deeply comatose after surgical procedures is critically analyzed. ICP monitoring alone seems to be not essential for prognosis. Conversely it is of much greater use as a guide to management (respirator treatment, osmotics, CSF drainage). If the pros and cons of the procedure are carefully weighed, it would appear that, for the time being, ICP long-term monitoring is justified only in comatose patients on intensive care.
 ...
PMID:Long-term intracranial pressure monitoring in comatose patients suffering from head injuries. A critical survey. 60 50

In 8 patients having primarily an increased ICP, the effects of etomidate on ICP, arterial pressure and cerebral perfusion pressure (CPP) were studied by comparison with thiopentone. The patients received no premedication or basic anaesthesia and relaxation was obtained using pancuronium bromide. Blood gas analysis was performed at regular intervals to maintain a constant level of the arterial pCO2. Under the conditions of a reduced intracranial compliance and an elevated ICP, thiopentone lowered the arterial pressure considerably in contrast to etomidate. The primarily elevated ICP was reduced by both, etomidate and thiopentone to an extent of 27 per cent for more than 10 min. The considerable decrease of arterial pressure by thiopentone caused marked lowering of CPP during more than 10 min. In the same period etomidate did not influence either arterial pressure or CPP. These results show that for the induction of anaesthesia in neurosurgical patients having a primarily increased ICP etomidate has good properties.
 ...
PMID:[Effects of etomidate and thiopentone on the primarily elevated intracranial pressure (ICP) (author's transl)]. 63 95

Thirty-five patients with meningiomas were compared with 37 patients with astrocytomas with respect to the postoperative course of their ICP and elastance. In the case of the meningioma patients, the ICP increased on average over a longer period and achieved higher values than in the astrocytoma patients. In the first group, the elastance attained values that were three times as high as in the second group. There was no fixed relationship between pressure and elastance in the two groups of patients.
 ...
PMID:The course of intracranial pressure and volume-pressure relationships following extirpation of meningiomas and astrocytomas. 74 21

If good anesthesia is to be provided to the patient undergoing surgery for an expanding intracranial lesion, certain principles should be borne in mind. These principles include: 1. Careful preoperative assessment of the patient 2. Awareness of abnormal intracranial dynamics in the presence of an intracranial mass lesion 3. The importance of a smooth induction of anesthesia 4. Adequate depth of anesthesia and complete muscle paralysis before laryngoscopy and intubation 5. The choice of a maintenance technique that does not increase ICP and allows adequate CPP. Failure to adhere to these principles may lead to sudden increases in intracranial pressure, decreased cerebral perfusion pressure, and regional ischemia. In the closed skull, internal herniation of brain tissue through the tentorial notch or the foramen magnum may occur. External brain herniation, with increased bleeding and rupture of cerebral cortex, may occur after the dura mater has been opened if these anesthetic parameters are not controlled. Neuroanesthesia, therefore, plays an important role in the reduction of morbidity and mortality in the surgery of intracranial lesions of all types, including neoplasms - not only in the operating room, but also in the pre- and postoperative care of the neurosurgical patient.
 ...
PMID:Anesthesia for intracranial surgery with particular reference to surgery for neoplasms. 77 21

In five baboons and 11 cats cerebral ischaemia was produced either by inflating an epidural balloon and or by ligating major arteries supplying the brain. Fifteen of the animals developed intracranial hypertension after cerebral ischaemia. If ICP were high, but still significantly lower than MABP, elevation of MABP by noradrenaline infusions was accompanied by a proportional increase of ICP. However, the increase of ICP was lower than that of MABP so that CPP was raised. CBF measured by the 133Xenon clearance technique was significantly increased by arterial hypertension in eight cases. The proportional increase of CPP and CBF by elevation of arterial blood pressure was substantially greater, the lower ICP was immediately after ischaemia. There was no effect of MABP in cases in which ICP equalled MABP.
 ...
PMID:Effect of systemic arterial blood pressure on cerebral blood flow in intracranial hypertension. 81 13


<< Previous 1 2 3 4 5 6 7 8 9 10 Next >>