Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0268318 (ICP)
 10,007 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

An extremely small amount of several heavy metals have been detected in cosmetic products as impurities, which can cause skin allergies through percutaneous adsorption on the skin. We present here a fast, accurate, and highly sensitive method for simultaneous determination of Pb2+, Fe2+, Cu2+, Ni2+, Zn2+, Co2+, Cd2+ and Mn2+ in coloring agents and cosmetic products, to be evaluated by ion chromatography. All of these metals are well separated through a bifunctional ion-exchange column (IonPac CS5A) and detected by post-column reaction and spectrophotometric detection. The calibration graphs are linear (r2 > 0.999), in the range 0.1-1000 microg/ml. Detection limits for a 200-microl sample solution are at the mug/l level, which is sufficient for judging whether the product is safe or not. The relative standard deviations (RSDs) of the retention time and the peak area are less than 0.21% and 1.24%, respectively. The recovery rates are 97-104%. The result shows that the proposed determination method is more sensitive, more accurate, and faster than current methods such as HPLC, ICP-MS and Flame-AAS. The new method was applied to analyze the amount of heavy metals contained in 22 cosmetic products and 11 coloring agents.
 ...
PMID:Simultaneous determination of heavy metals in cosmetic products. 1884 8

Five kinds of Mongolia medicines, Eridun-Urile, Deduhonghuaqiweiwan, Tonglage-5, Uzhumu-7 and Geiwang-9 are digested with HNO3-HClO4 system by high pressure system-sealed Microwave Digestion. The 17 inorganic elements content of magnesium, aluminum, calcium, chromium, manganese, ferrum, cobalt, nickel, copper, zincum, arsenic, selenium, strontium, molybdenum, silver, cadmium, plumbum in the solution are determined by ICP-AES. The results are proved to be reliable by adding standard recovery experiment. The recovery is 97.48%-103.01% for Mg, 102.71%-105.60% for Al, 102.00%-105.53% for Ca, 98.78%-100.34% for Cr, 101.93%-104.65% for Mn, 100.34%-104.51% for Fe, 103.13%-105.46% for Co, 100.07%-103.22% for Ni, 97.25%-99.06% for Cu, 98.57%-100.10% for Zn, 102.35%-105.37% for As, 100.24%-104.59% for Se, 99.19%-102.70% for Sr, 103.35%-105.78% for Mo, 99.65%-101.32% for Ag, 102.73%-105.32% for Cd, and 104.76%-106.35% for Pb by this method. The relative standard deviation is less than 3.3% for all the elements. And the method has high accuracy and good precision The determination results indicate that the content of element in Five Kinds of Mongolia Medicines is 0-15 microg x g(-1) for Cd, Ag, As, Pb, Co, Ni, Cu; 15-100 microg x g(-1) for Mo, Se, Zn, Cr; 100-3 000 microg x g(-1) for Mn, Sr, Fe, Mg, Al; 3 000-8 000 microg x g(-1) for Ca. Among of the five kinds of mongolia medicines, the content of elements has great differences. The order is Ca > Mg > Al > Fe > Mn > Sr > Se > Zn > Mo > Cu > Pb > As >Cr > Ni > Co > Cd > Ag for Eridun-Urile; Ca > Al > Fe > Mg > Mn > Sr > Se > Mo > Zn > Ni > Cr > Cu > Pb > As > Co > Cd > Ag for Deduhonghuaqiweiwan; Ca > Fe > Mg > Al > Mn > Sr > Se > Zn > Mo > Cr > Ni > Cu > Pb > As > Co > Cd > Ag for Tonglage-5, Ca > Al > Mg > Fe > Sr > Mn > Se > Zn > Co > Mo > Cr > Cu > Pb > As > Ag > Ni > Cd for Uzhumu-7 and Mg > Ca > Al > Fe > Se > Mn > Zn > Sr > Mo > Cu > Cr > Pb >As > Ag > Co = Cd = Ni for Geiwang-9. The content of common elements Ca, Mg, Fe, Mn, Zn, Cu are higher. These results provide theoretical basis for developing quality control, improving the potency of Mongolia medicines and developing new Mongolia medicines.
 ...
PMID:[Determination of inorganic elements in five kinds of Mongolia medicines by high pressure sealed microwave digestion-ICP-AES]. 1884 80

