Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C0268140 (
XPF
)
549
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
XPF
519
ERCC1
315
endonuclease
175
XPG
136
XPA
116
XPC
97
XPD
72
Mol
71
ERCC4
44
TFIIH
39
Sep
39
XPB
39
MUS81
35
helicase
32
RPA
31
NER
23
EME1
23
XRCC3
21
ERCC1 protein
18
proliferating cell nuclear antigen
17
BRCA1
16
TRF2
16
XRCC1
16
FANCD2
16
CSB
15
p53
15
CPF
13
HR23B
12
BRCA2
12
BLM
12
MSH2
11
ERCC2
11
telomeric
11
ERCC5
11
ATM
10
XPE
10
histone
10
XRCC2
9
ATR
9
DNA polymerase
9
RAD51
9
FANCM
9
ubiquitin
8
H2AX
8
ATP
8
DDB2
8
trichothiodystrophy
8
ubiquitin ligase
7
DNA repair endonuclease XPF
7
NMR
7
NBS1
7
excision repair cross-complementing 1
7
topoisomerase I
6
MLH1
6
FANCA
6
OGG1
6
ERCC6
6
hHR23B
6
excision repair protein
6
proteasome
5
MSH3
5
APE1
5
EXO1
5
PARP1
5
ERCC3
5
XPV
5
SOD
5
WRN
5
DNA helicase
4
Chk1
4
Pol
4
SUMO
4
TRF1
4
SNM1A
4
ERCC4 protein
4
CSA
4
cancer susceptibility
4
p21
4
RAD1
4
cytochrome P450
4
RNA polymerase II
4
GSTP1
4
MF1
4
DNA-dependent protein kinase
4
Fanconi anemia protein
4
Gen
4
FANCC
4
tyrosyl-DNA phosphodiesterase 1
4
histone H2A
3
DDP
3
ATRIP
3
Werner syndrome
3
DNA polymerase delta
3
NAT2
3
FEN1
3
HN2
3
RAD
3
GSTT1
3
MRE11
3
DDB1
3
Ku86
3
Rad51
3
UTR
3
Fanconi anemia, complementation group A
3
BTBD12
3
SPO
3
TOP1
3
hOGG1
3
PARP
3
TDP1
3
XRCC5
3
FAAP24
3
CYP1A1
3
core protein
3
FHIT
2
ADP
2
D. melanogaster
2
PMS2
2
APC
2
novel gene
2
DCC
2
cryptic
2
AGT
2
mTOR
2
caspase-3
2
DNA ligase I
2
deoxyribonuclease
2
MEH
2
CEP
2
cyclin D1
2
xenobiotic
2
E3 ubiquitin ligase
2
ATPase
2
POLH
2
UV20
2
TopBP1
2
CYP2E1
2
Ku70
2
RFC
2
HUS1
2
phosphatase
2
p34
2
Bloom syndrome
2
H2A
2
HD1
2
RAD54
2
poly(ADP-ribose) polymerase
2
single-stranded DNA-binding protein
2
PLK1
2
mer
2
TOP3
2
RAD50
2
DNA repair protein
2
insulin
2
CHK2
2
CAK
2
fascin
2
CRL4
2
POLQ
2
AMP
2
ROS
2
general transcription factor
2
FANCJ
2
RPA70
2
transcriptional factor
2
HD2
2
fused
2
methylguanine-DNA methyltransferase
2
c-Jun
2
MIC
2
polypeptide
2
MUS81 endonuclease
2
RAD23B
2
CFP
2
FANCI
2
pol
2
GSTM1
2
ATRX
2
promyelocytic leukemia
2
non-catalytic
2
p97
2
DNase I
2
telomeric repeat binding factor 2
2
hMLH1
2
p70
2
LIG3
2
HPRT
2
POLB
2
DNA repair enzyme
2
FANCF
2
CTCF
2
transcription factor TFIIH
2
AP-1
2
endonuclease III
2
She
1
TAF
1
NQO1
1
Maf
1
hMSH3
1
CYP19
1
CtIP
1
BTR
1
CYP2D6
1
RAD26
1
Proliferating cell nuclear antigen
1
ADH2
1
thymus
1
FOXO3
1
BRCAI
1
MRE11A
1
AlkB
1
SAGE
1
p60
1
AML
1
POLD3
1
SP3
1
TOPBP1
1
HS3
1
Sp1
1
ARTEMIS
1
TESS
1
ATF
1
SMC1A
1
Ku80
1
CD95L
1
FHOD1
1
MI-ER1
1
MLR
1
reductase
1
insulin-like growth factor 1
1
IL6
1
p16
1
SWI
1
ataxin-3
1
UGT1A6
1
