Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C0268318 (
ICP
)
10,007
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
Intrahepatic cholestasis of pregnancy
(
ICP
) is a rare disease occurring mainly during the last trimester of pregnancy. Pruritus, often accompanied by excoriation of the skin but without other skin lesions, and elevated concentrations of bile acids are characteristic for this disorder. We present a 30-year-old woman with pruritus, elevated bile acids,
ASAT
and ALAT in the 22nd week of pregnancy. Treatment with ursodeoxycholic acid resulted in complete disappearance of the pruritus and normalisation of the bile acids,
ASAT
and ALAT. A healthy child was born at term. In the differential diagnosis of liver function abnormalities during pregnancy,
ICP
should be included.
ICP
responds very well to treatment with ursodeoxycholic acid, with no detrimental effects for mother and child.
...
PMID:Intrahepatic cholestasis of pregnancy. 1257 4
