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Target Concepts:
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Query: UMLS:C0267964 (
PAA
)
2,561
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
Two new copolymer-grafted silica stationary phases were prepared and employed in hydrophilic interaction chromatography (HILIC).
2-(Dimethylamino)ethyl methacrylate
(DMAEMA) are copolymerized with itaconic acid (IA) and acrylic acid (AA) respectively, via thiol-ene click reaction on silica surface with deep eutectic solvents (DES) as new solvents. The obtained poly(DMAEMA-co-itaconic acid)-grafted silica (Sil-PDM-PIA) and poly(DMAEMA-co-acrylic acid)-grafted silica (Sil-PDM-
PAA
) were characterized by Fourier transform infrared spectroscopy, elemental analysis and solid-state
13
C NMR spectra. Their hydrophilic interaction performances were evaluated by separating nucleosides, nucleobases, saccharides, and amino acids. Compared with previous reported poly(itaconic acid)-grafted silica (Sil-PIA) and poly(acrylic acid)-grafted silica (Sil-
PAA
) stationary phases, these two new copolymer-grafted silica performed higher selectivity and better separation for polar analytes in HILIC.
...
PMID:Two copolymer-grafted silica stationary phases prepared by surface thiol-ene click reaction in deep eutectic solvents for hydrophilic interaction chromatography. 3142 Jan 78