RNA helicase family
1
MER3
1
CDK2
1
Wip1
1
p62
1
CASP9
1
calpain
1
SYCP1
1
alpha-spectrin
1
GDX
1
CCK
1
MSH4
1
GATC
1
endoplasmic reticulum
1
TEX11
1
TAF12
1
serine/threonine kinase
1
c-fos
1
A-T
1
ACT
1
glucagon receptor
1
DNA-binding protein
1
CAF-1
1
hemoglobin
1
CPD
1
ras
1
beta-actin
1
CENP-E
1
exonuclease 1
1
C9orf84
1
GTF2H5
1
zinc finger
1
EME2
1
p13
1
RAD18
1
beta-globin
1
RPA2
1
p57
1
DNA-binding domain
1
hypoxanthine-guanine phosphoribosyltransferase
1
Smad3
1
p65
1
PARP-1
1
TERF2IP
1
MLH3
1
histone H2B
1
DNMT1
1
RRM1
1
cytochrome
1
CYP1B1
1
DAC
1
Met
1
TMP
1
growth hormone
1
cIAP1
1
Eg5
1
tumor necrosis factor
1
erythroid
1
MEK
1
zinc finger motif
1
hMSH2
1
MutY homolog
1
histone deacetylase
1
MRI
1
Glutathione S-transferase
1
CDK12
1
MRP
1
Cdc5
1
IAP2
1
CIP1/WAF1
1
oxidoreductase
1
glutathione S-transferase
1
ubiquitin-conjugating enzyme
1
flap endonuclease 1
1
SSA
1
p44
1
telomeric DNA binding protein
1
Barth syndrome
1
UVS
1
GCF
1
MRX
1
RAR-beta
1
PTEN
1
cyclin E
1
MTHFR
1
more...
Disease
XPF
549
XPG
145
cancer
123
xeroderma pigmentosum
111
XPD
82
XPB
46
anemia
41
Fanconi
41
Cockayne syndrome
33
tumor
32
carcinogenesis
28
skin cancer
23
XP-A
21
BLM
17
breast cancer
16
CSB
15
CSB
15
lung cancer
14
ATM
12
XPE
10
trichothiodystrophy
9
melanoma
9
ovarian cancer
8
non-small cell lung cancer
8
colorectal cancer
8
squamous cell carcinoma
8
WRN
8
progeria
8
genetic disorder
7
carcinoma
6
prostate cancer
5
premature aging
5
metastases
5
lung carcinoma
5
bladder cancer
4
CSA
4
tumor progression
4
Fanconi syndrome
3
DDP
3
Recruitment
3
photosensitivity
3
acute promyelocytic leukemia
2
gastric cancer
2
FANCI
2
FANCJ
2
pancreatic cancer
2
psoriasis
2
testicular cancer
2
neuroblastoma
2
Huntington's disease
2
tumorigenesis
2
adenocarcinoma
2
glioma
2
colon cancer
2
APC
2
acute myeloid leukemia
2
herpes simplex
2
CEP
2
cutaneous melanoma
2
ATRX
2
liver cancer
1
FANCD1
1
residual disease
1
Klebsiella
1
meningioma
1
Alzheimer's disease
1
tumor growth
1
polyneuropathy
1
HIV
1
leukopenia
1
rectal cancer
1
pheochromocytoma
1
WT1
1
brain atrophy
1
brittle hair
1
bone disease
1
leukemia
1
skin disease
1
PCC
1
mental retardation
1
MRT
1
degenerative disc disease
1
cognitive impairment
1
neoplastic transformation
1
osteoporosis
1
osteosarcoma
1
lipodystrophy
1
myelodysplastic syndrome
1
basal cell carcinoma
1
renal cell carcinoma
1
infertility
1
PTD
1
male infertility
1
FAS
1
glioblastoma
1
esophageal cancer
1
SMC
1
endometrial cancer
1
esophageal cancer
1
preeclampsia
1
epithelial ovarian cancer
1
AN2
1
Li-Fraumeni syndrome
1
Prostate Cancer
1
GSH
1
obesity
1
atherosclerosis
1
worms
1
mental retardation
1
Ovary
1
XPV
1
cold
