Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0268140 (XPF)
549 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
XPF 519
ERCC1 315
endonuclease 175
XPG 136
XPA 116
XPC 97
XPD 72
Mol 71
ERCC4 44
XPB 39
TFIIH 39
Sep 39
MUS81 35
helicase 32
RPA 31
EME1 23
NER 23
XRCC3 21
ERCC1 protein 18
proliferating cell nuclear antigen 17
FANCD2 16
TRF2 16
BRCA1 16
XRCC1 16
p53 15
CSB 15
CPF 13
BLM 12
HR23B 12
BRCA2 12
MSH2 11
ERCC5 11
telomeric 11
ERCC2 11
histone 10
ATM 10
XPE 10
ATR 9
RAD51 9
XRCC2 9
DNA polymerase 9
FANCM 9
ATP 8
ubiquitin 8
H2AX 8
trichothiodystrophy 8
DDB2 8
DNA repair endonuclease XPF 7
NMR 7
ubiquitin ligase 7
NBS1 7
excision repair cross-complementing 1 7
MLH1 6
ERCC6 6
hHR23B 6
OGG1 6
FANCA 6
topoisomerase I 6
excision repair protein 6
WRN 5
APE1 5
proteasome 5
EXO1 5
PARP1 5
XPV 5
MSH3 5
ERCC3 5
SOD 5
Fanconi anemia protein 4
cancer susceptibility 4
Chk1 4
Pol 4
tyrosyl-DNA phosphodiesterase 1 4
CSA 4
Gen 4
FANCC 4
cytochrome P450 4
p21 4
DNA helicase 4
ERCC4 protein 4
RNA polymerase II 4
DNA-dependent protein kinase 4
MF1 4
TRF1 4
SNM1A 4
SUMO 4
GSTP1 4
RAD1 4
TOP1 3
DNA polymerase delta 3
NAT2 3
SPO 3
FEN1 3
HN2 3
core protein 3
RAD 3
GSTT1 3
hOGG1 3
MRE11 3
Rad51 3
Ku86 3
DDB1 3
UTR 3
histone H2A 3
ATRIP 3
TDP1 3
BTBD12 3
CYP1A1 3
Werner syndrome 3
Fanconi anemia, complementation group A 3
XRCC5 3
PARP 3
DDP 3
FAAP24 3
DNase I 2
FANCF 2
APC 2
FHIT 2
polypeptide 2
ADP 2
D. melanogaster 2
insulin 2
RAD50 2
PMS2 2
HD1 2
novel gene 2
DCC 2
cryptic 2
DNA ligase I 2
xenobiotic 2
Ku70 2
transcriptional factor 2
E3 ubiquitin ligase 2
TopBP1 2
CYP2E1 2
RFC 2
telomeric repeat binding factor 2 2
HUS1 2
AGT 2
POLQ 2
phosphatase 2
DNA repair enzyme 2
mTOR 2
p34 2
CEP 2
transcription factor TFIIH 2
cyclin D1 2
c-Jun 2
RAD54 2
ATPase 2
POLH 2
CFP 2
promyelocytic leukemia 2
CTCF 2
FANCI 2
POLB 2
MUS81 endonuclease 2
Bloom syndrome 2
AP-1 2
MIC 2
HD2 2
single-stranded DNA-binding protein 2
MEH 2
deoxyribonuclease 2
RPA70 2
general transcription factor 2
TOP3 2
PLK1 2
CHK2 2
CAK 2
UV20 2
fascin 2
ROS 2
CRL4 2
DNA repair protein 2
methylguanine-DNA methyltransferase 2
FANCJ 2
fused 2
ATRX 2
AMP 2
non-catalytic 2
p97 2
poly(ADP-ribose) polymerase 2
hMLH1 2
p70 2
caspase-3 2
RAD23B 2
LIG3 2
HPRT 2
mer 2
pol 2
GSTM1 2
H2A 2
endonuclease III 2
She 1
TAF 1
NQO1 1
Maf 1
hMSH3 1
CYP19 1
CtIP 1
BTR 1
CYP2D6 1
RAD26 1
Proliferating cell nuclear antigen 1
ADH2 1
thymus 1
FOXO3 1
