Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0264733 (ventricular dilatation)
 2,163 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Surgical repair of tetralogy of Fallot (ToF) in childhood is associated with generally good outcomes, and almost all children can be expected to survive until adulthood. However, significant pulmonary regurgitation leading to progressive right ventricular dilatation is common in teenagers or young adults because of the nature of the surgical intervention. In patients whose repair included placement of a right ventricle to pulmonary artery conduit, it has been possible to place a stented valve within the conduit to treat this. Pulmonary regurgitation after repair of ToF via a transannular patch technique has historically involved repeat surgery as the dimensions of the right ventricular outflow tract have been too large for commercially available valves. This review summarises the novel transcatheter valves available for management of pulmonary regurgitation after surgical repair of ToF in patients in whom the dimensions of the right ventricular outflow tract have previously been considered too large for transcatheter valve implantation.
 ...
PMID:Recent advances in transcatheter management of pulmonary regurgitation after surgical repair of tetralogy of Fallot. 2990 83

Pulmonary regurgitation and right ventricular dilatation are major determinants of long-term follow up of surgically corrected tetralogy of Fallot. Occasionally, there are undiagnosed associated anomalies, which can exaggerate pulmonary regurgitation. The present report describes long-term effect of major aorto pulmonary collateral on right ventricular volume also a result of successful intervention. <Learning objective: Following pulmonary valvotomy in conotruncal anomalies there is development of significant pulmonary regurgitation. On long-term follow up, they are candidates for pulmonary valve replacement. A thorough search and management of associated defects (such as major aorto pulmonary collaterals, peripheral pulmonary stenosis) can reverse right ventricular dilatation and postpone pulmonary valve placement.>.
 ...
PMID:Unmasking the culprit: MAPCA masquerading as RV failure in post surgical correction of TOF. 3027 49

Patients with congenital heart disease that involves reconstruction of the right ventricular outflow tract must frequently undergo interventions derived from the limited useful life of the surgical canals, which leads to the development of right ventricular dysfunction due to changes in the ventricular geometry and predisposition to lethal arrhythmias, with the consequent risk of reinterventions. The percutaneous pulmonary valvular implant is a new therapeutic alternative, less invasive, compared to surgery, for selected patients. A review of the available literature is made and the initial experience of percutaneous pulmonary valve implantation in a Colombian center of high complexity for the treatment of cardiovascular diseases is described, in two patients with aortic homograft dysfunction in a pulmonary position with double valvular lesion, in which the percutaneous pulmonary valve implant was a successful strategy. Patients with congenital heart disease were chosen, with dysfunctional surgical conduits with stenosis or significant pulmonary insufficiency, with dysfunction and right ventricular dilatation. The standard technique for the implantation of the Melody pulmonary valve was used, without complications during the procedure or one year of follow-up. Percutaneous implantation of the pulmonary valve is a great advance in the management of patients with congenital heart diseases, with favorable results in the short and medium term, allowing the restoration of ventricular function with minimal risk, compared to surgical replacement in selected patients.
 ...
PMID:Percutaneous pulmonary valve implant: Two Colombian case reports. 3295 60


<< Previous 1 2