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Query: UMLS:C0268318 (ICP)
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Since Lundberg first described slow oscillations as so called B-waves during ICP-monitoring, similar oscillations have been found in various physiological systems. Thus, the detection of slow waves in intracranial CSF- and blood-flow with MR-techniques seemed very likely. We examined the interventricular CSF-flow and cerebral blood flow of 11 healthy volunteers with dynamic echo-planar imaging by simultaneous registration of respiration and peripheral pulse. The spectral analysis was restricted to slow waves, which were divided into B-waves (0.008-0.05 Hz), Mayer- or C-waves (0.05-0.15 Hz) and respiration-related waves (0.15-0.6 Hz). In the CSF, the integrated amplitude of B-waves accounted for 18.2%, Mayer- or C-waves for 26.9% and respiration-related waves for 55.0%. Proportional values were recorded in the artery and peripheral pulse. In the venous sinus, a higher percentage of B- and Mayer-/C-waves and a lower percentage of respiration related waves were found. In conclusion, with MR-EPI technique, slow rhythmic oscillations in the cerebral blood- and CSF-flow can be analysed non-invasively and independently from the cardiac cycle. The comparable distribution of slow waves in the pulse, arteries and CSF may reflect an origin in autoregulation, whereas divergent patterns like in the incompressible venous sinus may be of a passive origin.
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PMID:Slow rhythmic oscillations in intracranial CSF and blood flow: registered by MRI. 1216 86