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Query: UMLS:C0268318 (
ICP
)
10,007
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
Roxarsone (3-nitro-4-hydroxyphenylarsonic acid,
ROX
) is an arsenic-containing compound widely used as a feed additive in poultry industries.
ROX
excreted in chicken manure can be transformed by microbes to different arsenic species in the environment. To date, most of the studies on microbial transformation of
ROX
have focused on anaerobic microorganisms. Here, we isolated a pure cultured aerobic
ROX
-transforming bacterial strain, CZ-1, from an arsenic-contaminated paddy soil. On the basis of 16S rRNA gene sequence, strain CZ-1 was classified as a member of the genus Enterobacter. During
ROX
biotransformation by strain CZ-1, five metabolites including arsenate (As[V]), arsenite (As[III]), N-acetyl-4-hydroxy-m-arsanilic acid (N-AHPAA), 3-amino-4-hydroxyphenylarsonic acid (3-AHPAA) and a novel sulfur-containing arsenic species (AsC
9
H
13
N
2
O
6
S) were detected and identified based on high-performance liquid chromatography-inductively coupled plasma mass spectrometry (HPLC-ICP-MS), HPLC-
ICP
-MS/electrospray ionization mass spectrometry (ESI-MS) and HPLC-electrospray ionization hybrid quadrupole time-of-flight mass spectrometry (ESI-qTOF-MS) analyses. N-AHPAA and 3-AHPAA were the main products, and 3-AHPAA could also be transformed to N-AHPAA. Based on the results, we propose a novel
ROX
biotransformation pathway by Enterobacter. sp CZ-1, in which the nitro group of
ROX
is first reduced to amino group (3-AHPAA) and then acetylated to N-AHPAA.
...
PMID:Biotransformation of arsenic-containing roxarsone by an aerobic soil bacterium Enterobacter sp. CZ-1. 3070 81
Ti (IV) modified vinyl phosphate magnetic nanoparticles (Fe
3
O
4
@SiO
2
@KH570-PO
4
-Ti (IV)) was prepared for simultaneous extraction of multiple arsenic species, followed by high performance liquid chromatography (HPLC) - inductively coupled plasma mass spectrometry (ICP-MS) analysis. Inorganic arsenic (iAs), dimethyl arsenic acid (DMA), monomethyl arsenic acid (MMA), p-amino phenyl arsenic acid (p-ASA), 4-hdroxyphenylarsenic acid (4-OH), phenyl arsenic acid (PAA) and 3-nitro-4-hydroxyphenylarsenic acid (
ROX
) were investigated as interest analytes. It was found that they were quantitatively adsorbed on Fe
3
O
4
@SiO
2
@KH570-PO
4
-Ti (IV) at pH 5, and desorbed completely with 0.1 mol/L sodium hydroxide solution. Enrichment factor of 100-fold was obtained by consuming 100 mL sample solution. Under the optimal conditions, the method combining MSPE with HPLC-
ICP
-MS presented a linear range of 1-5000 ng/L for seven arsenic species. The limits of detection were 0.39, 0.60, 0.23, 1.85, 0.54, 0.48 and 0.84 ng/L for DMA, MMA, p-ASA, iAs, 4-OH, PAA,
ROX
, with the relative standard deviations (c = 10 ng/L, n = 7) of 3.6, 3.9, 5.5, 12.4, 6.1, 5.8, 5.0, respectively. The accuracy of the method was validated by analyzing BCR 627 Tuna fish. The application potential of the method was further evaluated by chicken muscle and liver samples. No target arsenic species were detected in these samples, and good recoveries (80.6-123%) were obtained for the spiked samples at low, medium and high concentration levels. This article is protected by copyright. All rights reserved.
...
PMID:Ti (IV) modified vinyl phosphate magnetic nanoparticles for simultaneous preconcentration of multiple arsenic species from chicken samples followed by HPLC-ICP-MS analysis. 3304 65
