Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C0268140 (
XPF
)
549
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
XPF
519
ERCC1
315
endonuclease
175
XPG
136
XPA
116
XPC
97
XPD
72
Mol
71
ERCC4
44
XPB
39
Sep
39
TFIIH
39
MUS81
35
helicase
32
RPA
31
EME1
23
NER
23
XRCC3
21
ERCC1 protein
18
proliferating cell nuclear antigen
17
XRCC1
16
TRF2
16
FANCD2
16
BRCA1
16
p53
15
CSB
15
CPF
13
BRCA2
12
HR23B
12
BLM
12
ERCC5
11
MSH2
11
telomeric
11
ERCC2
11
histone
10
ATM
10
XPE
10
XRCC2
9
DNA polymerase
9
ATR
9
more...
Disease
XPF
549
XPG
145
cancer
123
xeroderma pigmentosum
111
XPD
82
XPB
46
anemia
41
Fanconi
41
Cockayne syndrome
33
tumor
32
carcinogenesis
28
skin cancer
23
XP-A
21
BLM
17
breast cancer
16
CSB
15
CSB
15
lung cancer
14
ATM
12
XPE
10
trichothiodystrophy
9
melanoma
9
ovarian cancer
8
non-small cell lung cancer
8
colorectal cancer
8
progeria
8
squamous cell carcinoma
8
WRN
8
genetic disorder
7
carcinoma
6
premature aging
5
prostate cancer
5
metastases
5
lung carcinoma
5
tumor progression
4
CSA
4
bladder cancer
4
photosensitivity
3
Fanconi syndrome
3
Recruitment
3
more...
Symptom
collapse
4
cerebellar ataxia
2
starvation
2
ataxia
2
chorea
2
erythema
2
pain
1
photophobia
1
nausea
1
skin damage
1
vomiting
1
Drug
BLM
12
Mutagen
9
Dermatol
6
Asn
4
ROS
2
Trabectedin
2
caffeine
2
DNase I
2
Reserpine
1
Irofulven
1
lactose
1
FLP
1
Rauwolfia serpentina
1
Emodin
1
Tirapazamine
1
Emodin
1
Fragment
1
ascorbate
1
Oxaliplatin
1
lysine
1
ACT
1
GEO
1
G418
1
Enzyme
endonuclease
175
DNA polymerase
10
DNase
7
endonuclease VII
7
topoisomerase
5
topoisomerase
5
ERK
5
proteasome
5
luciferase
5
RNA polymerase
4
PARP
4
hypoxanthine-guanine phosphoribosyltransferase
2
protein kinase
2
CEP
2
ATPase
2
mitogen-activated protein kinase
2
AGT
2
PAT
2
DNA ligase
2
adenine phosphoribosyltransferase
2
CEP
2
Fpg protein
2
APC
2
DNA ligase
2
caspase-9
1
polynucleotide kinase
1
IKK
1
PAH
1
lipoprotein lipase
1
NQO1
1
beta-galactosidase
1
cytosine deaminase
1
cdc2
1
caspase-3
1
MEK
1
polo-like kinase 1
1
glutathione S-transferase
1
TdT
1
phosphodiesterase
1
microsomal epoxide hydrolase
1
more...
Compound
DNA
475
XPA
113
XPA
113
Dec
39
pyrimidine
18
pyrimidine
18
BLM
13
oxygen
10
leucine
10
ATP
8
DDP
8
nitrogen
7
arginine
6
Asp
6
salt
5
phosphate
5
Clin
5
MMC
4
Gemcitabine
4
chromium
4
His
4
pyrene
4
sodium
4
methyl methanesulfonate
4
tyrosine
4
Gemcitabine
4
Benzo[a]pyrene
3
lysine
3
HN2
3
water
3
hydrogen
3
NH2
2
Emodin
2
formaldehyde
2
chromate
2
phenol
2
formaldehyde
2
PEG
2
Phe
2
acetate
2
more...