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Query: UMLS:C0262471 (ENT)
5,307 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Juvenile laryngeal papillomatosis is a rare and benign tumoral disease of childhood characterized by numerous relapses despite complete resection. The ENT treatment of choice is to vaporize the papillomas with a CO2 laser. Since the discovery of a viral etiology (Human Papilloma Virus), resection has been followed by medical attempts to control the disease by using various antiviral treatments. Among the latter, alfa interferon has proved effective during the first six months of treatment. In this article, we report on five cases of refractory juvenile laryngeal papillomatosis treated by excision (CO2 laser in four children, surgical resections in one child) and alpha-r IFN 1.5 x 10(5) U/kg daily. With this strategy, three of the five children are currently disease-free for periods ranging from 22 to 68 months. This series includes one remarkable observation of one child who responded only to double doses of alpha-r IFN, after initial failure at conventional doses. This therapeutic scheme reduced the frequency of relapses in a fourth child. In only one child the treatment did fail to modify the natural course of the disease. Side effects were tolerable and included anorexia (one case), palmar erythema (one case), a flu-like syndrome (two cases) and mild transient transaminase rise (three cases) not precluding further treatment. CO2-laser caused one laryngeal oedema and synechia of the anterior commisure of the vocal laryngeal cords in one other case.
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PMID:Combined CO2-laser and alfa recombinant interferon treatment in five children with juvenile laryngeal papillomatosis. 216 13

Fourteen children aged between 6 months and 7 years (mean age = 3.5 years) were treated by CO2 broncholaser in the ENT Department of Trousseau Hospital. Three groups of diagnostic indication were identified: 1. Granulomas treated after mucosal trauma (tracheotomy, foreign body). 2. Granulomas due to pulmonary and/or lymph node tuberculosis. 3. Adhesions and stenosis secondary to neonatal ventilation. The operative and anesthetic technique is described in detail, together with any possible adverse events. The CO2 broncholaser appears to be a technique of choice in this age group, in which the narrowness of the airways makes any endoscopic procedure difficult. The broncholaser allows the early treatment of obstructive tracheobronchial pathology with its risks of severe ventilatory sequelae.
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PMID:Indications of the carbon dioxide laser in tracheobronchial pathology of the infant and young child: 14 cases. 223 88

From 1971 to 1986, 94 patients suffering from T1 glottic carcinoma underwent cordectomy at the University ENT Clinic of Thessaloniki, Greece. There were five female and 89 male patients with a median age of 61.7 years. Two year survival rate was 93.7 per cent; five year survival rate was 93.2 per cent. Seventeen of the patients suffered recurrence, but 11 of them after laryngectomy or radiotherapy are alive with no sign of the disease. Tracheostomy was not performed in the majority of our cases. The relationship between the site of recurrence and survival as well as the role of radiotherapy before and after cordectomy in some of our patients are discussed. We believe that despite the good results of radiotherapy in T1 carcinoma of the vocal cord and the introduction of other treatment modalities such as CO2 laser, cordectomy by laryngofissure is still of value with very good survival results and minimal discomfort for the patient.
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PMID:Our experience in the surgical treatment of T1 carcinoma of the vocal cord. 234 78

The aim of our retrospective study was to evaluate the efficacy of routine pulse oximetry and capnometry for detection of oesophageal tube misplacement. Patients undergoing ENT interventions at our hospital are routinely monitored by ECG, arterial blood pressure by cuff, capnography, and pulse oximetry. Beat-to-beat values of Sao2 and CO2 waveform were recorded by a graphic printer connected to a microcomputer, ASA I patients were routinely preventilated with FIO2 = 0.3, and ASA II-III patients with FIO2 = 1.0. Anaesthesia was performed by junior anaesthesiologists under the close supervision of a resident. During a 16-month period, 1372 patients were anaesthetized. The records of 21 patients with accidental oesophageal tube misplacement were available for retrospective evaluation. Nine patients were preventilated with FIO2 = 0.3 (ASA I), 12 patients with FIO2 = 1.0 (ASA II-III). Rapid detection of oesophageal tube position as early as the first ventilation is possible by capnometry, because of the highly significant difference in end-tidal CO2 (0.2 +/- 0.2 vol%; tracheal intubation: 3.7 +/- 0.9 vol.%; P less than 0.0001). The present advanced pulse oximetry method does not permit differentiation between oesophageal and tracheal tube position within 30 s in patients preventilated with FIO2 = 1.0. Oesophageal misplacement was detectable within 7.5 +/- 0.9 s in patients preventilated with FIO2 = 0.3 due to a 2.1 +/- 0.8% decrease in Sao2 (P less than 0.001). Our results underscore the significance of capnometry for rapid detection of inadvertent oesophageal intubation. High-resolution pulse oximetry is a valuable supplement but not a substitute for capnometry.
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PMID:Early detection of inadvertent oesophageal intubation: pulse oximetry vs. capnography. 249 9