BRCAI 1
MRE11A 1
AlkB 1
SAGE 1
p60 1
AML 1
POLD3 1
SP3 1
TOPBP1 1
HS3 1
Sp1 1
ARTEMIS 1
TESS 1
ATF 1
SMC1A 1
Ku80 1
CD95L 1
FHOD1 1
MI-ER1 1
MLR 1
reductase 1
insulin-like growth factor 1 1
IL6 1
p16 1
SWI 1
ataxin-3 1
UGT1A6 1
RNA helicase family 1
MER3 1
CDK2 1
Wip1 1
p62 1
CASP9 1
calpain 1
SYCP1 1
alpha-spectrin 1
GDX 1
CCK 1
MSH4 1
GATC 1
endoplasmic reticulum 1
TEX11 1
TAF12 1
c-fos 1
TdT 1
A-T 1
CCT 1
glucagon receptor 1
DNA-binding protein 1
hemoglobin 1
CPD 1
Claspin 1
like kinase 1
CENP-E 1
CG6 1
exonuclease 1 1
MSH6 1
GTF2H5 1
zinc finger 1
p56 1
FAS 1
RAD18 1
beta-globin 1
EME2 1
p13 1
hypoxanthine-guanine phosphoribosyltransferase 1
Smad3 1
NEIL1 1
p57 1
DNA-binding domain 1
BARD1 1
MLH3 1
lactate dehydrogenase 1
UBC9 1
glucose transporter 1
PARP-1 1
TERF2IP 1
CD82 1
RAP1 1
USP45 1
RRM1 1
WDR68 1
phosphorylating 1
CYP1B1 1
TBP-associated factor 1
extracellular signal-regulated kinase 1
CAST 1
CUL4 1
aP2 1
Met 1
TMP 1
growth hormone 1
cIAP1 1
dimeric 1
SMC3 1
IAP2 1
1A1 1
MEK 1
zinc finger motif 1
PAH 1
KAT5 1
MRI 1
lipoprotein lipase 1
GCF 1
MutY homolog 1
CDK12 1
DAF 1
Glutathione S-transferase 1
MRP 1
Cdc5 1
Rad50 1
serine/threonine kinase 1
S. cerevisiae) 1
ACT 1
CAF-1 1
AN2 1
ras 1
beta-actin 1
interacting protein 1
C9orf84 1
GSH 1
ARK 1
FANCL 1
RPA2 1
ubiquitin-conjugating enzyme 1
glutathione S-transferase 1
FAN 1
p65 1
osteosarcoma 1
flap endonuclease 1 1
RPA32 1
Kip2 1
telomeric DNA binding protein 1
Barth syndrome 1
UVS 1
interleukin-6 1
putative transcription factor 1
histone H2B 1
DNMT1 1
docking protein 1
DAC 1
cytochrome 1
RAR-beta 1
P34 1
PTEN 1
cyclin E 1
MUTYH 1
NTM 1
TOP 1
MTHFR 1
RANKL 1
AAG 1
Eg5 1
DNA ligase 1 1
Smad2 1
NADPH 1
C-C 1
53BP1 1
tumor necrosis factor 1
TIP60 1
erythroid 1
hMSH2 1
E. coli) 1
histone deacetylase 1
Poly 1
phosphodiesterase 1
SETX 1
ATX 1
oxidoreductase 1
CIP1/WAF1 1
ERCC8 1
CDK7 1
Pseudomonas 1
xeroderma pigmentosum variant 1
testis-specific 1
Mcl-1 1
SSA 1
Nei 1
ataxia telangiectasia mutated 1
Apaf-1 1
GAL4 1
NEIL3 1
ATR-interacting protein 1
14-3-3 sigma 1
p44 1
MRX 1
p52 1
REV3 1
PTD 1
DNMT3A 1
U1A 1
CASP3 1
DUSP6 1
RPA4 1
MOP 1
FISH 1
TLS 1
mismatch repair protein 1
GADD45 1
ALKBH2 1
TCR 1
IL-6 1
RyR1 1
CDC45 1
X-linked 1
transcription factor IIIA 1
Cx43 1
PRP19 1
PNKP 1
SNM1 1
POLD4 1
CASP8 1
regulator of telomere length 1
WDR76 1
Intermedin 1
MCM2 1
PCC 1
SMC 1
MAPK 1
PALB2 1
FANCD1 1
p48 1
vitamin D receptor 1
