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Enzyme
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Pivot Concepts:
Gene/Protein
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Target Concepts:
Gene/Protein
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Query: UMLS:C0267964 (
PAA
)
2,561
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
Crosslinked sulfonated polyacrylamide (Cross-
PAA
-SO
3
H) attached to nano-Fe
3
O
4
as a superior catalyst has been used for the synthesis of 3-alkyl-4-phenyl-1,3-thiazole-2(3
H
)-thione derivatives through a three-component reactions of phenacyl bromide or 4-methoxyphenacyl bromide, carbon disulfide and primary amine under reflux condition in ethanol. A proper, atom-economical, straightforward one-pot multicomponent synthetic route for the synthesis of 1,3-thiazoles in good yields has been devised using crosslinked sulfonated polyacrylamide (Cross-
PAA
-SO
3
H) tethered to nano-Fe
3
O
4
. The catalyst has been characterized by Fourier-transform infrared spectroscopy (FT-IR), scanning electron microscope (SEM), dynamic light scattering (DLS), X-ray powder diffraction (XRD), energy-dispersive X-ray spectroscopy (EDS), thermogravimetric analysis (TGA) and vibrating-sample magnetometer (VSM).
BMC
Chem 2019 Dec
PMID:Crosslinked sulfonated polyacrylamide (Cross-PAA-SO
3
H) tethered to nano-Fe
3
O
4
as a superior catalyst for the synthesis of 1,3-thiazoles. 3163 16