Carbon dioxide lasers were used in the surgical treatment of 46 patients with various ENT pathologies. They were: benign tumors of the stomatolaryngopharynx, and face, head, neck skin; cicatricial and paralytic stenoses of the larynx and trachea, cicatricial processes in the nasal cavity, chronic hypertrophic rhinitis, chronic hyperplastic lateral and granular pharyngitis. Romashka-II and Skalpel-I CO2 lasers were used, their exposure being 0.3 to 10 s and power being 8 to 80 W. Preliminary results suggest that this approach may be very beneficial.
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PMID:[Use of surgical Co2 lasers in pathological states of ENT organs]. 250 93

High frequency jet ventilation (HFJV) is a new ventilation technique which ensures satisfactory gas exchanges with tidal volumes of about 2 ml . kg-1. A gas mixture under high pressure is "chopped up" by an electrically-controlled solenoid valve and delivered to the patient by an injection system. A specific heater-humidifier is required for optimal humidity and warmth of the gas mixture. HFJV creates a positive end-expiratory pressure effect in the alveoles, and the increase of mean intratracheal pressure observed accurately reflects the increase of mean alveolar pressure. Convection by direct alveolar ventilation plays a determinant role in CO2 clearance under HFJV, the other gas transport mechanisms being accessory. In respiratory failure with shock HFJV is better tolerated haemodynamically than conventional ventilation. The main indications of the new technique are ENT surgery, thoracic and tracheal surgery, lithotripsy, broncho-pleural and oesophago-tracheal fistulae and circulatory shock.
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PMID:[High frequency jet ventilation]. 295 20

The CO2 Laser is used in the treatment of several laryngeal diseases and offers considerable advantages over traditional techniques. New applications of this surgical tool are currently under study for other laryngeal and ENT pathologies. It should be pointed out that there are some limitations to the use of the CO2 Laser; an accurate examination of its indications is needed, as well as a precise knowledge of its techniques and possibilities.
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PMID:CO2 laser in laryngeal microsurgery. 367 37

Isolated failure to thrive in an infant caused by chronic hypoventilation due to hypertrophic adenoids and tonsils, has not been previously described. A 9 month-old infant presented with weight loss and mild clinical respiratory signs. Hypoxemia and CO2 retention, however, were documented by transcutaneous gas measurement, and ENT examination revealed enlarged tonsils and adenoids. Adenoidectomy and tonsillectomy at 9 1/2 months of age completely reversed the patient's hypoventilation and growth pattern. While the exact mechanism of failure to thrive secondary to upper airway obstruction in infancy is not clear, we conclude that routine ENT evaluation should be a regular part of the workup of infants under one year who suffer from failure to thrive.
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PMID:Obstructive hypertrophic adenoids and tonsils as a cause of infantile failure to thrive: reversed by tonsillectomy and adenoidectomy. 403 Feb 40

From July 1979 until December 1982 91 patients have been treated with 143 applications of a Coherent CO2-laser at the ENT Department of Kiel University. At the beginning the laser was applied to the majority of microsurgical indications in the larynx and pharynx. But at the end only some selected indications proved true: the treatment of papillomas, the ablation of the tonsil of the base of the tongue, the ablation of the lateral bands and of laryngeal webs. In the treatment of cancer debulking of large obstructive tumours of the larynx by laser vaporization can be used palliatively or prior to laryngectomy, obviating the need for tracheotomy. Own experiences in the treatment of 23 carcinomas of the vocal cord, considering also the literature, proved that the CO2-laser may be an alternative treatment of early glottic cancers of the middle third of the vocal cords. In the other malignant lesions of the vocal cords the laser may be an additive treatment after failure of radiotherapy and if surgical treatment is not possible.
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PMID:[Experiences with the CO2 laser with special reference to the therapy of vocal cord carcinoma]. 619 99

Discussion of the three types of laser used in medicine (YAG, Argon, CO2). More specifically our experience with the CO2 laser in ENT is explained.
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PMID:[The use of the CO2 laser in otorhinolaryngology]. 641 10


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