FANCG 1
CHK1 1
FAG 1
VDR 1
RIG-I 1
CHEK1 1
TOP1mt 1
FLT3 1
PIC1 1
NAC 1
RNA helicase 1
SP1 1
cell cycle checkpoint protein 1
HSP70 1
fra-1 1
C20orf94 1
TBP 1
MYH 1
Chk2 1
DMC1 1
aryl hydrocarbon receptor 1
SE2 1
RECQ1 1
prolactin 1
TP53BP1 1
IKK 1
Polymerase 1
PC3 1
MBD2 1
Mad2 1
REV3L 1
SPTAN1 1
LKB1 1
RMI2 1
nuclear receptor 1
p150 1
heavy chain 1
SPF 1
caspase-9 1
Li-Fraumeni syndrome 1
Fanconi anemia complementation group M 1
RMI1 1
MSH5 1
PPP1R13L 1
PU.1 1
single-stranded DNA binding protein 1
PAR 1
RAR 1
SP2 1
TOP2A 1
Disease
XPF 549
XPG 145
cancer 123
xeroderma pigmentosum 111
XPD 82
XPB 46
anemia 41
Fanconi 41
Cockayne syndrome 33
tumor 32
carcinogenesis 28
skin cancer 23
XP-A 21
BLM 17
breast cancer 16
CSB 15
CSB 15
lung cancer 14
ATM 12
XPE 10
trichothiodystrophy 9
melanoma 9
ovarian cancer 8
non-small cell lung cancer 8
colorectal cancer 8
squamous cell carcinoma 8
WRN 8
progeria 8
genetic disorder 7
carcinoma 6
prostate cancer 5
premature aging 5
metastases 5
lung carcinoma 5
bladder cancer 4
CSA 4
tumor progression 4
Fanconi syndrome 3
DDP 3
Recruitment 3
photosensitivity 3
acute promyelocytic leukemia 2
gastric cancer 2
FANCI 2
FANCJ 2
pancreatic cancer 2
psoriasis 2
testicular cancer 2
neuroblastoma 2
Huntington's disease 2
tumorigenesis 2
adenocarcinoma 2
glioma 2
colon cancer 2
APC 2
acute myeloid leukemia 2
herpes simplex 2
CEP 2
cutaneous melanoma 2
ATRX 2
liver cancer 1
FANCD1 1
residual disease 1
Klebsiella 1
meningioma 1
Alzheimer's disease 1
tumor growth 1
polyneuropathy 1
HIV 1
leukopenia 1
rectal cancer 1
pheochromocytoma 1
WT1 1
brain atrophy 1
brittle hair 1
bone disease 1
leukemia 1
skin disease 1
PCC 1
mental retardation 1
MRT 1
degenerative disc disease 1
cognitive impairment 1
neoplastic transformation 1
osteoporosis 1
osteosarcoma 1
lipodystrophy 1
myelodysplastic syndrome 1
basal cell carcinoma 1
renal cell carcinoma 1
infertility 1
PTD 1
male infertility 1
FAS 1
glioblastoma 1
esophageal cancer 1
SMC 1
endometrial cancer 1
esophageal cancer 1
preeclampsia 1
epithelial ovarian cancer 1
AN2 1
Li-Fraumeni syndrome 1
Prostate Cancer 1
GSH 1
obesity 1
atherosclerosis 1
worms 1
mental retardation 1
Ovary 1
XPV 1
cold 1
UVS 1
Ovary 1
angiosarcoma 1
liver cancer 1
muscular atrophy 1
freckles 1
lymphoma 1
hepatocellular carcinoma 1
Melanoma 1
renal cancer 1
peripheral neuropathy 1
DM1 1
MCF 1
Symptom
collapse 4
cerebellar ataxia 2
starvation 2
ataxia 2
