Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0267964 (PAA)
2,561 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Latent reactivable infection was established with HSV in mouse trigeminal ganglion. A number of antiviral drugs (IUDR, acycloguanosine, Ara-A, PAA and PFA), effective against acute CNS infection with HSV, failed to influence the latent infection once established. Neither lipophilic properties of PFA-derivatives nor the combination of Ara-A and acycloguanosine improved the drug-effects on HSV latency.
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PMID:Persistent reactivable latent herpes simplex virus infection in trigeminal ganglia of mice treated with antiviral drugs. 627 Oct 97