1
UVS
1
Ovary
1
angiosarcoma
1
liver cancer
1
muscular atrophy
1
freckles
1
lymphoma
1
hepatocellular carcinoma
1
Melanoma
1
renal cancer
1
peripheral neuropathy
1
DM1
1
MCF
1
Symptom
collapse
4
cerebellar ataxia
2
starvation
2
ataxia
2
chorea
2
erythema
2
pain
1
photophobia
1
nausea
1
skin damage
1
vomiting
1
Drug
BLM
12
Mutagen
9
Dermatol
6
Asn
4
ROS
2
Trabectedin
2
caffeine
2
DNase I
2
Reserpine
1
Irofulven
1
lactose
1
FLP
1
Rauwolfia serpentina
1
Emodin
1
Tirapazamine
1
Emodin
1
Fragment
1
ascorbate
1
Oxaliplatin
1
lysine
1
ACT
1
GEO
1
G418
1
Enzyme
endonuclease
175
DNA polymerase
10
endonuclease VII
7
DNase
7
luciferase
5
topoisomerase
5
ERK
5
proteasome
5
topoisomerase
5
RNA polymerase
4
PARP
4
hypoxanthine-guanine phosphoribosyltransferase
2
protein kinase
2
mitogen-activated protein kinase
2
ATPase
2
AGT
2
PAT
2
DNA ligase
2
adenine phosphoribosyltransferase
2
CEP
2
Fpg protein
2
APC
2
CEP
2
DNA ligase
2
caspase-9
1
polynucleotide kinase
1
IKK
1
PAH
1
lipoprotein lipase
1
NQO1
1
cytosine deaminase
1
beta-galactosidase
1
lactate dehydrogenase
1
polo-like kinase 1
1
cdc2
1
caspase-3
1
MEK
1
glutathione S-transferase
1
TdT
1
phosphodiesterase
1
microsomal epoxide hydrolase
1
Compound
DNA
475
XPA
113
XPA
113
Dec
39
pyrimidine
18
pyrimidine
18
BLM
13
oxygen
10
leucine
10
ATP
8
DDP
8
nitrogen
7
arginine
6
Asp
6
salt
5
phosphate
5
Clin
5
pyrene
4
tyrosine
4
sodium
4
chromium
4
Gemcitabine
4
MMC
4
His
4
methyl methanesulfonate
4
Gemcitabine
4
Benzo[a]pyrene
3
lysine
3
water
3
hydrogen
3
HN2
3
Emodin
2
chromate
2
formaldehyde
2
formaldehyde
2
phenol
2
PAT
2
NH2
2
PEG
2
acetate
2
ADP
2
2-(dimethylamino)ethyl
2
caffeine
2
silver
2
DCC
2
MIC
2
Arsenic
2
glycerol
2
ADP
2
2-(dimethylamino)ethyl
2
Psoralen
2
ADP
2
Phe
2
Hydrochlorothiazide
1
Catechol
1
H2O2
1
Vinyl chloride
1
SPF
1
Glycidol
1
DAC
1
glutamine
1
dimethylarsinic acid
1
PEI
1
PAH
1
manganese
1
1,2,4-benzotriazine
1
Emodin
1
RU-486
1
1,2-ethanediamine
1
GSH
1
MOP
1
calcium
1
serine
1
NADPH
1
vinyl
1
dimethylarsinic acid
1
TMP
1
PAR
1
tryptophan
1
DPC
1
dimethylarsinic acid
1
MTT
1
Catechol
1
L-PAM
1
NaAsO2
1
ethanol
1
dimethylarsinic acid
1
nicotinamide
1
XTT
1
Gly
1
LPC
1
L-PAM
1
hydroxylamine
1
ATF
1
acetic acid
1
Angelicin
1
Reserpine
1
MEK
1
Histone
1
NADPH
1
galactose
1
dimethylarsinic acid
1
GSH
1
Ribose
1
Panam
1
dimethylarsinic acid
1
1,2-ethanediamine
1
glucose
1
2-nonenal
1
TMP
1
TMP
1
NTA
1
dUDP
1
Ondansetron
1
hydroxylamine
1
TBP
1
methane
1
Hypericin
1
methionine
1
threonine
1
methanol
1
TMP
1
N-acetylcysteine
1
anthracene
1
cysteine
1
sulfate
1
DPC
1
PEI
1
Sitosterol
1
alanine
1
Illudin S
1
5-Hydroxymethyluracil
1
TBP
1
ADP-ribose
1
proline
1