Occupational/environmental exposure to some metallic elements is a risk factor for the development of lung diseases, including lung cancer. We aimed at investigating the levels of arsenic, beryllium, cadmium, cobalt, chromium, nickel and lead in the lung tissue of patients affected by early stage non small cell lung cancer (NSCLC). A small number of patients without a diagnosis of lung cancer were also included as control group. Lung tissue biopsies were collected from 45 NSCLC patients (both cancerous and unaffected tissues) and 8 control subjects undergoing surgery. Patients were stratified for smoking habits, histopathology and cancer sites. Metallic elements were determined in dry tissue after digestion by means of ICP-MS. Cd, Ni and Pb levels were higher in unaffected than in control tissues (0.52 vs 0.18 microg/g dry, p < 0.05 for Cd; 4.49 vs 1.8 microg/g dry,p < 0.05 for Ni; 0.21 vs 0.06 microg/g dry, p < 0.01 for Pb). The three elements, and particularly Cd, were influenced by smoking habits; Pb levels were higher in squamocellular carcinoma than adenocarcinomas; Ni distributed in the lungs in an inhomogeneous way. This study demonstrates that the unaffected lung tissue is more representative than the cancerous tissue of the pulmonary content of metallic elements. Tobacco smoke is a main factor affecting the concentration levels of Cd, Pb, and to a lesser extent Ni in the lung tissues of NSCLC patients. The role of past environmental-occupational exposures could not be fully elucidated, due to the limited sample size and the retrospective nature of the study.
 ...
PMID:Metallic elements in pulmonary biopsies from lung cancer and control subjects. 1892 9

Spark ablation-inductively coupled plasma (SA-ICP) spectrometry is applied to the measurement of hafnium-zirconium ratios in zircons and to the determination of cerium, cobalt, iron, lead, nickel and phosphorus in ferromanganese nodules. Six operating parameters used for the high-voltage spark and argon-ICP combination are established by sequential simplex optimization of both signal-to-background ratio and signal-to-noise ratio. The time-dependences of the atomic emission signals of analytes and matrix elements ablated from a finely pulverized sample embedded in a pressed disk of copper demonstrate selective sampling by the spark. Concentration ratios of hafnium to zirconium in zircons are measured with a precision of 4% (relative standard deviation, RSD). For ferromanganese nodules, spectral measurements based on intensity ratios of analyte line to the Mn(II) 257.610 nm line provide precisions of analysis in the range from 7 to 14% RSD. The accuracy of analysis depends on use of standard additions of the reference material USGS Nod P-1, and an independent measurement of the Mn concentration.
 ...
PMID:Spark ablation-inductively coupled plasma spectrometry for analysis of geologic materials. 1896 4

A system for separation of zinc traces from large amounts of cadmium is proposed in this paper. It is based on the solid-phase extraction of the zinc in the form of thiocyanate complexes by the polyurethane foam. The following parameters were studied: effect of pH and of the thiocyanate concentration on the zinc extraction, shaking time required for quantitative extraction, amount of PU foam necessary for complete extraction, conditions for the separation of zinc from cadmium, influence of other cations and anions on the zinc sorption by PU foam, and required conditions for back extraction of zinc from the PU foam. The results show that zinc traces can be separated from large amounts of cadmium at pH 3.0+/-0.50, with the range of thiocyanate concentration from 0.15 to 0.20 mol l(-1), and the shaking time of 5 min. The back extraction of zinc can be done by shaking it with water for 10 min. Calcium, barium, strontium, magnesium, aluminum, nickel and iron(II) are efficiently separated. Iron(III), copper(II) and cobalt(II) are extracted simultaneously with zinc, but the iron reduction with ascorbic acid and the use of citrate to mask copper(II) and cobalt(II) increase the selectivity of the zinc extraction. The anions nitrate, chloride, sulfate, acetate, thiosulphate, tartarate, oxalate, fluoride, citrate, and carbonate do not affect the zinc extraction. Phosphate and EDTA must be absent. The method proposed was applied to determine zinc in cadmium salts using 4-(2-pyridylazo)-resorcinol (PAR) as a spectrophotometric reagent. The result achieved did not show significant difference in the accuracy and precision (95% confidence level) with those obtained by ICP-AES analysis.
 ...
PMID:Quantitative separation of zinc traces from cadmium matrices by solid-phase extraction with polyurethane foam. 1896 83

Water-soluble heavy metal salts injure health when they leach into water supplies. It is important that students who may later be employed in industries generating aqueous solutions of such salts are aware of the methods that can be used to recover the metal salt or transform it to non-health threatening products. The research was in the management of small quantities of hazardous wastes, such as are generated in school, college, and university teaching laboratories; in research laboratories; in industrial quality control and testing laboratories; and in small industries. Methods for the recovery of silver, nickel, and cobalt salts from relatively small volumes of aqueous solutions of their soluble salts were developed and tested. Where it was not practical to recover the metal salt, the practice has been to convert it to a water-insoluble salt, often the sulfide. This requires the use of highly toxic reagents. It was found that a number of heavy metal salts can be precipitated as the silicates, returning them to the form in which they are found in the natural ore. These salts show similar solubility properties to the sulfides in neutral, acidic, and basic aqueous solutions. The work has determined the conditions, quantities, and solution acidity that result in the most effective precipitation of the heavy metal salt. The concentration of the metal ions remaining in solution was measured by AA and ICP spectrometry. Specific methods have been developed for the conversion of salts of mercury and chromium to nonsoluble products.
 ...
PMID:Protecting health. 1899 43