chorea 2
erythema 2
pain 1
photophobia 1
nausea 1
skin damage 1
vomiting 1
Drug
BLM 12
Mutagen 9
Dermatol 6
Asn 4
ROS 2
Trabectedin 2
caffeine 2
DNase I 2
Reserpine 1
Irofulven 1
lactose 1
FLP 1
Rauwolfia serpentina 1
Emodin 1
Tirapazamine 1
Emodin 1
Fragment 1
ascorbate 1
Oxaliplatin 1
lysine 1
ACT 1
GEO 1
G418 1
Enzyme
endonuclease 175
DNA polymerase 10
endonuclease VII 7
DNase 7
luciferase 5
topoisomerase 5
ERK 5
proteasome 5
topoisomerase 5
RNA polymerase 4
PARP 4
hypoxanthine-guanine phosphoribosyltransferase 2
protein kinase 2
mitogen-activated protein kinase 2
ATPase 2
AGT 2
PAT 2
DNA ligase 2
adenine phosphoribosyltransferase 2
CEP 2
Fpg protein 2
APC 2
CEP 2
DNA ligase 2
caspase-9 1
polynucleotide kinase 1
IKK 1
PAH 1
lipoprotein lipase 1
NQO1 1
cytosine deaminase 1
beta-galactosidase 1
lactate dehydrogenase 1
polo-like kinase 1 1
cdc2 1
caspase-3 1
MEK 1
glutathione S-transferase 1
TdT 1
phosphodiesterase 1
microsomal epoxide hydrolase 1
Compound
DNA 475
XPA 113
XPA 113
Dec 39
pyrimidine 18
pyrimidine 18
BLM 13
oxygen 10
leucine 10
ATP 8
DDP 8
nitrogen 7
arginine 6
Asp 6
salt 5
phosphate 5
Clin 5
pyrene 4
tyrosine 4
sodium 4
chromium 4
Gemcitabine 4
MMC 4
His 4
methyl methanesulfonate 4
Gemcitabine 4
Benzo[a]pyrene 3
lysine 3
water 3
hydrogen 3
HN2 3
Emodin 2
chromate 2
formaldehyde 2
formaldehyde 2
phenol 2
PAT 2
NH2 2
PEG 2
acetate 2
ADP 2
2-(dimethylamino)ethyl 2
caffeine 2
silver 2
DCC 2
MIC 2
Arsenic 2
glycerol 2
ADP 2
2-(dimethylamino)ethyl 2
Psoralen 2
ADP 2
Phe 2
Hydrochlorothiazide 1
Catechol 1
H2O2 1
Vinyl chloride 1
SPF 1
Glycidol 1
DAC 1
glutamine 1
dimethylarsinic acid 1
PEI 1
PAH 1
manganese 1
1,2,4-benzotriazine 1
Emodin 1
RU-486 1
1,2-ethanediamine 1
GSH 1
MOP 1
calcium 1
serine 1
NADPH 1
vinyl 1
dimethylarsinic acid 1
TMP 1
PAR 1
tryptophan 1
DPC 1
dimethylarsinic acid 1
MTT 1
Catechol 1
L-PAM 1
NaAsO2 1
ethanol 1
dimethylarsinic acid 1
nicotinamide 1
XTT 1
Gly 1
LPC 1
L-PAM 1
hydroxylamine 1
ATF 1
acetic acid 1
Angelicin 1
Reserpine 1
MEK 1
Histone 1
NADPH 1
galactose 1
dimethylarsinic acid 1
GSH 1
Ribose 1
Panam 1
dimethylarsinic acid 1
1,2-ethanediamine 1
glucose 1
2-nonenal 1
TMP 1
TMP 1
NTA 1
dUDP 1
Ondansetron 1
hydroxylamine 1
TBP 1
methane 1
Hypericin 1
methionine 1
threonine 1
methanol 1
TMP 1
N-acetylcysteine 1
anthracene 1
cysteine 1
sulfate 1
DPC 1
PEI 1
Sitosterol 1
alanine 1
Illudin S 1
5-Hydroxymethyluracil 1
TBP 1
ADP-ribose 1
proline 1