The concentrations of cadmium, cobalt, chromium, copper, iron, manganese, nickel, lead, and zinc were determined by ICP-AES in muscles and livers of eight fish species sampled from the Aegean and Mediterranean seas of Turkey. Iron showed the highest levels, followed by Zinc in examined tissues of all fish species. Metal concentrations in edible parts of fish species were 0.03-0.37 mg kg(-1) for cadmium, 0.02-0.42 mg kg(-1) for cobalt, 0.15-1.78 mg kg(-1) for chromium, 0.17-1.11 mg kg(-1) for copper, 11.0-33.4 mg kg(-1) for iron, 0.02-0.89 mg kg(-1) for manganese, 0.22-4.03 mg kg(-1) for nickel, 0.22-0.64 mg kg(-1) for lead, and 2.88-10.9 mg kg(-1) for zinc, respectively. All metal concentrations in livers were higher than those in muscles. In some stations, cadmium, chromium, cobalt, and lead concentrations in both muscles and livers of the examined species were higher than permissible safety levels for human uses.
 ...
PMID:Metal concentrations in eight fish species from Aegean and Mediterranean Seas. 1906 6

A simple, sensitive and interference-free method was proposed for the determination of arsenic, based on the generation of volatile arsenic trichloride coupled with atomic fluorescence spectrometry. Thiourea, together with l-ascorbic acid, was used to reduce As(V) to As(III), and the chloride generation was based on the reaction between As(III) and hydrochloric acid. Under the optimized experimental conditions, the present procedure allows for the quantification of arsenic in the concentration range of 0.01-4.0 mg L(-1), with a limit of detection (3sigma) of 6.0 microg L(-1). The relative standard deviation (R.S.D.) is 4.0% for 0.1 mg L(-1) arsenic (n=7). Finally, the proposed method was successfully applied to the determination of arsenic in several certified reference samples (stainless steel, alloy steel, copper alloy and water sample) and real samples (brass material and spiked cobalt material), with analytical results well-agreed with those by ICP-MS.
 ...
PMID:Simple and sensitive determination of arsenic by volatile arsenic trichloride generation atomic fluorescence spectrometry. 1907 24

A method has been developed for the determination of cobalt, copper and manganese in green coffee using direct solid sampling electrothermal atomic absorption spectrometry (SS-ET AAS). The motivation for the study was that only a few elements might be suitable to determine the origin of green coffee so that the multi-element techniques usually applied for this purpose might not be necessary. The three elements have been chosen as test elements as they were found to be significant in previous investigations. A number of botanical certified reference materials (CRM) and pre-analyzed samples of green coffee have been used for method validation, and inductively coupled plasma optical emission spectrometry (ICP OES) after microwave-assisted acid digestion of the samples as reference method. Calibration against aqueous standards could be used for the determination of Mn and Co by SS-ET AAS, but calibration against solid CRM was necessary for the determination of Cu. No significant difference was found between the results obtained with the proposed method and certified or independently determined values. The limits of detection for Mn, Cu and Co were 0.012, 0.006 and 0.004mugg(-1) using SS-ET AAS and 0.015, 0.13 and 0.10mugg(-1) using ICP OES. Seven samples of Brazilian green coffee have been analyzed, and there was no significant difference between the values obtained with SS-ET AAS and ICP OES for Mn and Cu. ICP OES could not be used as a reference method for Co, as essentially all values were below the limit of quantification of this technique.
 ...
PMID:Method development for the determination of manganese, cobalt and copper in green coffee comparing direct solid sampling electrothermal atomic absorption spectrometry and inductively coupled plasma optical emission spectrometry. 1907 13

An advanced inorganic ion exchanger, zirconium titanium phosphate (ZTP) of the class of tetravalent bimetallic acid (TBMA) salt has been synthesized by sol-gel route. ZTP has been characterized for ICP-AES, TGA, FTIR and XRD. Chemical stability of the material in various media-acids, bases and organic solvents has been assessed. Cation exchange capacity (CEC) and effect of calcination (100-500 degrees C) on CEC has also been studied. Distribution behaviour of metal ions Co2+, Ni2+, Cu2+, Zn2+ (d-block), Cd2+, Hg2+, Pb2+, Bi3+ (heavy) and La3+, Ce3+, Th4+, UO(2)2+ (f-block) towards ZTP has been studied and distribution coefficient (K(d)) determined in aqueous as well as various electrolyte media/concentrations. Based on the differential selectivity, breakthrough capacity (BTC) and elution behaviour of various metal ions towards ZTP, a few binary and ternary metal ion separations have been carried out.
 ...
PMID:Synthesis and characterization of zirconium titanium phosphate and its application in separation of metal ions. 1963 44


<< Previous 1 2 3 4 5 6 7 8 9 10 Next >>